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The map label for this gene is Kch_3 [C]

Identifier: 20094985

GI number: 20094985

Start: 1565366

End: 1566451

Strand: Direct

Name: Kch_3 [C]

Synonym: MK1549

Alternate gene names: 20094985

Gene position: 1565366-1566451 (Clockwise)

Preceding gene: 20094984

Following gene: 20094989

Centisome position: 92.35

GC content: 59.67

Gene sequence:

>1144_bases
TTGAAGGCGAAGGTTCGAACGTTCAGATACCTTTGGCACTTACTACGCGACGTGATCAGCGTACCGACCGTGAAGTACGC
GGTCGCATACGTAGCGGCGCTCCTATGCCTGGGTACCCTCGGATACTGGACACTCGAAGGACGGTCGCCTGTCGACGCGT
TCTACACCACGGTCCTGATCCTAACCGGGGTCGGATGCGCCAATCCACCCACGACACCCGCGGGTGAGATCTTCACGGTA
GGCCTCCTAGCCGTGGGTCTCGGGGCGCTCATTCACATCATTTCGAGGGTATTTGCCGCACTTCTGCGGGGAGACGTTCT
GTTGCGCATCAAAGAGAGTGACGCGATGGCACGGATAGAGCGCATGCGCGATCACGTAGTGATATGTGGGTACGGCAAGA
AGGGTCGTGAGATAGCCCGCAACTTAGGGGAGCACGGGTTCGAGGTCGTGGTTGTGGACAAAGACCCGGAAAAGTGCGAT
CGGGCCTTCCGTGACGGCCACTTGGCGGTGCAAGGCGACGTGACCTCGGAAGAGACGCTACTGAAGGCCGGGGTGGAACG
CGCGCAGGCCGTGGCACTGGTCACCGATTCCGACGAAACTAACGTCTTCGCCTGTGTGCTGGTTCGCGACCTTAACCCGG
ACGCGTGGATAGTGGCGGCGGCTCGGTCCAAGACCGGTGCAAGGACCCTGCTACGTGCCGGGGCCGACGAGGTGGTGAGG
GTGTACGAGGCGGCGGGGATAGTCATAGCCAATAGGTTGATGGACCCTCTGTCGTTCCTGGTGACGGTGAGGCATCCGCT
GGAAGACACCTTCCGAGAGTTCCGTGAGATCATAAGACACGGCGGAATAGTCGTCGACGTCCGGTACCACATCCCCTCGT
TACCGGAGCCGTTGGTGAAGGACCTCTGGGTGGAGGATGAGAGCGACGTGAAACGGCGCCTGGAAATGCACGAAGACTCG
GAGACTAGAGAGGCCCTGGAGAGGCTTCATAGGATGTCGGACGACGTTCATTCTCACCGTATCATAGTTCGGCGGGAAGA
GGACAAGGAAAAGATCGTGGAGGCACTTCGGAGGCTCGTTCCTGATCGGAGTCGACATGACTCACAAAGAGGTTTTGAAG
GAGGTGTTCGGAGTGGAGGCGTGA

Upstream 100 bases:

>100_bases
AGGACGCGGCGGAAGGCAAGCTGAAAGCCCGTCCCCCCGCCGTTGTCGTGGTGGGAGAGGTCGTCAAGTGGTGGAGGGAG
GTACTGGGTAGGGAGACGCG

Downstream 100 bases:

>100_bases
GTTTCACGCCTCGATTACCCGGAGCGCCGTCTTCGCTACGGCTTCCACGGTGTGTTCTTCGGCCTCCACGACCTTCAAGC
CGGCTCTTCGGAGCTCCTTG

Product: fused NAD-binding/uncharacterized domain-containing protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: MjK1 [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>380_residues
MKAKVRTFRYLWHLLRDVISVPTVKYAVAYVAALLCLGTLGYWTLEGRSPVDAFYTTVLILTGVGCANPPTTPAGEIFTV
GLLAVGLGALIHIISRVFAALLRGDVLLRIKESDAMARIERMRDHVVICGYGKKGREIARNLGEHGFEVVVVDKDPEKCD
RAFRDGHLAVQGDVTSEETLLKAGVERAQAVALVTDSDETNVFACVLVRDLNPDAWIVAAARSKTGARTLLRAGADEVVR
VYEAAGIVIANRLMDPLSFLVTVRHPLEDTFREFREIIRHGGIVVDVRYHIPSLPEPLVKDLWVEDESDVKRRLEMHEDS
ETREALERLHRMSDDVHSHRIIVRREEDKEKIVEALRRLVPDGVDMTHKEVLKEVFGVEA

