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The map label for this gene is CobL_2

Identifier: 20094864

GI number: 20094864

Start: 1457683

End: 1458321

Strand: Direct

Name: CobL_2

Synonym: MK1428

Alternate gene names: NA

Gene position: 1457683-1458321 (Clockwise)

Preceding gene: 20094862

Following gene: 20094865

Centisome position: 86.0

GC content: 60.25

Gene sequence:

>639_bases
GTGCAGGTAGTCGGAGTCGGCCCGAATCCGACGAGGTTTCTGACGATCGAGGCGATCGAACGGATCGCGCGGGCGGATCT
ACTGATCAGTAGTGAGTCGATACTCCGAGAGATCGACGGACTCAGGGTTGAGGCGGAGATAGACCTCTCCGACAAGGAGG
TAGTCACCTGGAACGGTTCCGTTCGGGAGACGCTGACGGAGTACGCGGACAGCGACCCGGTGGTGGTCGCCCGAGGTGAT
CCGACCTACATGGGTGTCGGGAGGCTGGCGTCGTTACTTTTCGACGACGTCGAAATCGTGCCGGGCGTGTCCTCACTGCA
GGCGTTGACGGCCCGGTTCGGTCGGGGCTTTCACGAGGTCGAAGCACACGTCAACCTCCACAGCGAGGAGGACGTTGAAA
AGGTCGTGGAGAGCCTAGGAGCTGGCCGTACCACCGCGGTACTGTTCGGCAAGGTTCGACCGGCGAAAGTCGTCGAGACC
ATCGAGTCGGTGGGCCTAAACGTAAAAGTGATCGCCGGGGAGCGGTTGTGGTACCCGGACGAGCGTCTCGCTACCGAACT
GCACTCGTTACGGAACTTTTCTGAGTTCACGGTGGCGATCTTCGAGCCGGATCACGTGATCGAAACCTCGTTAAGGTAA

Upstream 100 bases:

>100_bases
TGGTGGGGACCTTCCCCTTCGGCTCCGGGACACCCCTCGCAGTGACGTGACGTCGGCAGGCTTAAGCGCGTCACGGTCGA
GGTCCCCCAAGGGGCTTCCG

Downstream 100 bases:

>100_bases
CGATCACGGTGTGAGGGGGGAAGAGACCTTGGCGGAAGTCGTGTTGACGATGGATCGTACGCTGGCCAGCAATTACCGCG
GCGGTATGTTCATGGGGTTC

Product: precorrin-6B methylase

Products: S-adenosyl-L-homocysteine; Precorrin 8X; CO2

Alternate protein names: Precorrin-6y C515-Methyltransferase CbiE Subunit; Precorrin-6B Methylase

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MQVVGVGPNPTRFLTIEAIERIARADLLISSESILREIDGLRVEAEIDLSDKEVVTWNGSVRETLTEYADSDPVVVARGD
PTYMGVGRLASLLFDDVEIVPGVSSLQALTARFGRGFHEVEAHVNLHSEEDVEKVVESLGAGRTTAVLFGKVRPAKVVET
IESVGLNVKVIAGERLWYPDERLATELHSLRNFSEFTVAIFEPDHVIETSLR

Sequences:

>Translated_212_residues
MQVVGVGPNPTRFLTIEAIERIARADLLISSESILREIDGLRVEAEIDLSDKEVVTWNGSVRETLTEYADSDPVVVARGD
PTYMGVGRLASLLFDDVEIVPGVSSLQALTARFGRGFHEVEAHVNLHSEEDVEKVVESLGAGRTTAVLFGKVRPAKVVET
IESVGLNVKVIAGERLWYPDERLATELHSLRNFSEFTVAIFEPDHVIETSLR
>Mature_212_residues
MQVVGVGPNPTRFLTIEAIERIARADLLISSESILREIDGLRVEAEIDLSDKEVVTWNGSVRETLTEYADSDPVVVARGD
PTYMGVGRLASLLFDDVEIVPGVSSLQALTARFGRGFHEVEAHVNLHSEEDVEKVVESLGAGRTTAVLFGKVRPAKVVET
IESVGLNVKVIAGERLWYPDERLATELHSLRNFSEFTVAIFEPDHVIETSLR

Specific function: Unknown

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.132

Molecular weight: Translated: 23353; Mature: 23353

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVVGVGPNPTRFLTIEAIERIARADLLISSESILREIDGLRVEAEIDLSDKEVVTWNGS
CEEEECCCCCCEEEEHHHHHHHHHHHHEECHHHHHHHHCCCEEEEEECCCCCEEEEECCH
VRETLTEYADSDPVVVARGDPTYMGVGRLASLLFDDVEIVPGVSSLQALTARFGRGFHEV
HHHHHHHHCCCCCEEEECCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
EAHVNLHSEEDVEKVVESLGAGRTTAVLFGKVRPAKVVETIESVGLNVKVIAGERLWYPD
HEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCEEECCC
ERLATELHSLRNFSEFTVAIFEPDHVIETSLR
HHHHHHHHHHCCCCCEEEEEECCCHHHHCCCC
>Mature Secondary Structure
MQVVGVGPNPTRFLTIEAIERIARADLLISSESILREIDGLRVEAEIDLSDKEVVTWNGS
CEEEECCCCCCEEEEHHHHHHHHHHHHEECHHHHHHHHCCCEEEEEECCCCCEEEEECCH
VRETLTEYADSDPVVVARGDPTYMGVGRLASLLFDDVEIVPGVSSLQALTARFGRGFHEV
HHHHHHHHCCCCCEEEECCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
EAHVNLHSEEDVEKVVESLGAGRTTAVLFGKVRPAKVVETIESVGLNVKVIAGERLWYPD
HEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCEEECCC
ERLATELHSLRNFSEFTVAIFEPDHVIETSLR
HHHHHHHHHHCCCCCEEEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 6Y

Specific reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA