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The map label for this gene is HmdII

Identifier: 20094801

GI number: 20094801

Start: 1392767

End: 1393741

Strand: Reverse

Name: HmdII

Synonym: MK1365

Alternate gene names: NA

Gene position: 1393741-1392767 (Counterclockwise)

Preceding gene: 20094802

Following gene: 20094798

Centisome position: 82.23

GC content: 67.08

Gene sequence:

>975_bases
TTGGCCACCGTGGCCGTCCTCGGCTTCGGCAACCAGCGCCTGTACGAGAGGATCGGCGCCGCCGAGAAGCTGGGTGGGGA
GCCACCCTTCGGCGGTGCAGCCATGGCGATCGAGTTCGCCGAGGCGGGCCACGACGTCGTACTCGCGGACCCGAACCTGA
GCGAGCAGGACCCCGAGCACGTGGACCGGGTCGCCGACGCCGGTGTTGAGTTGACCGAGGACGACGCCCAGGCCGTCGAA
GGGGCCGAGATGGTCGTCCTGTTCACACCGTTCGGCGCCACCGGTGGCATCATCCGCGAGATAGCCTCGCATCTGGAAGA
AGGGGCCGTCGTTTGTCCCACCTGTACGTCTTCCGCTTTCGAGATTCACGAGAGCCTGTACGAGGCCGGACTGGAGGTGC
CCGAAGCCGTCGGCGTGATGCCCGCACACCCAGCGGGCATCCCGGGCACCGAGAACCACCGGGCCTACATCACCGCCCGG
GGTACGGGCAACGGCACCGTCCTCGCCACGGAGGAGCAGGCGGAGCTCGTCGAGGAGGTATTGTCCTCCACGGGCAAGGA
GGTCTTCGAGCTCCCGCACGTGGAGCTGGTATCGGTGGTCGGCGACCTCAGCGTCGTCCTATTGAAGCGCGTGATCGAGG
CGCTGAAGGAGTTCTGCGCGGTGAAGGCGCTCGGCGCACCGCAGGAGATGATCGACCGCCAGGCCATGATGACCCTCGCG
ACGCTCGCCGCGCTGATCGAGGCTGGCGGGATCGGCGGGCTGCTGGAGACGCTCGACGAGGAGGCGATCGAGGCGTCGTA
CTCGAACATGGAACCGTTCGTCGACGGCGTAGAGGAGCCCGAAGGAGAACCGGTCGAGCGGTTCGTCGTGCTACCGGGCG
AGGCGACACGGGAAGCCGTCATCGAGCTAGTGGGCGAGCGAGGCTGGAGGACGGTGAGAATGAGGGCGTGGGTGGATCTG
TACAAGAAGCACTGA

Upstream 100 bases:

>100_bases
TGCGGGACCGCCTGTGACCCGACCCCAATTTTGACGGCTGACGTTTCCAAACCGTGGCATTTATCATGCTATCCCTGCGG
TCGTGATAAGGGGGTAGCAC

Downstream 100 bases:

>100_bases
AGTTTACTCCTCCAGCCAGATGCCCGGCCTGAGCGGCCGGGCTCCCGCCTTCCTGTCCTCCGGTCCCGGAGCTTCCTCCG
GGTCCGTGTGGATCACCACC

Product: H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein

Products: 5,10-methenyltetrahydromethanopterin; reduced coenzyme F420

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MATVAVLGFGNQRLYERIGAAEKLGGEPPFGGAAMAIEFAEAGHDVVLADPNLSEQDPEHVDRVADAGVELTEDDAQAVE
GAEMVVLFTPFGATGGIIREIASHLEEGAVVCPTCTSSAFEIHESLYEAGLEVPEAVGVMPAHPAGIPGTENHRAYITAR
GTGNGTVLATEEQAELVEEVLSSTGKEVFELPHVELVSVVGDLSVVLLKRVIEALKEFCAVKALGAPQEMIDRQAMMTLA
TLAALIEAGGIGGLLETLDEEAIEASYSNMEPFVDGVEEPEGEPVERFVVLPGEATREAVIELVGERGWRTVRMRAWVDL
YKKH