Sequences:

>Translated_362_residues
MKAKVRTFRYLWHLLRDVISVPTVKYAVAYVAALLCLGTLGYWTLEGRSPVDAFYTTVLILTGVGCANPPTTPAGEIFTV
GLLAVGLGALIHIISRVFAALLRGDVLLRIKESDAMARIERMRDHVVICGYGKKGREIARNLGEHGFEVVVVDKDPEKCD
RAFRDGHLAVQGDVTSEETLLKAGVERAQAVALVTDSDETNVFACVLVRDLNPDAWIVAAARSKTGARTLLRAGADEVVR
VYEAAGIVIANRLMDPLSFLVTVRHPLEDTFREFREIIRHGGIVVDVRYHIPSLPEPLVKDLWVEDESDVKRRLEMHEDS
ETREALERLHRMSDDVHSHRIIVRREEDKEKIVEALRRLVPD
>Mature_362_residues
MKAKVRTFRYLWHLLRDVISVPTVKYAVAYVAALLCLGTLGYWTLEGRSPVDAFYTTVLILTGVGCANPPTTPAGEIFTV
GLLAVGLGALIHIISRVFAALLRGDVLLRIKESDAMARIERMRDHVVICGYGKKGREIARNLGEHGFEVVVVDKDPEKCD
RAFRDGHLAVQGDVTSEETLLKAGVERAQAVALVTDSDETNVFACVLVRDLNPDAWIVAAARSKTGARTLLRAGADEVVR
VYEAAGIVIANRLMDPLSFLVTVRHPLEDTFREFREIIRHGGIVVDVRYHIPSLPEPLVKDLWVEDESDVKRRLEMHEDS
ETREALERLHRMSDDVHSHRIIVRREEDKEKIVEALRRLVPD

Specific function: Potassium channel protein. Seems to conduct potassium at low membrane potentials [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=207, Percent_Identity=25.1207729468599, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003280
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 40552; Mature: 40552

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKVRTFRYLWHLLRDVISVPTVKYAVAYVAALLCLGTLGYWTLEGRSPVDAFYTTVLI
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHH
LTGVGCANPPTTPAGEIFTVGLLAVGLGALIHIISRVFAALLRGDVLLRIKESDAMARIE
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
RMRDHVVICGYGKKGREIARNLGEHGFEVVVVDKDPEKCDRAFRDGHLAVQGDVTSEETL
HHHCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEECCCCCHHHH
LKAGVERAQAVALVTDSDETNVFACVLVRDLNPDAWIVAAARSKTGARTLLRAGADEVVR
HHHHHHHHHEEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHCCHHHHHH
VYEAAGIVIANRLMDPLSFLVTVRHPLEDTFREFREIIRHGGIVVDVRYHIPSLPEPLVK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHH
DLWVEDESDVKRRLEMHEDSETREALERLHRMSDDVHSHRIIVRREEDKEKIVEALRRLV
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHCEEEEEECCCHHHHHHHHHHHC
PD
CC
>Mature Secondary Structure
MKAKVRTFRYLWHLLRDVISVPTVKYAVAYVAALLCLGTLGYWTLEGRSPVDAFYTTVLI
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHH
LTGVGCANPPTTPAGEIFTVGLLAVGLGALIHIISRVFAALLRGDVLLRIKESDAMARIE
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
RMRDHVVICGYGKKGREIARNLGEHGFEVVVVDKDPEKCDRAFRDGHLAVQGDVTSEETL
HHHCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEECCCCCHHHH
LKAGVERAQAVALVTDSDETNVFACVLVRDLNPDAWIVAAARSKTGARTLLRAGADEVVR
HHHHHHHHHEEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHCCHHHHHH
VYEAAGIVIANRLMDPLSFLVTVRHPLEDTFREFREIIRHGGIVVDVRYHIPSLPEPLVK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHH
DLWVEDESDVKRRLEMHEDSETREALERLHRMSDDVHSHRIIVRREEDKEKIVEALRRLV
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHCEEEEEECCCHHHHHHHHHHHC
PD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]