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The map label for this gene is SNZ1

Identifier: 20094807

GI number: 20094807

Start: 1399129

End: 1400016

Strand: Reverse

Name: SNZ1

Synonym: MK1371

Alternate gene names: 20094807

Gene position: 1400016-1399129 (Counterclockwise)

Preceding gene: 20094813

Following gene: 20094806

Centisome position: 82.6

GC content: 64.86

Gene sequence:

>888_bases
ATGAAAACCGGTACGTGGCGTGTGAAGACCGGGTTCGCGCGCATGCTGAAAGGAGGCGTCGTGATGGATGTGACCAACGT
CGAGCAGGCTCAGATCGCAGAGGATGCCGGTGCGGTCGCGGTGATGGTGTTGGAGAAGGTCCCTGCGGACATCCGAGCCG
CGGGCGGCGTCGCCCGTATGTGCGACCCCGCCAAGATCGAGGAGATCATGGACCACGTGACCATCCCCGTGATGGCCAAG
TGCAGGATCGGACACGTCGCCGAGGCGCAGGTTCTGGAGGCGATCGGCGTGGACATGATCGACGAGTCGGAGGTCCTCAC
GCCGGCGGACGAGGAACACCACATCAACAAGTGGGAGTTCGAGGTGCCGTTCGTCTGCGGCGCCAGGAACCTGGGTGAGG
CGCTACGTAGGATCGCCGAGGGCGCCGCGATGATCCGGACGAAGGGTGAGGCGGGCACGGGTAACGTCGCCGAGGCCGTC
CGGCACATGAGGATCATCCGGCGCGAGATCTCGGAGCTCACCCGACTGGACAAGGAAGAACTCTACGGGAAGGCGAAGGA
GTACGGGGTGCCGTTCGACCTCGTCGCAGAGGTCGCGAGCCTGGGCAGGCTGCCGGTGGTGAACTTCGCCGCGGGCGGTA
TCGCGACGCCGGCCGACGCCGCCCTGATGATGCAGCTAGGTGCCGACGGAATCTTCGTGGGATCGGGCATCTTCAAGTCG
GATAGACCGCAGGAGATGGCGGAAGCTATCGTCGAAGCGACGGCCTACTACGACGACCCGGAGGTCGTGGCGGAGGTGTC
GAAGAACCTGGGCGACGAGGTGGCCATGCGCGGGCTGGAGATCTCGGAGATCCCGGAAGAGGAGAGGATGCAGCTGCGTG
GTGAGTAA

Upstream 100 bases:

>100_bases
ATCCTCATTACTACCGCTATCTTCCGAAATCATCCAACCCCCTCCGGCGCCCGTGATCGTACTATATAAACCTTCACAAC
AGGTTAATTGGGGGATCCGG

Downstream 100 bases:

>100_bases
CTCCCCCGCTCGGAAACGCGGGTTCCCATCAGGTACGGCGGGTACTGGTTAGATTTAACGGACCGCCTCCGCGTCCGACC
GGGGCGCCGACGTGCTGGGT

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKTGTWRVKTGFARMLKGGVVMDVTNVEQAQIAEDAGAVAVMVLEKVPADIRAAGGVARMCDPAKIEEIMDHVTIPVMAK
CRIGHVAEAQVLEAIGVDMIDESEVLTPADEEHHINKWEFEVPFVCGARNLGEALRRIAEGAAMIRTKGEAGTGNVAEAV
RHMRIIRREISELTRLDKEELYGKAKEYGVPFDLVAEVASLGRLPVVNFAAGGIATPADAALMMQLGADGIFVGSGIFKS
DRPQEMAEAIVEATAYYDDPEVVAEVSKNLGDEVAMRGLEISEIPEEERMQLRGE

Sequences:

>Translated_295_residues
MKTGTWRVKTGFARMLKGGVVMDVTNVEQAQIAEDAGAVAVMVLEKVPADIRAAGGVARMCDPAKIEEIMDHVTIPVMAK
CRIGHVAEAQVLEAIGVDMIDESEVLTPADEEHHINKWEFEVPFVCGARNLGEALRRIAEGAAMIRTKGEAGTGNVAEAV
RHMRIIRREISELTRLDKEELYGKAKEYGVPFDLVAEVASLGRLPVVNFAAGGIATPADAALMMQLGADGIFVGSGIFKS
DRPQEMAEAIVEATAYYDDPEVVAEVSKNLGDEVAMRGLEISEIPEEERMQLRGE
>Mature_295_residues
MKTGTWRVKTGFARMLKGGVVMDVTNVEQAQIAEDAGAVAVMVLEKVPADIRAAGGVARMCDPAKIEEIMDHVTIPVMAK
CRIGHVAEAQVLEAIGVDMIDESEVLTPADEEHHINKWEFEVPFVCGARNLGEALRRIAEGAAMIRTKGEAGTGNVAEAV
RHMRIIRREISELTRLDKEELYGKAKEYGVPFDLVAEVASLGRLPVVNFAAGGIATPADAALMMQLGADGIFVGSGIFKS
DRPQEMAEAIVEATAYYDDPEVVAEVSKNLGDEVAMRGLEISEIPEEERMQLRGE

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6321049, Length=283, Percent_Identity=62.8975265017668, Blast_Score=344, Evalue=9e-96,
Organism=Saccharomyces cerevisiae, GI6323996, Length=283, Percent_Identity=62.5441696113074, Blast_Score=344, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6323743, Length=280, Percent_Identity=61.4285714285714, Blast_Score=342, Evalue=5e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_METKA (Q8TVL8)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614654.1
- ProteinModelPortal:   Q8TVL8
- SMR:   Q8TVL8
- GeneID:   1477966
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1371
- NMPDR:   fig|190192.1.peg.1367
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- BioCyc:   MKAN190192:MK1371-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31918; Mature: 31918

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGTWRVKTGFARMLKGGVVMDVTNVEQAQIAEDAGAVAVMVLEKVPADIRAAGGVARM
CCCCCEEHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHHCCHHHHHCCCHHHC
CDPAKIEEIMDHVTIPVMAKCRIGHVAEAQVLEAIGVDMIDESEVLTPADEEHHINKWEF
CCHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
EVPFVCGARNLGEALRRIAEGAAMIRTKGEAGTGNVAEAVRHMRIIRREISELTRLDKEE
ECCEEECCHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
LYGKAKEYGVPFDLVAEVASLGRLPVVNFAAGGIATPADAALMMQLGADGIFVGSGIFKS
HHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
DRPQEMAEAIVEATAYYDDPEVVAEVSKNLGDEVAMRGLEISEIPEEERMQLRGE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCHHHCCHHHHHHCCCC
>Mature Secondary Structure
MKTGTWRVKTGFARMLKGGVVMDVTNVEQAQIAEDAGAVAVMVLEKVPADIRAAGGVARM
CCCCCEEHHHHHHHHHCCCEEEEECCCHHHHHHHHCCHHHHHHHHHCCHHHHHCCCHHHC
CDPAKIEEIMDHVTIPVMAKCRIGHVAEAQVLEAIGVDMIDESEVLTPADEEHHINKWEF
CCHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
EVPFVCGARNLGEALRRIAEGAAMIRTKGEAGTGNVAEAVRHMRIIRREISELTRLDKEE
ECCEEECCHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
LYGKAKEYGVPFDLVAEVASLGRLPVVNFAAGGIATPADAALMMQLGADGIFVGSGIFKS
HHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
DRPQEMAEAIVEATAYYDDPEVVAEVSKNLGDEVAMRGLEISEIPEEERMQLRGE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014