Sequences:

>Translated_324_residues
MATVAVLGFGNQRLYERIGAAEKLGGEPPFGGAAMAIEFAEAGHDVVLADPNLSEQDPEHVDRVADAGVELTEDDAQAVE
GAEMVVLFTPFGATGGIIREIASHLEEGAVVCPTCTSSAFEIHESLYEAGLEVPEAVGVMPAHPAGIPGTENHRAYITAR
GTGNGTVLATEEQAELVEEVLSSTGKEVFELPHVELVSVVGDLSVVLLKRVIEALKEFCAVKALGAPQEMIDRQAMMTLA
TLAALIEAGGIGGLLETLDEEAIEASYSNMEPFVDGVEEPEGEPVERFVVLPGEATREAVIELVGERGWRTVRMRAWVDL
YKKH
>Mature_323_residues
ATVAVLGFGNQRLYERIGAAEKLGGEPPFGGAAMAIEFAEAGHDVVLADPNLSEQDPEHVDRVADAGVELTEDDAQAVEG
AEMVVLFTPFGATGGIIREIASHLEEGAVVCPTCTSSAFEIHESLYEAGLEVPEAVGVMPAHPAGIPGTENHRAYITARG
TGNGTVLATEEQAELVEEVLSSTGKEVFELPHVELVSVVGDLSVVLLKRVIEALKEFCAVKALGAPQEMIDRQAMMTLAT
LAALIEAGGIGGLLETLDEEAIEASYSNMEPFVDGVEEPEGEPVERFVVLPGEATREAVIELVGERGWRTVRMRAWVDLY
KKH

Specific function: Unknown

COG id: COG4007

COG function: function code R; Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HMD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR010063
- InterPro:   IPR004889
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03201 HMD [H]

EC number: 1.5.99.9

Molecular weight: Translated: 34471; Mature: 34340

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVAVLGFGNQRLYERIGAAEKLGGEPPFGGAAMAIEFAEAGHDVVLADPNLSEQDPEH
CCEEEEEECCCHHHHHHHCHHHHCCCCCCCCCHHEEEEEHHCCCEEEEECCCCCCCCHHH
VDRVADAGVELTEDDAQAVEGAEMVVLFTPFGATGGIIREIASHLEEGAVVCPTCTSSAF
HHHHHHCCCEECCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEECCCCCCHHH
EIHESLYEAGLEVPEAVGVMPAHPAGIPGTENHRAYITARGTGNGTVLATEEQAELVEEV
HHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECHHHHHHHHHH
LSSTGKEVFELPHVELVSVVGDLSVVLLKRVIEALKEFCAVKALGAPQEMIDRQAMMTLA
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TLAALIEAGGIGGLLETLDEEAIEASYSNMEPFVDGVEEPEGEPVERFVVLPGEATREAV
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEECCCCHHHHHH
IELVGERGWRTVRMRAWVDLYKKH
HHHHHCCCCCEEHHHHHHHHHHCC
>Mature Secondary Structure 
ATVAVLGFGNQRLYERIGAAEKLGGEPPFGGAAMAIEFAEAGHDVVLADPNLSEQDPEH
CEEEEEECCCHHHHHHHCHHHHCCCCCCCCCHHEEEEEHHCCCEEEEECCCCCCCCHHH
VDRVADAGVELTEDDAQAVEGAEMVVLFTPFGATGGIIREIASHLEEGAVVCPTCTSSAF
HHHHHHCCCEECCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEECCCCCCHHH
EIHESLYEAGLEVPEAVGVMPAHPAGIPGTENHRAYITARGTGNGTVLATEEQAELVEEV
HHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECHHHHHHHHHH
LSSTGKEVFELPHVELVSVVGDLSVVLLKRVIEALKEFCAVKALGAPQEMIDRQAMMTLA
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TLAALIEAGGIGGLLETLDEEAIEASYSNMEPFVDGVEEPEGEPVERFVVLPGEATREAV
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEECCCCHHHHHH
IELVGERGWRTVRMRAWVDLYKKH
HHHHHCCCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,10-methylenetetrahydromethanopterin; coenzyme F420

Specific reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]