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The map label for this gene is SelD [H]

Identifier: 20094805

GI number: 20094805

Start: 1397219

End: 1398223

Strand: Reverse

Name: SelD [H]

Synonym: MK1369

Alternate gene names: 20094805

Gene position: 1398223-1397219 (Counterclockwise)

Preceding gene: 20094806

Following gene: 20094803

Centisome position: 82.49

GC content: 67.56

Gene sequence:

>1005_bases
ATGAGTAGAAAGAAGAGCCTCGTCGAGATGGCGGACCTCCACGGATGAGCCTGTAAACTACCCCAGGGAGACCTGGAGGA
TCTGCTGAAGGGCGTCGAGCTGCCGGAGGAAGGCGGGCGCGTGGAGGTCGGTGTCGGCGACGATGCCGCGGTGATCCGCG
TGGACGGCGGCTACGTGATCCAGTCGGTGGACTTCTTCACACCGATACACCCGGACCCGTACACCCAGGGACGGATCGCC
GCGAACAACTCCATCAACGACGTCTTCGCGATGGGAGCCACCGAGGTGCTCTCCGTCCTGGTGGTCTCGGGGTTCCCGAG
GGAGCTCCCGGAGGAGGATGCGCGTGAGATGCTGCAGGGGTTCGCGGACCAGTGCCGCGAAGTGGACGCACTGATCGTCG
GCGGACACACGATTATGAACCCATGGCCCATCCTCGGCGGCTGCGTCACGGGGTTCGCCGAACGGTACGTGACGGTCGGT
GGGGCCGAGCCCGGGGACGTCCTGTACCTCACGAAACCGCTCGGCACACAGCCGGCGATGGCCGCCCTGAGGCTGCCCGA
GGACGTCCGGAAGCAGTTCCTGACGGACTCCGAGCTGGAGGAGGCCGTTGACCTAGCCGTCGAAGTGATGACTGAGCCAC
TCAAGGACGCGGCGGAGGCCGCGCTCGAGGTCGGGGTCCACGCGATGACAGACGTCACCGGGTTCGGGCTCAAGGGGCAC
GCGGGTGAGATGGCGGAGGCCAGCGGCGTCCGCGTGGTCATCGAGCGACTGCCGGTGATCCCGGGGACGACGGAGCTCTC
ACGGGCGCTCGGGTACGGGCTGGAGCGGGGCGAGTCGGCGGAGACGGCCGGGGGGCTTCTGGTCGCGGTGCCGGAGGAAC
ACGCCGAGGACCTGGAGGATGCGTTTGAGCGGCGCGATGTTTGGTACCGACGGATCGGCCGCGTCGAGGAGGGGTCGGGC
GTGGAGGTCCGTGGGGACGTGGAAGAAGTGGAGGATTACCCGTGA

Upstream 100 bases:

>100_bases
TCCCACCGGTACGGTATCGACGCACTTCATAGCCATCAGTATGGCTCCGGGCACGTCTTAAGCCGTGTCATCTATCGGGT
GAGGTCGGGGGTACCGTAGC

Downstream 100 bases:

>100_bases
CCCCGCCGGGGAACCCCGTAGGTGTGGGGACCCGGCGGGGGAGGGCCCGCCACGCGGCGGGCTACTACCTGTGGTATATA
CGGACTGCCCGGCGCTCCCG

Product: selenophosphate synthetase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSRKKSLVEMADLHGUACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQSVDFFTPIHPDPYTQGRIA
ANNSINDVFAMGATEVLSVLVVSGFPRELPEEDAREMLQGFADQCREVDALIVGGHTIMNPWPILGGCVTGFAERYVTVG
GAEPGDVLYLTKPLGTQPAMAALRLPEDVRKQFLTDSELEEAVDLAVEVMTEPLKDAAEAALEVGVHAMTDVTGFGLKGH
AGEMAEASGVRVVIERLPVIPGTTELSRALGYGLERGESAETAGGLLVAVPEEHAEDLEDAFERRDVWYRRIGRVEEGSG
VEVRGDVEEVEDYP

Sequences:

