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The map label for this gene is rsmB [H]

Identifier: 20095066

GI number: 20095066

Start: 1631366

End: 1632712

Strand: Reverse

Name: rsmB [H]

Synonym: MK1630

Alternate gene names: 20095066

Gene position: 1632712-1631366 (Counterclockwise)

Preceding gene: 20095070

Following gene: 20095063

Centisome position: 96.33

GC content: 65.11

Gene sequence:

>1347_bases
ATGGAGAACCAGCTGCTGGCGGTTAAAGCCTTGGTCCTCGTGGAAACCCGAGGAATGCCGATACCCGAGGCCGTGGAGCG
TACCTGCCGGGACCGTCCGATCGACGTCCGACGGTCCGTGCAGGCGTTCGTGTACGAGACGATCAAGCGGCGGAACCTAC
TGGACGAGCTCGTGGCGGCGGGCTCGGACGCACATCCCGAGGACGTGAGGTCGCCCTACGTGCGCCAGATCCTCAGGGTC
GGCACCCTGGAGATGAAGATCTGGAGAAACCCTCCACCCGCGGTGACCGACTGCATGGTCAGGATCGCGAAGAGGTTAGT
AGGGAGCAAGGCGGGAGCCTTCGTCAACGCCGTGCTCCGCGGCGTGGAACGCGTCTCCGTGAAGGACGTGCTGGAGGATC
GCCCGTGGACGGAGCGCCTCGCACTGAAGTACGGGCATCCCGAGTGGTTCGTCCTTTACGTGCTGGATTTGTTCGAGGGT
GATCGGAGTAGGGTCGAGCTCCTCCTACGCGCGAACAACCGGGTGCCGCCGCAGTACCTCCGTATAAACCGGTTGAAGTT
AGACCCGCTGGTCGCGGGTGACGTCCTGGAGAGAGAGTACGGTATCGTGACGGAGCCCACGTTCCTGGAGGAGGTGCGTG
CGCTGGTCAGGGGCCGCGGATACGGATCGAGGGCTTGGCGGGAGGGACTGTTCGACGTGCAAGACCTCGCGTCGGCGTCC
GCGTCCGCCGCCCTGAGCGCCGAGCCGGGTGAAACCGTGCTCGACGTCTGCGCGGCTCCGGGTAGCAAGACCACGCACAC
GGCGGAGCGCATGCTCGACGAGGGCGAAGTGTGGGCCGTGGACAGGTCGGAGTGGGGACTCCGGGTCCTGGAGCGCCGGT
GCCGCCGGCTCGGGATCACCTGCGTCCGAACTATCTGCCGGGACGCCCGCGGGTTGACGGTGGACGACCTACCCGACGTT
CCAGATCGTATCCTCGTGGACCCACCGTGCTCGACCACGGGGGTCTGGAACAGGAACCCGGACAGTAGGTGGAAGCCCAA
GCCGTTGGAGCGGTTCGCAGAGAGGCAGTGGGAGATACTGGAGCCCGCGCTCCGTATCGCCGAGGAACACGGCTGCACGC
TGGTGTACTCGACGTGCTCGGTATCGTGGGAGGAGAACGAGGCTATCGTGAAGCGCGCCTTGGAGGAGTTCGACGTGAAA
CTGGTCGACGCCGGCGTACTAGGGTCCCCCGGGATCGAGGAGTTCCGAGGGGAGCGGTTCTCTGGGTACAAGAAGGTGCG
GCGGTACTGGCCGTTCAGGCACGACACGGCAGGATTCTTCGTCGCGAAGATGAAGGGAAAAGGGTAG

Upstream 100 bases:

>100_bases
ATGGAATCGTCGATGACCCGGGCTAGGTCTTCAACACGGTCCAGTACCTCTCCGCCCACCTTGATGACCTCCACCGTATC
ACCCGCCGGGGTGGCGATGC

Downstream 100 bases:

>100_bases
GAAAGAAAAAATAGGAAAGAAAAATCAGTCGTAGACGAAGAGTGTCGGGGTCCCCTCTCCCGAGGACCTGTCGAAGAGCC
ATCCGAGGTCCACGGAACCC

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MENQLLAVKALVLVETRGMPIPEAVERTCRDRPIDVRRSVQAFVYETIKRRNLLDELVAAGSDAHPEDVRSPYVRQILRV
GTLEMKIWRNPPPAVTDCMVRIAKRLVGSKAGAFVNAVLRGVERVSVKDVLEDRPWTERLALKYGHPEWFVLYVLDLFEG
DRSRVELLLRANNRVPPQYLRINRLKLDPLVAGDVLEREYGIVTEPTFLEEVRALVRGRGYGSRAWREGLFDVQDLASAS
ASAALSAEPGETVLDVCAAPGSKTTHTAERMLDEGEVWAVDRSEWGLRVLERRCRRLGITCVRTICRDARGLTVDDLPDV
PDRILVDPPCSTTGVWNRNPDSRWKPKPLERFAERQWEILEPALRIAEEHGCTLVYSTCSVSWEENEAIVKRALEEFDVK
LVDAGVLGSPGIEEFRGERFSGYKKVRRYWPFRHDTAGFFVAKMKGKG

Sequences:

