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The map label for this gene is pstK

Identifier: 20095115

GI number: 20095115

Start: 1681086

End: 1681853

Strand: Reverse

Name: pstK

Synonym: MK1679

Alternate gene names: 20095115

Gene position: 1681853-1681086 (Counterclockwise)

Preceding gene: 20095118

Following gene: 20095114

Centisome position: 99.23

GC content: 60.16

Gene sequence:

>768_bases
TTGCGACTGCTGATACTCACCGGCCCGCCCGGGTCAGGTAAAACGTGTTTCGCGCGGGAGCTGGCTCGGGAACTCCGGCA
GGAAGGCTGGCGAGTGGCCCATGTGGAGGCGGACGCTCTCCGCGGATTCCTATGGGATGAGTTCGACCCGAAACTCGAGC
AGGTGGCCCGGGAACTCTTTTTGAAGTCCGTTGAGACGTGTCTGGACGCCGAGCTAGACCTGGTGATAGCGGACGACACT
AATTACTATTCCAGCATGCGGCGTGAGTTGGCTCTCCTGGCCTTGGAGAGGAAAGTTCCGTGGGGGATAGTGTACCTCCG
TACCGGTTTAGATACGTGCCTACGTAGGAACCGCGAGCGAGGTGAACCTATCCCGGAGGAGGTCGTTCGTAGAATTTATG
ATAGGTTTGAACCACCCGAGCCGGATCGGTGGTGGGAGCGTGCGACCTTGGTTCTAGACGATTCTCGGGTTTCCGAGGAA
GTTCTCGAGTTCGTCGAGTCGGGTCTACGCGTCGAGAAGCCCAAAAAGCGACGTCGGCGCACTGACCCCTCCTCCGTGAA
TGAAGTCGACGTACGCACCCGTCAGGTTATGGGGGAGCTGATGCGTCGACTCTCCGAGACAGGCGCGGCTACCCAAGAGC
TAGGGCGCAAGCTCAGTGAACTGCGCCGTGAGATAGTGTCCTCCGTGGAGGATCCGGAAAAGGCCGTCCGGGAGTTCCGG
CGTCGGGCCGAGGAGGTGATCCGGGAATGCCTGCATGGAGACGGGTGA

Upstream 100 bases:

>100_bases
CGACTCCTCCTTTACCGCCGAAGAAGACGTACCGCTGACCCTTCGATAGCCCGAGTTTCTCCGAGATGCCCATCACCAGA
CCCCCTGGGGGTTACAAAGG

Downstream 100 bases:

>100_bases
ATTGGAACTTCCTGGAGCGTCGCGAGTACCAAGTGTCCGTAGCAGCCGAGATTCTCGATTCAATGGACAACACTCTGGTG
GTGATACCCACCGGGCTAGG

Product: nucletide kinase

Products: NA

Alternate protein names: O-phosphoseryl-tRNA(Sec) kinase; PSTK

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MRLLILTGPPGSGKTCFARELARELRQEGWRVAHVEADALRGFLWDEFDPKLEQVARELFLKSVETCLDAELDLVIADDT
NYYSSMRRELALLALERKVPWGIVYLRTGLDTCLRRNRERGEPIPEEVVRRIYDRFEPPEPDRWWERATLVLDDSRVSEE
VLEFVESGLRVEKPKKRRRRTDPSSVNEVDVRTRQVMGELMRRLSETGAATQELGRKLSELRREIVSSVEDPEKAVREFR
RRAEEVIRECLHGDG

Sequences:

>Translated_255_residues
MRLLILTGPPGSGKTCFARELARELRQEGWRVAHVEADALRGFLWDEFDPKLEQVARELFLKSVETCLDAELDLVIADDT
NYYSSMRRELALLALERKVPWGIVYLRTGLDTCLRRNRERGEPIPEEVVRRIYDRFEPPEPDRWWERATLVLDDSRVSEE
VLEFVESGLRVEKPKKRRRRTDPSSVNEVDVRTRQVMGELMRRLSETGAATQELGRKLSELRREIVSSVEDPEKAVREFR
RRAEEVIRECLHGDG
>Mature_255_residues
MRLLILTGPPGSGKTCFARELARELRQEGWRVAHVEADALRGFLWDEFDPKLEQVARELFLKSVETCLDAELDLVIADDT
NYYSSMRRELALLALERKVPWGIVYLRTGLDTCLRRNRERGEPIPEEVVRRIYDRFEPPEPDRWWERATLVLDDSRVSEE
VLEFVESGLRVEKPKKRRRRTDPSSVNEVDVRTRQVMGELMRRLSETGAATQELGRKLSELRREIVSSVEDPEKAVREFR
RRAEEVIRECLHGDG

Specific function: Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis

COG id: COG4088

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-seryl-tRNA(Sec) kinase family

Homologues:

Organism=Caenorhabditis elegans, GI17556074, Length=249, Percent_Identity=27.3092369477912, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920352, Length=168, Percent_Identity=29.7619047619048, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSTK_METKA (Q8TUS5)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614962.1
- ProteinModelPortal:   Q8TUS5
- SMR:   Q8TUS5
- GeneID:   1478274
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1679
- NMPDR:   fig|190192.1.peg.1675
- OMA:   VIVDDTN
- ProtClustDB:   CLSK876615
- BioCyc:   MKAN190192:MK1679-MONOMER
- InterPro:   IPR013641
- InterPro:   IPR020024
- TIGRFAMs:   TIGR03574

Pfam domain/function: PF08433 KTI12

EC number: =2.7.1.164

Molecular weight: Translated: 29790; Mature: 29790

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLILTGPPGSGKTCFARELARELRQEGWRVAHVEADALRGFLWDEFDPKLEQVARELF
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHH
LKSVETCLDAELDLVIADDTNYYSSMRRELALLALERKVPWGIVYLRTGLDTCLRRNRER
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHC
GEPIPEEVVRRIYDRFEPPEPDRWWERATLVLDDSRVSEEVLEFVESGLRVEKPKKRRRR
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHCCCCCCCCHHHHCC
TDPSSVNEVDVRTRQVMGELMRRLSETGAATQELGRKLSELRREIVSSVEDPEKAVREFR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RRAEEVIRECLHGDG
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLLILTGPPGSGKTCFARELARELRQEGWRVAHVEADALRGFLWDEFDPKLEQVARELF
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHH
LKSVETCLDAELDLVIADDTNYYSSMRRELALLALERKVPWGIVYLRTGLDTCLRRNRER
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHC
GEPIPEEVVRRIYDRFEPPEPDRWWERATLVLDDSRVSEEVLEFVESGLRVEKPKKRRRR
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHCCCCCCCCHHHHCC
TDPSSVNEVDVRTRQVMGELMRRLSETGAATQELGRKLSELRREIVSSVEDPEKAVREFR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RRAEEVIRECLHGDG
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014