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The map label for this gene is apgM

Identifier: 20094629

GI number: 20094629

Start: 1187747

End: 1189015

Strand: Direct

Name: apgM

Synonym: MK1193

Alternate gene names: 20094629

Gene position: 1187747-1189015 (Clockwise)

Preceding gene: 20094628

Following gene: 20094630

Centisome position: 70.07

GC content: 67.45

Gene sequence:

>1269_bases
CTGAGGGTGACCGGATTGGAGAGGAAGATCCTGGTGATCGTAGGAGACGGAATGGCGGATCGAGCCGTGCCCGAGCTCGA
CGGAAAGACCCCGCTCCAGGCCGCAGACACCCCGAACATGGATCGGCTCGCGAGGGAAGGGTCGGTGGGTCTGCTCGACC
CGATCCGGCCCGGAGTGCGCCCGGGTAGCGACACCGCACACCTCACCCTGCTCGGTTACGACCCGTTCGAGGTCTACCCG
GGACGCGGCCCGCTGGAGGCCCTGGGTGCGGGTGTCGAGGTGAGACCGGGCGACGTGGCCTTCCGCTGCAACTTCGCGAC
GGCCGAGGAGCGGAACGGCGAGTTGGTCGTTGTGGACCGTAGAGCCGGTCGGATCAACGAGGACGAGGGTACTCCAAAGC
TGGCCGAGACTATCAACGAAGAAGTCGATCTCCCGGTCGAGTTCGAGTTCAAGGAGGCCGTCGGTCACAGGGCCGTCCTG
GTACTGCGAGGCGGCGACCTCTCCGCCGATGTCACGGACGCTGACCCTAAGCGTGTCGGCAAGCCCGTGAAGGACGTGAA
ACCGACCTCGGACGACCCGGCGGCCGCCCGGACGGCGGAGATCGTCAACGAGTTCGTCCGTAAGGCGTACGAGGTGCTAA
AGGATCACCCGGTCAACCGGGAGCGGGAGCGACAGGGTAAGCCGCCGGCGAACGTGATTCTCCCACGCGGAGCCGGCCAG
CTCGAGGAGGTCGAGCCGTTCTCGGACCGCTACGGCATGAGCGGGGCCGTGGTCGCGGGTGCGTCCCTGATCAAGGGAAT
CGGCCGGATGCTGGGGATGGACGTGCCCGAGGACGAGGCGATCACGGGTCGTAAGGACACCGACCTGAAGAGGAAGGCCG
AGCTCGCGCTGGAGGCCCTGGACGACCACGACCTCGTGCTCGTCAACTTCAACGCCGTGGACGAGGCTGGGCACGACGGT
GATGCCCGCGGTAAGGTCGAGATGATCGAACGGATGGACCGGGAGCTGGTGGGCACGCTCCTGGAGGGGATAGATCCGGA
GGAGACGGTGGTGTGCCTGACCGCCGACCACTCGACGCCGGTGGCCGTCGGTGATCACACGGCCGATCCCGTGCCCGTGG
CGATCTGGACCGCGGACGCGCGACGTGACCCCGTGGAGGAGTACGACGAGATCTCGGCGGCCCGAGGGTGCCTCGGGCGC
TTCTCGGGGCTCCACCTGCTGAACGTGCTCCGGGACCTGGCCGACCGCATCGAGAAGTTCGGGGCGTAG

Upstream 100 bases:

>100_bases
CGAGAGTCGGCGGTCGGAGGCCCCGCACCCCTCGGACTTCACGATGATCCGATGATGTGCTTACAGCACGCCGAACATTC
CGTGACGACCACGGGAGCGG

Downstream 100 bases:

>100_bases
TCGGATGTCGATCACGGAGACGCTCGTGGCCTACTTCATGGACTTCGAGCGGGCCATGGGTCTGCCAGGGATGCTCGTGA
TCACCGCCCTGGAGTGTAGC

Product: cofactor-independent phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; aPGAM

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MRVTGLERKILVIVGDGMADRAVPELDGKTPLQAADTPNMDRLAREGSVGLLDPIRPGVRPGSDTAHLTLLGYDPFEVYP
GRGPLEALGAGVEVRPGDVAFRCNFATAEERNGELVVVDRRAGRINEDEGTPKLAETINEEVDLPVEFEFKEAVGHRAVL
VLRGGDLSADVTDADPKRVGKPVKDVKPTSDDPAAARTAEIVNEFVRKAYEVLKDHPVNRERERQGKPPANVILPRGAGQ
LEEVEPFSDRYGMSGAVVAGASLIKGIGRMLGMDVPEDEAITGRKDTDLKRKAELALEALDDHDLVLVNFNAVDEAGHDG
DARGKVEMIERMDRELVGTLLEGIDPEETVVCLTADHSTPVAVGDHTADPVPVAIWTADARRDPVEEYDEISAARGCLGR
FSGLHLLNVLRDLADRIEKFGA

Sequences:

>Translated_422_residues
MRVTGLERKILVIVGDGMADRAVPELDGKTPLQAADTPNMDRLAREGSVGLLDPIRPGVRPGSDTAHLTLLGYDPFEVYP
GRGPLEALGAGVEVRPGDVAFRCNFATAEERNGELVVVDRRAGRINEDEGTPKLAETINEEVDLPVEFEFKEAVGHRAVL
VLRGGDLSADVTDADPKRVGKPVKDVKPTSDDPAAARTAEIVNEFVRKAYEVLKDHPVNRERERQGKPPANVILPRGAGQ
LEEVEPFSDRYGMSGAVVAGASLIKGIGRMLGMDVPEDEAITGRKDTDLKRKAELALEALDDHDLVLVNFNAVDEAGHDG
DARGKVEMIERMDRELVGTLLEGIDPEETVVCLTADHSTPVAVGDHTADPVPVAIWTADARRDPVEEYDEISAARGCLGR
FSGLHLLNVLRDLADRIEKFGA
>Mature_422_residues
MRVTGLERKILVIVGDGMADRAVPELDGKTPLQAADTPNMDRLAREGSVGLLDPIRPGVRPGSDTAHLTLLGYDPFEVYP
GRGPLEALGAGVEVRPGDVAFRCNFATAEERNGELVVVDRRAGRINEDEGTPKLAETINEEVDLPVEFEFKEAVGHRAVL
VLRGGDLSADVTDADPKRVGKPVKDVKPTSDDPAAARTAEIVNEFVRKAYEVLKDHPVNRERERQGKPPANVILPRGAGQ
LEEVEPFSDRYGMSGAVVAGASLIKGIGRMLGMDVPEDEAITGRKDTDLKRKAELALEALDDHDLVLVNFNAVDEAGHDG
DARGKVEMIERMDRELVGTLLEGIDPEETVVCLTADHSTPVAVGDHTADPVPVAIWTADARRDPVEEYDEISAARGCLGR
FSGLHLLNVLRDLADRIEKFGA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG3635

COG function: function code G; Predicted phosphoglycerate mutase, AP superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APGM_METKA (P58813)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614476.1
- ProteinModelPortal:   P58813
- SMR:   P58813
- GeneID:   1477294
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1193
- NMPDR:   fig|190192.1.peg.1189
- HOGENOM:   HBG463247
- OMA:   INIERRE
- ProtClustDB:   PRK04024
- BioCyc:   MKAN190192:MK1193-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01402_A
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR004456
- InterPro:   IPR006124
- Gene3D:   G3DSA:3.40.720.10
- PIRSF:   PIRSF006392
- TIGRFAMs:   TIGR00306

Pfam domain/function: PF01676 Metalloenzyme; PF10143 PhosphMutase; SSF53649 Alkaline_phosphatase_core

EC number: =5.4.2.1

Molecular weight: Translated: 45626; Mature: 45626

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTGLERKILVIVGDGMADRAVPELDGKTPLQAADTPNMDRLAREGSVGLLDPIRPGVR
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
PGSDTAHLTLLGYDPFEVYPGRGPLEALGAGVEVRPGDVAFRCNFATAEERNGELVVVDR
CCCCCEEEEEEECCCCEECCCCCCHHHHCCCCEECCCCEEEEEECCCCCCCCCCEEEEEC
RAGRINEDEGTPKLAETINEEVDLPVEFEFKEAVGHRAVLVLRGGDLSADVTDADPKRVG
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHCCCEEEEEEECCCCCCCCCCCCHHHHC
KPVKDVKPTSDDPAAARTAEIVNEFVRKAYEVLKDHPVNRERERQGKPPANVILPRGAGQ
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEECCCCC
LEEVEPFSDRYGMSGAVVAGASLIKGIGRMLGMDVPEDEAITGRKDTDLKRKAELALEAL
CHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
DDHDLVLVNFNAVDEAGHDGDARGKVEMIERMDRELVGTLLEGIDPEETVVCLTADHSTP
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
VAVGDHTADPVPVAIWTADARRDPVEEYDEISAARGCLGRFSGLHLLNVLRDLADRIEKF
EEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GA
CC
>Mature Secondary Structure
MRVTGLERKILVIVGDGMADRAVPELDGKTPLQAADTPNMDRLAREGSVGLLDPIRPGVR
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
PGSDTAHLTLLGYDPFEVYPGRGPLEALGAGVEVRPGDVAFRCNFATAEERNGELVVVDR
CCCCCEEEEEEECCCCEECCCCCCHHHHCCCCEECCCCEEEEEECCCCCCCCCCEEEEEC
RAGRINEDEGTPKLAETINEEVDLPVEFEFKEAVGHRAVLVLRGGDLSADVTDADPKRVG
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHCCCEEEEEEECCCCCCCCCCCCHHHHC
KPVKDVKPTSDDPAAARTAEIVNEFVRKAYEVLKDHPVNRERERQGKPPANVILPRGAGQ
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEECCCCC
LEEVEPFSDRYGMSGAVVAGASLIKGIGRMLGMDVPEDEAITGRKDTDLKRKAELALEAL
CHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
DDHDLVLVNFNAVDEAGHDGDARGKVEMIERMDRELVGTLLEGIDPEETVVCLTADHSTP
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
VAVGDHTADPVPVAIWTADARRDPVEEYDEISAARGCLGRFSGLHLLNVLRDLADRIEKF
EEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014