Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 203284030

GI number: 203284030

Start: 114029

End: 114781

Strand: Reverse

Name: map [H]

Synonym: BDU_108

Alternate gene names: 203284030

Gene position: 114781-114029 (Counterclockwise)

Preceding gene: 203284031

Following gene: 203284029

Centisome position: 12.32

GC content: 30.81

Gene sequence:

>753_bases
TTGAAATTAAGATTAAAATCTAGAGAAGAAATTGAAAAGATTAAGGCATCAGGTAGACTTTTAGCTCAAACTTTTTTGGA
AATCGAGAAAAATATTGCTCCTGGAATTAACACTAAAACACTTGATTTTATAGCTAGTGATTTTATTACTAAAAATGGAG
GTAAGTCTGCTTTTAAAGGATATAATGGATTTAAAGGGACTATTTGTGCTTCTATAAATGAAGAAGTTATACATGGAATT
CCTGGGAGTAGAATGCTTAAAAATGGGGATGTTATTAGTATTGATTGTGGTGTTGTTTTGAATGGATTTTATTCTGATAT
GGCTAAAACTTTTAAAGTGGGAAAGGTAAGCTCTCAAGTTAGTCGCTTATTAGAAATTACAGAAGCTGCTCTTTATAAAG
GAATTGATGAAATGAAGGTTGGTAATCGAATTTTAGATATTTCGAAGGCTATAGAAAATTATATTAAACCATTTAAGTTT
GGAATTGTTAGAGAATATACGGGGCATGGTGTTGGTTTTTCGTTACATGAAGAGCCAAGTATTCCAAATTATTATGATCC
TTTTTTTAAAAATATTGAAATACGGGAAGGTATGGTTTTGGCAATTGAGCCTATGGTAAATTTAGGAAGTCATAAAGTTT
CTCTTAAGAGTGATGGTTGGACAGTCTTTGCATCTGATCTTAGTTTTTCTGCTCATTTTGAACATACTGTTGCTGTTATT
GATGGTTTGCCTTTAATTTTAAGTAAAGTTTGA

Upstream 100 bases:

>100_bases
GGACTAGAGGCCATTTCAATTGCTAATTCTTTTTATGAAACTAATGAGGGTAAACTTTATATGAATATGATAAAGATATT
TAAAGAGAGGAATTGAATAT

Downstream 100 bases:

>100_bases
TAATACTTAAGTAAATATTTAAAAGATTTGGTTTTATATTATGGAGGTGTATAAAATGAATAAAAATTTTATTTCTGTGT
TTTTTGCTAGTTTTTTAGCT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKLRLKSREEIEKIKASGRLLAQTFLEIEKNIAPGINTKTLDFIASDFITKNGGKSAFKGYNGFKGTICASINEEVIHGI
PGSRMLKNGDVISIDCGVVLNGFYSDMAKTFKVGKVSSQVSRLLEITEAALYKGIDEMKVGNRILDISKAIENYIKPFKF
GIVREYTGHGVGFSLHEEPSIPNYYDPFFKNIEIREGMVLAIEPMVNLGSHKVSLKSDGWTVFASDLSFSAHFEHTVAVI
DGLPLILSKV

Sequences:

>Translated_250_residues
MKLRLKSREEIEKIKASGRLLAQTFLEIEKNIAPGINTKTLDFIASDFITKNGGKSAFKGYNGFKGTICASINEEVIHGI
PGSRMLKNGDVISIDCGVVLNGFYSDMAKTFKVGKVSSQVSRLLEITEAALYKGIDEMKVGNRILDISKAIENYIKPFKF
GIVREYTGHGVGFSLHEEPSIPNYYDPFFKNIEIREGMVLAIEPMVNLGSHKVSLKSDGWTVFASDLSFSAHFEHTVAVI
DGLPLILSKV
>Mature_250_residues
MKLRLKSREEIEKIKASGRLLAQTFLEIEKNIAPGINTKTLDFIASDFITKNGGKSAFKGYNGFKGTICASINEEVIHGI
PGSRMLKNGDVISIDCGVVLNGFYSDMAKTFKVGKVSSQVSRLLEITEAALYKGIDEMKVGNRILDISKAIENYIKPFKF
GIVREYTGHGVGFSLHEEPSIPNYYDPFFKNIEIREGMVLAIEPMVNLGSHKVSLKSDGWTVFASDLSFSAHFEHTVAVI
DGLPLILSKV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=252, Percent_Identity=32.9365079365079, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=30.1204819277108, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1786364, Length=250, Percent_Identity=40.8, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI1788728, Length=214, Percent_Identity=24.2990654205607, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=248, Percent_Identity=31.0483870967742, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323273, Length=236, Percent_Identity=32.6271186440678, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI21355531, Length=251, Percent_Identity=34.2629482071713, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24583427, Length=245, Percent_Identity=33.8775510204082, Blast_Score=150, Evalue=6e-37,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27598; Mature: 27598

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRLKSREEIEKIKASGRLLAQTFLEIEKNIAPGINTKTLDFIASDFITKNGGKSAFKG
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCC
YNGFKGTICASINEEVIHGIPGSRMLKNGDVISIDCGVVLNGFYSDMAKTFKVGKVSSQV
CCCCCCEEEECCCHHHHHCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
SRLLEITEAALYKGIDEMKVGNRILDISKAIENYIKPFKFGIVREYTGHGVGFSLHEEPS
HHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCC
IPNYYDPFFKNIEIREGMVLAIEPMVNLGSHKVSLKSDGWTVFASDLSFSAHFEHTVAVI
CCCCCCHHHCCCEECCCEEEEEECCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHH
DGLPLILSKV
CCCHHHHHCC
>Mature Secondary Structure
MKLRLKSREEIEKIKASGRLLAQTFLEIEKNIAPGINTKTLDFIASDFITKNGGKSAFKG
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCC
YNGFKGTICASINEEVIHGIPGSRMLKNGDVISIDCGVVLNGFYSDMAKTFKVGKVSSQV
CCCCCCEEEECCCHHHHHCCCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
SRLLEITEAALYKGIDEMKVGNRILDISKAIENYIKPFKFGIVREYTGHGVGFSLHEEPS
HHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCC
IPNYYDPFFKNIEIREGMVLAIEPMVNLGSHKVSLKSDGWTVFASDLSFSAHFEHTVAVI
CCCCCCHHHCCCEECCCEEEEEECCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHH
DGLPLILSKV
CCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]