Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 203283966

GI number: 203283966

Start: 46926

End: 47678

Strand: Reverse

Name: plsC [H]

Synonym: BDU_42

Alternate gene names: 203283966

Gene position: 47678-46926 (Counterclockwise)

Preceding gene: 203283967

Following gene: 203283965

Centisome position: 5.12

GC content: 25.76

Gene sequence:

>753_bases
ATGAAAATATTAAGGAGTATTATTACTTATATTAGTTTTTTTTTCTTTGTATTGTTTTTTACTGTTTTATTTTTTGTATT
TTTAGTTTTTAAGATATTTAGATTTGAAAATGCTTTTATAAAATTTATTTTTGTATTGATTAGATTTGCTATTAAGACTT
GTTTATGGTTGTCTGGAATTAAGGTTGTTATTACAAAAGATGATGATTGTTGTTTGAACAAAGATGGTGGTGTGGTAATT
ATTGCAAATCATATTGCGTCAATGGATCCTATTTTTTTAATTTATGTTTTTATAAGGCCTTTTGTAATAGTTGCTAAGAG
ATCGCTTTTAAGTATTCCTTTAGTTAATTTTATATTACTTTCTATGGGAGCTATTTTTGTCAATAGAAGCAGTATAAGAT
CTTCTGCTGTTACTCAACAAAAGGCGACTAAAATTATTAAAGAGGGTGGAGCTATTGGAATTTTTCCTGAAGGAACCAGA
AATAGAGGTGGAAAAACAAAAGATTTTAAAAGAGGTTCTGTTAATTTGGCTTTAAGAACAAATTCTCCAATTGTTCCTGT
TACTTTGCTTAATACACATAAAGTTTTTATTAAAAATTTAATATTAAATTCAGGATTATCAGTATATGTGCATATCCATT
CTTTAATAGATGTTTCTAATTTGACAGATGATGAGAAGGAGCAGCTTCATGTTATTGTGAGAGATAAAATAGTTAAAAAA
TTAGAAAAAATGAAAATTCAGTATAATTGTTGA

Upstream 100 bases:

>100_bases
ATTATTCTTCATCCTATTAAGATTTTAAAAGATGAAGTAAGTTTGCTAAAAAGGCAAAAATTAAAACTTGAGAGAATAGA
GAAATTAGGGTAAAAACCAT

Downstream 100 bases:

>100_bases
TAGGAATTTAAATGAAAAAAAATTTTTATGATGAGAGTAAAATTGTTACCTTATCTTCTCTTGAACATATTAGATTACGA
TCTGGAATGTATATTGGAAG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKILRSIITYISFFFFVLFFTVLFFVFLVFKIFRFENAFIKFIFVLIRFAIKTCLWLSGIKVVITKDDDCCLNKDGGVVI
IANHIASMDPIFLIYVFIRPFVIVAKRSLLSIPLVNFILLSMGAIFVNRSSIRSSAVTQQKATKIIKEGGAIGIFPEGTR
NRGGKTKDFKRGSVNLALRTNSPIVPVTLLNTHKVFIKNLILNSGLSVYVHIHSLIDVSNLTDDEKEQLHVIVRDKIVKK
LEKMKIQYNC

Sequences:

>Translated_250_residues
MKILRSIITYISFFFFVLFFTVLFFVFLVFKIFRFENAFIKFIFVLIRFAIKTCLWLSGIKVVITKDDDCCLNKDGGVVI
IANHIASMDPIFLIYVFIRPFVIVAKRSLLSIPLVNFILLSMGAIFVNRSSIRSSAVTQQKATKIIKEGGAIGIFPEGTR
NRGGKTKDFKRGSVNLALRTNSPIVPVTLLNTHKVFIKNLILNSGLSVYVHIHSLIDVSNLTDDEKEQLHVIVRDKIVKK
LEKMKIQYNC
>Mature_250_residues
MKILRSIITYISFFFFVLFFTVLFFVFLVFKIFRFENAFIKFIFVLIRFAIKTCLWLSGIKVVITKDDDCCLNKDGGVVI
IANHIASMDPIFLIYVFIRPFVIVAKRSLLSIPLVNFILLSMGAIFVNRSSIRSSAVTQQKATKIIKEGGAIGIFPEGTR
NRGGKTKDFKRGSVNLALRTNSPIVPVTLLNTHKVFIKNLILNSGLSVYVHIHSLIDVSNLTDDEKEQLHVIVRDKIVKK
LEKMKIQYNC

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=231, Percent_Identity=25.974025974026, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI15100175, Length=231, Percent_Identity=25.974025974026, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI6041665, Length=158, Percent_Identity=33.5443037974684, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789395, Length=189, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=176, Percent_Identity=27.8409090909091, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320151, Length=170, Percent_Identity=31.7647058823529, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364648, Length=121, Percent_Identity=34.7107438016529, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582856, Length=121, Percent_Identity=34.7107438016529, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582854, Length=121, Percent_Identity=34.7107438016529, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641614, Length=173, Percent_Identity=30.0578034682081, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641612, Length=173, Percent_Identity=30.0578034682081, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28455; Mature: 28455

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILRSIITYISFFFFVLFFTVLFFVFLVFKIFRFENAFIKFIFVLIRFAIKTCLWLSGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KVVITKDDDCCLNKDGGVVIIANHIASMDPIFLIYVFIRPFVIVAKRSLLSIPLVNFILL
EEEEECCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMGAIFVNRSSIRSSAVTQQKATKIIKEGGAIGIFPEGTRNRGGKTKDFKRGSVNLALRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEC
NSPIVPVTLLNTHKVFIKNLILNSGLSVYVHIHSLIDVSNLTDDEKEQLHVIVRDKIVKK
CCCEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LEKMKIQYNC
HHHHHHCCCC
>Mature Secondary Structure
MKILRSIITYISFFFFVLFFTVLFFVFLVFKIFRFENAFIKFIFVLIRFAIKTCLWLSGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KVVITKDDDCCLNKDGGVVIIANHIASMDPIFLIYVFIRPFVIVAKRSLLSIPLVNFILL
EEEEECCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMGAIFVNRSSIRSSAVTQQKATKIIKEGGAIGIFPEGTRNRGGKTKDFKRGSVNLALRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEC
NSPIVPVTLLNTHKVFIKNLILNSGLSVYVHIHSLIDVSNLTDDEKEQLHVIVRDKIVKK
CCCEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LEKMKIQYNC
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]