>Translated_334_residues
MSRKKSLVEMADLHG*ACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQSVDFFTPIHPDPYTQGRIA
ANNSINDVFAMGATEVLSVLVVSGFPRELPEEDAREMLQGFADQCREVDALIVGGHTIMNPWPILGGCVTGFAERYVTVG
GAEPGDVLYLTKPLGTQPAMAALRLPEDVRKQFLTDSELEEAVDLAVEVMTEPLKDAAEAALEVGVHAMTDVTGFGLKGH
AGEMAEASGVRVVIERLPVIPGTTELSRALGYGLERGESAETAGGLLVAVPEEHAEDLEDAFERRDVWYRRIGRVEEGSG
VEVRGDVEEVEDYP
>Mature_333_residues
SRKKSLVEMADLHG*ACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQSVDFFTPIHPDPYTQGRIAA
NNSINDVFAMGATEVLSVLVVSGFPRELPEEDAREMLQGFADQCREVDALIVGGHTIMNPWPILGGCVTGFAERYVTVGG
AEPGDVLYLTKPLGTQPAMAALRLPEDVRKQFLTDSELEEAVDLAVEVMTEPLKDAAEAALEVGVHAMTDVTGFGLKGHA
GEMAEASGVRVVIERLPVIPGTTELSRALGYGLERGESAETAGGLLVAVPEEHAEDLEDAFERRDVWYRRIGRVEEGSGV
EVRGDVEEVEDYP

Specific function: Synthesizes selenophosphate from selenide and ATP [H]

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily [H]

Homologues:

Organism=Homo sapiens, GI24797148, Length=320, Percent_Identity=35.625, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI15011844, Length=352, Percent_Identity=34.6590909090909, Blast_Score=161, Evalue=7e-40,
Organism=Escherichia coli, GI1788062, Length=315, Percent_Identity=37.7777777777778, Blast_Score=137, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17543426, Length=311, Percent_Identity=34.4051446945338, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24653602, Length=344, Percent_Identity=34.3023255813954, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24653604, Length=344, Percent_Identity=34.3023255813954, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28574119, Length=311, Percent_Identity=34.4051446945338, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28574118, Length=250, Percent_Identity=35.2, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.9.3 [H]

Molecular weight: Translated: 35751; Mature: 35619

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKKSLVEMADLHGACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQ
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCEEEE
SVDFFTPIHPDPYTQGRIAANNSINDVFAMGATEVLSVLVVSGFPRELPEEDAREMLQGF
EEHHCCCCCCCCCCCCEEECCCCCHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ADQCREVDALIVGGHTIMNPWPILGGCVTGFAERYVTVGGAEPGDVLYLTKPLGTQPAMA
HHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCHHHH
ALRLPEDVRKQFLTDSELEEAVDLAVEVMTEPLKDAAEAALEVGVHAMTDVTGFGLKGHA
HHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GEMAEASGVRVVIERLPVIPGTTELSRALGYGLERGESAETAGGLLVAVPEEHAEDLEDA
CCHHHHCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
FERRDVWYRRIGRVEEGSGVEVRGDVEEVEDYP
HHHHHHHHHHHCCCCCCCCCEEECCHHHHCCCC
>Mature Secondary Structure 
SRKKSLVEMADLHGACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQ
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCEEEE
SVDFFTPIHPDPYTQGRIAANNSINDVFAMGATEVLSVLVVSGFPRELPEEDAREMLQGF
EEHHCCCCCCCCCCCCEEECCCCCHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ADQCREVDALIVGGHTIMNPWPILGGCVTGFAERYVTVGGAEPGDVLYLTKPLGTQPAMA
HHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCHHHH
ALRLPEDVRKQFLTDSELEEAVDLAVEVMTEPLKDAAEAALEVGVHAMTDVTGFGLKGHA
HHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GEMAEASGVRVVIERLPVIPGTTELSRALGYGLERGESAETAGGLLVAVPEEHAEDLEDA
CCHHHHCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
FERRDVWYRRIGRVEEGSGVEVRGDVEEVEDYP
HHHHHHHHHHHCCCCCCCCCEEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]