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The map label for this gene is RPR2

Identifier: 20095058

GI number: 20095058

Start: 1624826

End: 1625212

Strand: Reverse

Name: RPR2

Synonym: MK1622

Alternate gene names: 20095058

Gene position: 1625212-1624826 (Counterclockwise)

Preceding gene: 20095061

Following gene: 20095057

Centisome position: 95.88

GC content: 59.43

Gene sequence:

>387_bases
GTGTGCAAGGTCGAATCCCCTCGTTCGGGGGTGTTACTGTTGCGCAGGATAGCCCTGGAGCGCGCTGAGCGGCTGTTGAG
GCTGGCCCGGACGGTGTACTACGAGGACCCGGACAGGGCACGGAGGTACGTGGAGCTCGCCAGGAGGATAGCTATGAAAG
CTCGGGTTAAGCTTCCGAAGCATCTCAAGCGTAGCTTCTGTAAGCGCTGTAACACCCCACTCATCCCCGGGGTCACGGCC
CGAGTACGCTTGAGACAGAACCGCATGCCCCACGTGTCGGTCACCTGCCTCGAGTGTGGCTATATATATCGGTATCCGTA
CTTACGGGAGGTAAAGGAGCGGAGACGCAGGCATATGGAGGGGGTGAAGGATCGTGACGCAGGTTAA

Upstream 100 bases:

>100_bases
GGGCGTCACCGGGACGGTATCCGGATGGACTTCCAGGTAGTGACTCGTCGGATCAGCCTGCGCGGGTGTCATCGGTAGCA
GGAGCCATAGCAGGAGCCAG

Downstream 100 bases:

>100_bases
ACGCCTGAGCGGTAAGGAGCGTAGGGCACTCCGAGCCCGCGCGGTCCTGCTGGATCCCGTTGTGAGGATAGGGAAGAAAG
GACTGACTTCCGGAGTCATC

Product: ribonuclease P protein component 4

Products: NA

Alternate protein names: RNase P component 4

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MCKVESPRSGVLLLRRIALERAERLLRLARTVYYEDPDRARRYVELARRIAMKARVKLPKHLKRSFCKRCNTPLIPGVTA
RVRLRQNRMPHVSVTCLECGYIYRYPYLREVKERRRRHMEGVKDRDAG

Sequences:

>Translated_128_residues
MCKVESPRSGVLLLRRIALERAERLLRLARTVYYEDPDRARRYVELARRIAMKARVKLPKHLKRSFCKRCNTPLIPGVTA
RVRLRQNRMPHVSVTCLECGYIYRYPYLREVKERRRRHMEGVKDRDAG
>Mature_128_residues
MCKVESPRSGVLLLRRIALERAERLLRLARTVYYEDPDRARRYVELARRIAMKARVKLPKHLKRSFCKRCNTPLIPGVTA
RVRLRQNRMPHVSVTCLECGYIYRYPYLREVKERRRRHMEGVKDRDAG

Specific function: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends

COG id: COG2023

COG function: function code J; RNase P subunit RPR2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic/archaeal RNase P protein component 4 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNP4_METKA (Q8TGY1)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614905.1
- ProteinModelPortal:   Q8TGY1
- SMR:   Q8TGY1
- GeneID:   1478217
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1622
- NMPDR:   fig|190192.1.peg.1618
- HOGENOM:   HBG731499
- OMA:   HVVITCL
- ProtClustDB:   PRK03954
- BioCyc:   MKAN190192:MK1622-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00757
- InterPro:   IPR016432
- InterPro:   IPR007175
- PANTHER:   PTHR14742
- PIRSF:   PIRSF004878

Pfam domain/function: PF04032 Rpr2

EC number: =3.1.26.5

Molecular weight: Translated: 15309; Mature: 15309

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKVESPRSGVLLLRRIALERAERLLRLARTVYYEDPDRARRYVELARRIAMKARVKLPK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
HLKRSFCKRCNTPLIPGVTARVRLRQNRMPHVSVTCLECGYIYRYPYLREVKERRRRHME
HHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEHHHHHCCHHHHCHHHHHHHHHHHHHHC
GVKDRDAG
CCCCCCCC
>Mature Secondary Structure
MCKVESPRSGVLLLRRIALERAERLLRLARTVYYEDPDRARRYVELARRIAMKARVKLPK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
HLKRSFCKRCNTPLIPGVTARVRLRQNRMPHVSVTCLECGYIYRYPYLREVKERRRRHME
HHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEHHHHHCCHHHHCHHHHHHHHHHHHHHC
GVKDRDAG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014