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The map label for this gene is RPS4A

Identifier: 20094656

GI number: 20094656

Start: 1207835

End: 1208617

Strand: Direct

Name: RPS4A

Synonym: MK1220

Alternate gene names: 20094656

Gene position: 1207835-1208617 (Clockwise)

Preceding gene: 20094655

Following gene: 20094657

Centisome position: 71.26

GC content: 64.37

Gene sequence:

>783_bases
TTGGGTCGCGCGCGTAGTGGTCCGAAGCGTCACGTGAAGCGTCTCGCGGCCCCGTACGCCTGGCCGATCCCGAGGAAGGA
AGGTGGTAAGTTCGCACCGAGGCCGTACCCCGGACCGCACACCATGGACACGAGCGTGCCGCTGCTGATCCTGGTACGCG
ACATGCTGGGATACGCCGACTACGCCCGGGAGGCCCGGAAGATCATCACGCGCGGTGAGATCTACGTCGACGGCGTGGTG
AGGAAGGAGCCGAAGTTCCCGGTGGGCATCATGGACGTGGTGGAGATCCCGCGCACCGGGGACAGGTACCGCGTGGTCAT
GAACGAGCACCACCGCCTGGACGTCGTGCCGATCTCCGAAGAGGAGGCCAGGGTGAAGGTCTGCCGGATCAAGAACAAGA
CCTACGTGAGGGGCGGCAACCTCCAGATCACGATGCACGACGGTAAGAACTGGCTCGTCGAGATCGAGGACCCGACGGAC
CCGAAGGAGGATGTCTACAGCGTGGGAGACAGCCTCGTGCTCGAGCTCCCGGAGCCGGACAGCGGTGAGAGCTGGAAGGT
CGTGGATCACATCCCGTTCGAGGAAGGTGTCTGGGTGTACGCGATGACCGGCCGACACTCGGGCGAGGTGGGTCGTGTCG
TCGAGATCCAGACATTCGAGGGTCCGCAGGAGGACCTCATCACCGTCGAGAACCCGGAGGGAGACCAGTTCCAGACCACG
AAGGGCCGGCTCATCGCGATCGGTAAGGACGAGCCGCTGGTCACCGTGAGGAAGGAGGAGTAG

Upstream 100 bases:

>100_bases
GCACCCCCGAGGTCGAGGCCGTACCCGAGAAGTCCGAAGAGGAGAAGGAGGAGAAAGAGAAAGAGGAGGAAAAGTCCGAG
GAGTGAGGGGGTGAACTCGC

Downstream 100 bases:

>100_bases
GGGGAGCTCCCGTTGTCCGTCGTCGACGAGGAGACCCGGCGTAAGATCCTGGAGGACTGGGAGAGCAACCCGATGCGGAA
GCCGCGCGTGGGTAAGGTCA

Product: 30S ribosomal protein S4e

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGRARSGPKRHVKRLAAPYAWPIPRKEGGKFAPRPYPGPHTMDTSVPLLILVRDMLGYADYAREARKIITRGEIYVDGVV
RKEPKFPVGIMDVVEIPRTGDRYRVVMNEHHRLDVVPISEEEARVKVCRIKNKTYVRGGNLQITMHDGKNWLVEIEDPTD
PKEDVYSVGDSLVLELPEPDSGESWKVVDHIPFEEGVWVYAMTGRHSGEVGRVVEIQTFEGPQEDLITVENPEGDQFQTT
KGRLIAIGKDEPLVTVRKEE

Sequences:

>Translated_260_residues
MGRARSGPKRHVKRLAAPYAWPIPRKEGGKFAPRPYPGPHTMDTSVPLLILVRDMLGYADYAREARKIITRGEIYVDGVV
RKEPKFPVGIMDVVEIPRTGDRYRVVMNEHHRLDVVPISEEEARVKVCRIKNKTYVRGGNLQITMHDGKNWLVEIEDPTD
PKEDVYSVGDSLVLELPEPDSGESWKVVDHIPFEEGVWVYAMTGRHSGEVGRVVEIQTFEGPQEDLITVENPEGDQFQTT
KGRLIAIGKDEPLVTVRKEE
>Mature_259_residues
GRARSGPKRHVKRLAAPYAWPIPRKEGGKFAPRPYPGPHTMDTSVPLLILVRDMLGYADYAREARKIITRGEIYVDGVVR
KEPKFPVGIMDVVEIPRTGDRYRVVMNEHHRLDVVPISEEEARVKVCRIKNKTYVRGGNLQITMHDGKNWLVEIEDPTDP
KEDVYSVGDSLVLELPEPDSGESWKVVDHIPFEEGVWVYAMTGRHSGEVGRVVEIQTFEGPQEDLITVENPEGDQFQTTK
GRLIAIGKDEPLVTVRKEE

