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The map label for this gene is GIM5

Identifier: 20095050

GI number: 20095050

Start: 1621798

End: 1622271

Strand: Reverse

Name: GIM5

Synonym: MK1614

Alternate gene names: 20095050

Gene position: 1622271-1621798 (Counterclockwise)

Preceding gene: 20095051

Following gene: 20095049

Centisome position: 95.71

GC content: 58.23

Gene sequence:

>474_bases
ATGGCGGAGAAGAAGAACGAGCAAGAGATCCAACAGGAACTACAGCGACTGATAGCCGAGATCAACAGACTTCAAGGGCA
AATGGAGGCGATCAACGCGCAAATAGACCTCATAGAGTCCTCGATCAGTGAGCTGAACCGAGTCGAGGAGACCTTGAAGG
GCGTTAAAGAGCTGGAGGGCGACGAGGAAGTCCTCGTACCCGTGGGTGCTCAGTCGTTCGTCAGAGCTTGTGTCACCGAC
ACGGAGCGCGTGATCGTGGGTATCGGAGCCGGCGTGGCTGTGGAGAGAACGATCGATGAAGCACTCGAGAGCATCGACGA
CCAGCGGCAGGAGCTAGAGAAAGCCCGCGCGGAAGCACAGCAGAAGCTCCAGGAGCTGGCTCAGGAGTTGCAGGAGAAGC
AGAGGAAGGCACAAGAACTTGCGCAGCAGCTCGAAGGTGCCCAGCGGATCGCCCAGCAGTCCGGTGGAGGGTAA

Upstream 100 bases:

>100_bases
GCGTCAGCCGCATGGAGATTCAGATCGAAGAGATCCGGGAGATAGACCCCTCTAAGGTAGAGGATCCGATACTGAGGCGG
CTTCTGGGTGTGGAAGAGTA

Downstream 100 bases:

>100_bases
TCCTTCCCGAAACCCGACGTTTTTCGGGGGTGCCTTCGAGCTTGTTCGGCAAGATGAAGAGCGTTCTAAGCAAGGTAAAG
GAGAAGGTGGCGAAGCGCGT

Product: prefoldin subunit alpha

Products: NA

Alternate protein names: GimC subunit alpha

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MAEKKNEQEIQQELQRLIAEINRLQGQMEAINAQIDLIESSISELNRVEETLKGVKELEGDEEVLVPVGAQSFVRACVTD
TERVIVGIGAGVAVERTIDEALESIDDQRQELEKARAEAQQKLQELAQELQEKQRKAQELAQQLEGAQRIAQQSGGG

Sequences:

>Translated_157_residues
MAEKKNEQEIQQELQRLIAEINRLQGQMEAINAQIDLIESSISELNRVEETLKGVKELEGDEEVLVPVGAQSFVRACVTD
TERVIVGIGAGVAVERTIDEALESIDDQRQELEKARAEAQQKLQELAQELQEKQRKAQELAQQLEGAQRIAQQSGGG
>Mature_156_residues
AEKKNEQEIQQELQRLIAEINRLQGQMEAINAQIDLIESSISELNRVEETLKGVKELEGDEEVLVPVGAQSFVRACVTDT
ERVIVGIGAGVAVERTIDEALESIDDQRQELEKARAEAQQKLQELAQELQEKQRKAQELAQQLEGAQRIAQQSGGG

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding

COG id: COG1730

COG function: function code O; Predicted prefoldin, molecular chaperone implicated in de novo protein folding

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin subunit alpha family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PFDA_METKA (Q8TUY7)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614897.1
- ProteinModelPortal:   Q8TUY7
- SMR:   Q8TUY7
- GeneID:   1478209
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1614
- NMPDR:   fig|190192.1.peg.1610
- OMA:   YEYQLLQ
- ProtClustDB:   PRK03947
- BioCyc:   MKAN190192:MK1614-MONOMER
- HAMAP:   MF_00308
- InterPro:   IPR011599
- InterPro:   IPR009053
- InterPro:   IPR004127
- TIGRFAMs:   TIGR00293

Pfam domain/function: PF02996 Prefoldin; SSF46579 Prefoldin

EC number: NA

Molecular weight: Translated: 17447; Mature: 17316

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKNEQEIQQELQRLIAEINRLQGQMEAINAQIDLIESSISELNRVEETLKGVKELEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEEVLVPVGAQSFVRACVTDTERVIVGIGAGVAVERTIDEALESIDDQRQELEKARAEAQ
CCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKLQELAQELQEKQRKAQELAQQLEGAQRIAQQSGGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEKKNEQEIQQELQRLIAEINRLQGQMEAINAQIDLIESSISELNRVEETLKGVKELEG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEEVLVPVGAQSFVRACVTDTERVIVGIGAGVAVERTIDEALESIDDQRQELEKARAEAQ
CCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKLQELAQELQEKQRKAQELAQQLEGAQRIAQQSGGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014