>Translated_448_residues
MENQLLAVKALVLVETRGMPIPEAVERTCRDRPIDVRRSVQAFVYETIKRRNLLDELVAAGSDAHPEDVRSPYVRQILRV
GTLEMKIWRNPPPAVTDCMVRIAKRLVGSKAGAFVNAVLRGVERVSVKDVLEDRPWTERLALKYGHPEWFVLYVLDLFEG
DRSRVELLLRANNRVPPQYLRINRLKLDPLVAGDVLEREYGIVTEPTFLEEVRALVRGRGYGSRAWREGLFDVQDLASAS
ASAALSAEPGETVLDVCAAPGSKTTHTAERMLDEGEVWAVDRSEWGLRVLERRCRRLGITCVRTICRDARGLTVDDLPDV
PDRILVDPPCSTTGVWNRNPDSRWKPKPLERFAERQWEILEPALRIAEEHGCTLVYSTCSVSWEENEAIVKRALEEFDVK
LVDAGVLGSPGIEEFRGERFSGYKKVRRYWPFRHDTAGFFVAKMKGKG
>Mature_448_residues
MENQLLAVKALVLVETRGMPIPEAVERTCRDRPIDVRRSVQAFVYETIKRRNLLDELVAAGSDAHPEDVRSPYVRQILRV
GTLEMKIWRNPPPAVTDCMVRIAKRLVGSKAGAFVNAVLRGVERVSVKDVLEDRPWTERLALKYGHPEWFVLYVLDLFEG
DRSRVELLLRANNRVPPQYLRINRLKLDPLVAGDVLEREYGIVTEPTFLEEVRALVRGRGYGSRAWREGLFDVQDLASAS
ASAALSAEPGETVLDVCAAPGSKTTHTAERMLDEGEVWAVDRSEWGLRVLERRCRRLGITCVRTICRDARGLTVDDLPDV
PDRILVDPPCSTTGVWNRNPDSRWKPKPLERFAERQWEILEPALRIAEEHGCTLVYSTCSVSWEENEAIVKRALEEFDVK
LVDAGVLGSPGIEEFRGERFSGYKKVRRYWPFRHDTAGFFVAKMKGKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=334, Percent_Identity=30.8383233532934, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI76150623, Length=334, Percent_Identity=30.8383233532934, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI32698918, Length=176, Percent_Identity=36.9318181818182, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI8922322, Length=292, Percent_Identity=28.7671232876712, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI270288818, Length=292, Percent_Identity=28.7671232876712, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI270288816, Length=292, Percent_Identity=28.7671232876712, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI23199998, Length=223, Percent_Identity=32.2869955156951, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI39995082, Length=271, Percent_Identity=28.7822878228782, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI301336155, Length=271, Percent_Identity=28.7822878228782, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI2367212, Length=419, Percent_Identity=29.5942720763723, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87081985, Length=223, Percent_Identity=36.7713004484305, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=322, Percent_Identity=32.6086956521739, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71998419, Length=217, Percent_Identity=32.7188940092166, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=217, Percent_Identity=32.7188940092166, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324268, Length=234, Percent_Identity=35.042735042735, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319447, Length=263, Percent_Identity=28.8973384030418, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI22024126, Length=224, Percent_Identity=33.4821428571429, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24668781, Length=240, Percent_Identity=34.1666666666667, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356513, Length=240, Percent_Identity=34.1666666666667, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356579, Length=167, Percent_Identity=36.5269461077844, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355201, Length=268, Percent_Identity=29.4776119402985, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50860; Mature: 50860

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQLLAVKALVLVETRGMPIPEAVERTCRDRPIDVRRSVQAFVYETIKRRNLLDELVAA
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GSDAHPEDVRSPYVRQILRVGTLEMKIWRNPPPAVTDCMVRIAKRLVGSKAGAFVNAVLR
CCCCCHHHHCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVERVSVKDVLEDRPWTERLALKYGHPEWFVLYVLDLFEGDRSRVELLLRANNRVPPQYL
HHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEHHHHHHHCCCHHHHHHHHCCCCCCCHHHH
RINRLKLDPLVAGDVLEREYGIVTEPTFLEEVRALVRGRGYGSRAWREGLFDVQDLASAS
EEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHH
ASAALSAEPGETVLDVCAAPGSKTTHTAERMLDEGEVWAVDRSEWGLRVLERRCRRLGIT
HCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
CVRTICRDARGLTVDDLPDVPDRILVDPPCSTTGVWNRNPDSRWKPKPLERFAERQWEIL
HHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EPALRIAEEHGCTLVYSTCSVSWEENEAIVKRALEEFDVKLVDAGVLGSPGIEEFRGERF
HHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCHHHHCCCHH
SGYKKVRRYWPFRHDTAGFFVAKMKGKG
HHHHHHHHHCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MENQLLAVKALVLVETRGMPIPEAVERTCRDRPIDVRRSVQAFVYETIKRRNLLDELVAA
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GSDAHPEDVRSPYVRQILRVGTLEMKIWRNPPPAVTDCMVRIAKRLVGSKAGAFVNAVLR
CCCCCHHHHCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVERVSVKDVLEDRPWTERLALKYGHPEWFVLYVLDLFEGDRSRVELLLRANNRVPPQYL
HHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEHHHHHHHCCCHHHHHHHHCCCCCCCHHHH
RINRLKLDPLVAGDVLEREYGIVTEPTFLEEVRALVRGRGYGSRAWREGLFDVQDLASAS
EEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHH
ASAALSAEPGETVLDVCAAPGSKTTHTAERMLDEGEVWAVDRSEWGLRVLERRCRRLGIT
HCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
CVRTICRDARGLTVDDLPDVPDRILVDPPCSTTGVWNRNPDSRWKPKPLERFAERQWEIL
HHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EPALRIAEEHGCTLVYSTCSVSWEENEAIVKRALEEFDVKLVDAGVLGSPGIEEFRGERF
HHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCHHHHCCCHH
SGYKKVRRYWPFRHDTAGFFVAKMKGKG
HHHHHHHHHCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]