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The map label for this gene is Dcm [C]

Identifier: 20094956

GI number: 20094956

Start: 1532641

End: 1533588

Strand: Reverse

Name: Dcm [C]

Synonym: MK1520

Alternate gene names: 20094956

Gene position: 1533588-1532641 (Counterclockwise)

Preceding gene: 20094969

Following gene: 20094953

Centisome position: 90.48

GC content: 60.86

Gene sequence:

>948_bases
TTGAAGCCGAAAGTTGTGGATCTCTTCTGCGGAGCCGGCGGTTTCTCCAGGGGTTTCAAGGAAGCTGGGTTCAAGATCCT
CGGGGGTGTTGAAAACAACCCCGCGCCGGCCGCGACCTACCGGGAGAATTTCCCAGAGGCCGAGGTGATCGAACGCGACA
TCCAGCGGGTCGACTCGGAGGAAATCGTGGACGAGTTAGGCGAGCCGGACGTGATCATCGGCGGGCCACCCTGCGAGCCG
TTCACGGCCGCCAACGCGGAGCGGAAACCTAACCCGCTGGATCGACTCTACGACGACCCCGTCGGCAGGTTGGTGCTCCA
CTTCGTGAGGATTATCGGTGACCTTCAGCCCGAGGTTTTCGTCATGGAGAACGTCCCCGCGATTATGGAGGGGCCCTTGG
AAAAAGCACTGAGGAAAGAGTTCGCACGTGCCGGGTATGATGAGATCCACTTCAACGTACTTCAGGCGGTACATTATGGG
GTCCCTTCGTACCGGCGCCGCGTCTTCATCTCCAACGTGAGGATAGATCCTGAACCCACCGTGGAACGGCCGAAAACCGT
GTGGGACGCTATCGGAGATCTCCCCAGTCCGGATTCGGAGGTGCCCAATCACGAACTGCGCCCGTTGTCCAAGAGGAAGC
TCCGCAGGATCCGTCGCCTTAGGTGGGGGGAGGCCCTGAGCGTCATAAGGGGGGCTAGAGGGAGCTTCAAGAACTGGCTC
AGGTTGCACCCATTCAAGCCAGCCCCTACGGTGATGGGTGGGTCCAGGTTCATACACCCGTTCGAGGACCGACTGCTTAC
CGTTAGGGAGCAAGCCCGGCTGATGAGTTACCCCGACGACCACGTGTTCGAGGGCGGGTACGAGACGCAGTACGACCAGG
TAGGGGAGTCGGTGCCGCCGGAGCTCGCCCGCGTTATCGCCGAGGAAGTCCGTGATCACCTCGCGTAA

Upstream 100 bases:

>100_bases
AACTATGCGATTCGCACGGTCGGAGCAGTCCGACCACTGCCGTTTATTTATGGGGCGTCCGCCGGCGGGTGTTGAGTGAA
ACTCGACTGGGGGTGCCCCG

Downstream 100 bases:

>100_bases
TACAGTAGCGCCGCCACTAACAGACCGATAGCCACGGCGGCTACGATGAGGTACGCCCTAGGTAGCGGAACTCTCGGGAA
CCTCCTGGGTCTCCACTCCT

Product: site-specific DNA methylase

Products: NA

Alternate protein names: Cytosine-specific methyltransferase MJ1200; M.MjaVIIP [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKPKVVDLFCGAGGFSRGFKEAGFKILGGVENNPAPAATYRENFPEAEVIERDIQRVDSEEIVDELGEPDVIIGGPPCEP
FTAANAERKPNPLDRLYDDPVGRLVLHFVRIIGDLQPEVFVMENVPAIMEGPLEKALRKEFARAGYDEIHFNVLQAVHYG
VPSYRRRVFISNVRIDPEPTVERPKTVWDAIGDLPSPDSEVPNHELRPLSKRKLRRIRRLRWGEALSVIRGARGSFKNWL
RLHPFKPAPTVMGGSRFIHPFEDRLLTVREQARLMSYPDDHVFEGGYETQYDQVGESVPPELARVIAEEVRDHLA

Sequences:

>Translated_315_residues
MKPKVVDLFCGAGGFSRGFKEAGFKILGGVENNPAPAATYRENFPEAEVIERDIQRVDSEEIVDELGEPDVIIGGPPCEP
FTAANAERKPNPLDRLYDDPVGRLVLHFVRIIGDLQPEVFVMENVPAIMEGPLEKALRKEFARAGYDEIHFNVLQAVHYG
VPSYRRRVFISNVRIDPEPTVERPKTVWDAIGDLPSPDSEVPNHELRPLSKRKLRRIRRLRWGEALSVIRGARGSFKNWL
RLHPFKPAPTVMGGSRFIHPFEDRLLTVREQARLMSYPDDHVFEGGYETQYDQVGESVPPELARVIAEEVRDHLA
>Mature_315_residues
MKPKVVDLFCGAGGFSRGFKEAGFKILGGVENNPAPAATYRENFPEAEVIERDIQRVDSEEIVDELGEPDVIIGGPPCEP
FTAANAERKPNPLDRLYDDPVGRLVLHFVRIIGDLQPEVFVMENVPAIMEGPLEKALRKEFARAGYDEIHFNVLQAVHYG
VPSYRRRVFISNVRIDPEPTVERPKTVWDAIGDLPSPDSEVPNHELRPLSKRKLRRIRRLRWGEALSVIRGARGSFKNWL
RLHPFKPAPTVMGGSRFIHPFEDRLLTVREQARLMSYPDDHVFEGGYETQYDQVGESVPPELARVIAEEVRDHLA

Specific function: This Methylase Recognizes The Double-Stranded Sequence Ccwgg, Causes Specific Methylation On C-2 On Both Strands. [C]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI195927037, Length=184, Percent_Identity=29.8913043478261, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503351, Length=184, Percent_Identity=29.8913043478261, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788271, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 35692; Mature: 35692

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKVVDLFCGAGGFSRGFKEAGFKILGGVENNPAPAATYRENFPEAEVIERDIQRVDSE
CCCCEEEEEECCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCHH
EIVDELGEPDVIIGGPPCEPFTAANAERKPNPLDRLYDDPVGRLVLHFVRIIGDLQPEVF
HHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCEE
VMENVPAIMEGPLEKALRKEFARAGYDEIHFNVLQAVHYGVPSYRRRVFISNVRIDPEPT
EECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHEEEHCCCEECCCCC
VERPKTVWDAIGDLPSPDSEVPNHELRPLSKRKLRRIRRLRWGEALSVIRGARGSFKNWL
CCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RLHPFKPAPTVMGGSRFIHPFEDRLLTVREQARLMSYPDDHVFEGGYETQYDQVGESVPP
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHCCCCCH
ELARVIAEEVRDHLA
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPKVVDLFCGAGGFSRGFKEAGFKILGGVENNPAPAATYRENFPEAEVIERDIQRVDSE
CCCCEEEEEECCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCHH
EIVDELGEPDVIIGGPPCEPFTAANAERKPNPLDRLYDDPVGRLVLHFVRIIGDLQPEVF
HHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCEE
VMENVPAIMEGPLEKALRKEFARAGYDEIHFNVLQAVHYGVPSYRRRVFISNVRIDPEPT
EECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHEEEHCCCEECCCCC
VERPKTVWDAIGDLPSPDSEVPNHELRPLSKRKLRRIRRLRWGEALSVIRGARGSFKNWL
CCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RLHPFKPAPTVMGGSRFIHPFEDRLLTVREQARLMSYPDDHVFEGGYETQYDQVGESVPP
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHCCCCCH
ELARVIAEEVRDHLA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]