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The map label for this gene is RpoE1 [H]

Identifier: 20094887

GI number: 20094887

Start: 1480832

End: 1481383

Strand: Direct

Name: RpoE1 [H]

Synonym: MK1451

Alternate gene names: 20094887

Gene position: 1480832-1481383 (Clockwise)

Preceding gene: 20094886

Following gene: 20094888

Centisome position: 87.37

GC content: 58.88

Gene sequence:

>552_bases
TTGTACGAGCTCGTGGAACTCGAAACCACGGTTAGAATTCCCCCCACCCAATTTACCTCCGACGTCGAGGATGCCGTGCT
CAAAGCCTTAGAGAACGACGTCGAGGGGAAGCTCTTCCGGGAAGATGACACCGGCGAGCCCATCGGATTCGTGGTCTTCG
TGGACGAAATCCTCGACGTGGAGAATGAGGGTATTTTCCCCGGCGATGGCGCCTCCTACCACCGCGTAAGGTTCAGGGCC
TTGGTCTTCCGCCCGGTGGAGCGCGAGGTGGTAGTGGGCGAAGTAACTAGGGTGAAGGAGTACGGAGCCTTCGTGCGTCT
GGGACCGCTAGACGGTCTCCTGCACGTCTCCCAGATCCTCGATGAGTACATGTACTACGACGGGGCCCGAGAGGCGCTAG
TCGGTGAGGAGACCGGTCGGGAGCTCAAACGGGGTGATGTGATCAAAGTGATGATTATCGGTGTGAGCCTCAACGAGGAA
CGGCCCAGAGACTCGAAGATCGCCTTGACCGTGAAGAGACCCGGTCTAGGGAAGCCGGAGTGGTGGGAATGA

Upstream 100 bases:

>100_bases
CAAGGAGACCGAAGTCCTAGGGTGGGAAGGTGCGGACGCCGCTAAGGAAGCCATAGTTCACGCGATAGAGCTGTACGAGG
AGGAGCACGGGTGAATCCCG

Downstream 100 bases:

>100_bases
CCTCGCCCTGAGCGGGGTTCAGGACGGTCCCTTCCGACTCCATTCAGGACACATCTTTCGTCGCCAACGTTGAAGAGGCC
GGAATCCTCTAACATCCGAG

Product: DNA-directed RNA polymerase subunit E'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MYELVELETTVRIPPTQFTSDVEDAVLKALENDVEGKLFREDDTGEPIGFVVFVDEILDVENEGIFPGDGASYHRVRFRA
LVFRPVEREVVVGEVTRVKEYGAFVRLGPLDGLLHVSQILDEYMYYDGAREALVGEETGRELKRGDVIKVMIIGVSLNEE
RPRDSKIALTVKRPGLGKPEWWE

Sequences:

>Translated_183_residues
MYELVELETTVRIPPTQFTSDVEDAVLKALENDVEGKLFREDDTGEPIGFVVFVDEILDVENEGIFPGDGASYHRVRFRA
LVFRPVEREVVVGEVTRVKEYGAFVRLGPLDGLLHVSQILDEYMYYDGAREALVGEETGRELKRGDVIKVMIIGVSLNEE
RPRDSKIALTVKRPGLGKPEWWE
>Mature_183_residues
MYELVELETTVRIPPTQFTSDVEDAVLKALENDVEGKLFREDDTGEPIGFVVFVDEILDVENEGIFPGDGASYHRVRFRA
LVFRPVEREVVVGEVTRVKEYGAFVRLGPLDGLLHVSQILDEYMYYDGAREALVGEETGRELKRGDVIKVMIIGVSLNEE
RPRDSKIALTVKRPGLGKPEWWE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG1095

COG function: function code K; DNA-directed RNA polymerase, subunit E'

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI24475814, Length=207, Percent_Identity=27.536231884058, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI65301161, Length=207, Percent_Identity=27.536231884058, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322705, Length=135, Percent_Identity=32.5925925925926, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24662815, Length=136, Percent_Identity=32.3529411764706, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR005576
- InterPro:   IPR004519 [H]

Pfam domain/function: PF03876 RNA_pol_Rpb7_N; PF00575 S1 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 20755; Mature: 20755

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYELVELETTVRIPPTQFTSDVEDAVLKALENDVEGKLFREDDTGEPIGFVVFVDEILDV
CCEEEEEEEEEECCCCHHHCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEHHHHCC
ENEGIFPGDGASYHRVRFRALVFRPVEREVVVGEVTRVKEYGAFVRLGPLDGLLHVSQIL
CCCCCCCCCCCCHHHHEEEEEEECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHHHH
DEYMYYDGAREALVGEETGRELKRGDVIKVMIIGVSLNEERPRDSKIALTVKRPGLGKPE
HHHHHCCCCHHHHCCCHHCCHHHCCCEEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCC
WWE
CCC
>Mature Secondary Structure
MYELVELETTVRIPPTQFTSDVEDAVLKALENDVEGKLFREDDTGEPIGFVVFVDEILDV
CCEEEEEEEEEECCCCHHHCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEHHHHCC
ENEGIFPGDGASYHRVRFRALVFRPVEREVVVGEVTRVKEYGAFVRLGPLDGLLHVSQIL
CCCCCCCCCCCCHHHHEEEEEEECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHHHH
DEYMYYDGAREALVGEETGRELKRGDVIKVMIIGVSLNEERPRDSKIALTVKRPGLGKPE
HHHHHCCCCHHHHCCCHHCCHHHCCCEEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCC
WWE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]