Specific function: Unknown

COG id: COG1471

COG function: function code J; Ribosomal protein S4E

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain

Homologues:

Organism=Homo sapiens, GI4506725, Length=251, Percent_Identity=31.4741035856574, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI4506727, Length=251, Percent_Identity=31.4741035856574, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI88703062, Length=251, Percent_Identity=30.2788844621514, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17543386, Length=251, Percent_Identity=36.2549800796813, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322605, Length=253, Percent_Identity=32.4110671936759, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6321997, Length=253, Percent_Identity=32.4110671936759, Blast_Score=135, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24663672, Length=253, Percent_Identity=35.5731225296443, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24663668, Length=253, Percent_Identity=35.5731225296443, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RS4E_METKA (Q8TW18)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614503.1
- ProteinModelPortal:   Q8TW18
- GeneID:   1477815
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1220
- NMPDR:   fig|190192.1.peg.1216
- HOGENOM:   HBG392118
- OMA:   RLRECLP
- ProtClustDB:   PRK04313
- BioCyc:   MKAN190192:MK1220-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_00485
- InterPro:   IPR000876
- InterPro:   IPR022994
- InterPro:   IPR013845
- InterPro:   IPR013843
- InterPro:   IPR018199
- InterPro:   IPR002942
- PANTHER:   PTHR11581
- PIRSF:   PIRSF002116
- ProDom:   PD002667
- SMART:   SM00363

Pfam domain/function: PF00900 Ribosomal_S4e; PF08071 RS4NT; PF01479 S4

EC number: NA

Molecular weight: Translated: 29474; Mature: 29343

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00528 RIBOSOMAL_S4E; PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRARSGPKRHVKRLAAPYAWPIPRKEGGKFAPRPYPGPHTMDTSVPLLILVRDMLGYAD
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YAREARKIITRGEIYVDGVVRKEPKFPVGIMDVVEIPRTGDRYRVVMNEHHRLDVVPISE
HHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCEEEEEECCCCEEEEEECCC
EEARVKVCRIKNKTYVRGGNLQITMHDGKNWLVEIEDPTDPKEDVYSVGDSLVLELPEPD
CCCEEEEEEECCCEEEECCCEEEEEECCCEEEEEECCCCCCHHHHHHCCCEEEEECCCCC
SGESWKVVDHIPFEEGVWVYAMTGRHSGEVGRVVEIQTFEGPQEDLITVENPEGDQFQTT
CCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHEEEEECCCCCEEEEC
KGRLIAIGKDEPLVTVRKEE
CCEEEEEECCCCEEEEEECC
>Mature Secondary Structure 
GRARSGPKRHVKRLAAPYAWPIPRKEGGKFAPRPYPGPHTMDTSVPLLILVRDMLGYAD
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YAREARKIITRGEIYVDGVVRKEPKFPVGIMDVVEIPRTGDRYRVVMNEHHRLDVVPISE
HHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCEEEEEECCCCEEEEEECCC
EEARVKVCRIKNKTYVRGGNLQITMHDGKNWLVEIEDPTDPKEDVYSVGDSLVLELPEPD
CCCEEEEEEECCCEEEECCCEEEEEECCCEEEEEECCCCCCHHHHHHCCCEEEEECCCCC
SGESWKVVDHIPFEEGVWVYAMTGRHSGEVGRVVEIQTFEGPQEDLITVENPEGDQFQTT
CCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHEEEEECCCCCEEEEC
KGRLIAIGKDEPLVTVRKEE
CCEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014