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The map label for this gene is 20094851

Identifier: 20094851

GI number: 20094851

Start: 1444325

End: 1444906

Strand: Direct

Name: 20094851

Synonym: MK1415

Alternate gene names: NA

Gene position: 1444325-1444906 (Clockwise)

Preceding gene: 20094850

Following gene: 20094853

Centisome position: 85.21

GC content: 59.28

Gene sequence:

>582_bases
GTGGATCTCGATCGGTTGAAGGTAAGTTCCTTCGAGCGCGTAACCCGACCTATCGAGCCGAAGGATTCGGGTCTGATCAC
GGAACGACTGGGGTTACTCCCGGGCCATCGCGTGTTCGAATCGGGCGTCGGATCCGGGTTCCTCACGGCCTCCATGGCCC
GGATAGTCTACCCCGAGGGTGAGGTAGTCGGGATCGAGATCGATACCAGGAAGCTCGAGAAGGCCCGGGAGAACCTCGAG
CAGCTGGGGAAAGTCTACGAAAAGAGCGTGACGTTGAAGCACGGTGACGCTCGGGAGTACCTCGAAGGACTGGAAGACGA
GTTCGATGCGATGGTGTTGGACCTACCCGAGCCCGACCGCGTACTGGAAGTGGGATTGGACGCCCTTAAATCGAACGGGA
AGGTCGCGGTGTTCTGCCCGTTTTTCGAGCAGGTGAGGGCCGTCTGGCAGGTTTTGGAGGATCGATGCACCTGGCTGGAA
GCCGTCGAACTGATCGAGCGAAAACTCCAGGTGGAAAAGCGTGGGATTCGACCCGGTCGTACCCTGGGTCACACGGGGTT
CATAGTCTTCGGTAGGGTCTGA

Upstream 100 bases:

>100_bases
CCGAGCGGGACGTAGTTCGAGAGGCGGTGAAGCGGAACCTTCAGGTCGCCCTAGAGATCGTCGAATCGACGGATCTTCCG
GAGCTCCTGGGGGAATAAGG

Downstream 100 bases:

>100_bases
TTCCTCATCTCGGGACGGTCCACCAGTTCTCCTGGCCTTTTCATGAGCCATAATCAGTCGGGATGTTCGAGGTGGGGAAG
TGGGTCAGAACCGCACGCCC

Product: SAM-dependent methyltransferase involved in tRNA-Met maturation

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MDLDRLKVSSFERVTRPIEPKDSGLITERLGLLPGHRVFESGVGSGFLTASMARIVYPEGEVVGIEIDTRKLEKARENLE
QLGKVYEKSVTLKHGDAREYLEGLEDEFDAMVLDLPEPDRVLEVGLDALKSNGKVAVFCPFFEQVRAVWQVLEDRCTWLE
AVELIERKLQVEKRGIRPGRTLGHTGFIVFGRV

Sequences:

>Translated_193_residues
MDLDRLKVSSFERVTRPIEPKDSGLITERLGLLPGHRVFESGVGSGFLTASMARIVYPEGEVVGIEIDTRKLEKARENLE
QLGKVYEKSVTLKHGDAREYLEGLEDEFDAMVLDLPEPDRVLEVGLDALKSNGKVAVFCPFFEQVRAVWQVLEDRCTWLE
AVELIERKLQVEKRGIRPGRTLGHTGFIVFGRV
>Mature_193_residues
MDLDRLKVSSFERVTRPIEPKDSGLITERLGLLPGHRVFESGVGSGFLTASMARIVYPEGEVVGIEIDTRKLEKARENLE
QLGKVYEKSVTLKHGDAREYLEGLEDEFDAMVLDLPEPDRVLEVGLDALKSNGKVAVFCPFFEQVRAVWQVLEDRCTWLE
AVELIERKLQVEKRGIRPGRTLGHTGFIVFGRV

Specific function: Unknown

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TRM61 family [H]

Homologues:

Organism=Homo sapiens, GI123173772, Length=142, Percent_Identity=33.8028169014084, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 21796; Mature: 21796

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDRLKVSSFERVTRPIEPKDSGLITERLGLLPGHRVFESGVGSGFLTASMARIVYPEG
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCCCC
EVVGIEIDTRKLEKARENLEQLGKVYEKSVTLKHGDAREYLEGLEDEFDAMVLDLPEPDR
CEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEECCCCHH
VLEVGLDALKSNGKVAVFCPFFEQVRAVWQVLEDRCTWLEAVELIERKLQVEKRGIRPGR
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLGHTGFIVFGRV
CCCCCCEEEEECC
>Mature Secondary Structure
MDLDRLKVSSFERVTRPIEPKDSGLITERLGLLPGHRVFESGVGSGFLTASMARIVYPEG
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCCCC
EVVGIEIDTRKLEKARENLEQLGKVYEKSVTLKHGDAREYLEGLEDEFDAMVLDLPEPDR
CEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEECCCCHH
VLEVGLDALKSNGKVAVFCPFFEQVRAVWQVLEDRCTWLEAVELIERKLQVEKRGIRPGR
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLGHTGFIVFGRV
CCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]