Click here to switch to the map view.

The map label for this gene is ychE [C]

Identifier: 20094634

GI number: 20094634

Start: 1192330

End: 1192938

Strand: Direct

Name: ychE [C]

Synonym: MK1198

Alternate gene names: 20094634

Gene position: 1192330-1192938 (Clockwise)

Preceding gene: 20094631

Following gene: 20094635

Centisome position: 70.35

GC content: 66.83

Gene sequence:

>609_bases
CTGGGGTTGGAGGCCTTGGACCCGTACGGCGTGCTCAAGGGCGTGATCGAGCTATTCGTGGTCGTCGATCCCATCGGGAA
CGTGCCGGCGCTCCTCGCGGTCACTTCGGAACTCCGACCCCGGGACCGCGTACGCGTCGTCCACAGGGCTGTCGCCTTCG
CCGCCGTGCTCATCCTCGGCTTCGCGGTCGCCGGCAAGGCCACCCTCGATTATCTCGGGATCTCCGTCGAGGCACTCATG
ATCGCCGGCGGTATCCTCCTGCTCCGCGCCGCCTTCGGGATGGTCGAGGGAGATCCCACGGGCTTCCGCATAGAACCGGG
GTCACACATCGACGTGGCTTATGTCCCCCTCGGAACGCCCCTCCTCGCGGGTCCCGGCGCCATCGTCACCGTGATCGTCA
TGCTCCACCGTCACGGTCGCCTCGAGACGATACTGGCCTGCCTCATCGTCATGCTCCTCACCTTAGTGACCTTCCGAGCC
GCGGAGCGTCTCGCTCGGTTCCTCGGTCGCTCCGGCATCCGAGTCCTCACGCGCGTCATGGGGGTTCTGCTCGCGGCCAT
CGGGGTTCAGATGGTCCTCGACGGCGTCAGCGCCTTCGTACGGGGGTGA

Upstream 100 bases:

>100_bases
CGCCCGGTGCGGCGTCCGTTCGACGCCCTCCTTGATATCACCGCTGCGCAACCGGAAACCCCCCGGCCGACCCCGGGGCG
CGTAGGTTAAACGCTTATGG

Downstream 100 bases:

>100_bases
CCGCGTGCCCGCCAACTTACCCCCCGAGTACCACGAGCTCGAGGAGAAGTACCGGAAGGCCCGCTCCCCCGAGGAGAAGC
TCAGGATCACCGAGGAGATG

Product: MarC family integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MGLEALDPYGVLKGVIELFVVVDPIGNVPALLAVTSELRPRDRVRVVHRAVAFAAVLILGFAVAGKATLDYLGISVEALM
IAGGILLLRAAFGMVEGDPTGFRIEPGSHIDVAYVPLGTPLLAGPGAIVTVIVMLHRHGRLETILACLIVMLLTLVTFRA
AERLARFLGRSGIRVLTRVMGVLLAAIGVQMVLDGVSAFVRG

Sequences:

>Translated_202_residues
MGLEALDPYGVLKGVIELFVVVDPIGNVPALLAVTSELRPRDRVRVVHRAVAFAAVLILGFAVAGKATLDYLGISVEALM
IAGGILLLRAAFGMVEGDPTGFRIEPGSHIDVAYVPLGTPLLAGPGAIVTVIVMLHRHGRLETILACLIVMLLTLVTFRA
AERLARFLGRSGIRVLTRVMGVLLAAIGVQMVLDGVSAFVRG
>Mature_201_residues
GLEALDPYGVLKGVIELFVVVDPIGNVPALLAVTSELRPRDRVRVVHRAVAFAAVLILGFAVAGKATLDYLGISVEALMI
AGGILLLRAAFGMVEGDPTGFRIEPGSHIDVAYVPLGTPLLAGPGAIVTVIVMLHRHGRLETILACLIVMLLTLVTFRAA
ERLARFLGRSGIRVLTRVMGVLLAAIGVQMVLDGVSAFVRG

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=201, Percent_Identity=30.8457711442786, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789842, Length=198, Percent_Identity=28.7878787878788, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787809, Length=199, Percent_Identity=24.6231155778894, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 21296; Mature: 21165

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLEALDPYGVLKGVIELFVVVDPIGNVPALLAVTSELRPRDRVRVVHRAVAFAAVLILG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FAVAGKATLDYLGISVEALMIAGGILLLRAAFGMVEGDPTGFRIEPGSHIDVAYVPLGTP
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCC
LLAGPGAIVTVIVMLHRHGRLETILACLIVMLLTLVTFRAAERLARFLGRSGIRVLTRVM
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GVLLAAIGVQMVLDGVSAFVRG
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLEALDPYGVLKGVIELFVVVDPIGNVPALLAVTSELRPRDRVRVVHRAVAFAAVLILG
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FAVAGKATLDYLGISVEALMIAGGILLLRAAFGMVEGDPTGFRIEPGSHIDVAYVPLGTP
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCC
LLAGPGAIVTVIVMLHRHGRLETILACLIVMLLTLVTFRAAERLARFLGRSGIRVLTRVM
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GVLLAAIGVQMVLDGVSAFVRG
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]