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The map label for this gene is 20094212

Identifier: 20094212

GI number: 20094212

Start: 736523

End: 737884

Strand: Reverse

Name: 20094212

Synonym: MK0775

Alternate gene names: NA

Gene position: 737884-736523 (Counterclockwise)

Preceding gene: 20094213

Following gene: 20094211

Centisome position: 43.53

GC content: 53.01

Gene sequence:

>1362_bases
GTGGAACCGTTGACCGTCGAGGTGTTCGCAGTAGGGGGATACGGCGAGGCCGGTGGACGAAACATGACCGCGGTCCGCGT
GGACGAGGAGATAGTGATCTTCGACTGTGGTATGTCCCTGGACAAATCACTAGTTTTCGAAAAAGATTTTCAGAAAGCCT
CAGCCAGGGAACTCCGTAGAGTGAAAGCGATACCGAACGACCCTATCTTACGCCCCCATCGTTCCAAGACGGTCGCCGCG
GTCCTGTCCCACGCTCACTTAGACCACATCGGAGCGGTACCTAAGCTGCTCTTTAAGTACAAGTGCCCGGTATTCGGAAC
TGAGTTCACAATAGAACTCGTGAAAGCCGACCTCAGGAATGAGATAAGGTACGCAGATGAAGCCGAAGATATCATGATTA
ACTTGTACACAGTCGAGCCTGGAGACGAAGTGCAGATCTCCTCGAAACTCCGACTTGAATTTATCCCTATAAGCCACAGC
ATACCGTGCTGTGTCCTACCAGTGTTGCATACTCCCTACGGAGCAATAGTATATGCGTGCGATTTTAAGTTCGATGATAA
TCAAATAATAGGATACAAACCGGATTATAAAAGGCTCAAACAGCTGGGCAAAGAAGGTGTGTTACTGCTCATTACTGAGA
GTTTGAGGGTCGCTGAAGAAATTAAGACACCTTCCGAATCTGTAGCTAGGGAAATGGTAAACGACGTGCTCAGATTCGCC
GACGAGGAAAGTGAGGGGATTATCGTTACAACGTTCTCGTCACACATAGAACGGATACAGGCGATCGCAGACACTGCGGA
CAGATTAGGCAGGAAAGTGATCCTCGCCGGAAGATCCATGGGCAAATACGGGAGGATCGCCGAAGAGCTCGGTCTCCTGA
ACCTCCCCGCGGGTGCCAGGATTTACGATCGCCCCGAGACTATTCGGCGGGGACTCGAACGGGCGAACAAGGAGAAGGAG
GATTACCTACTGATCGTCACGGGACACCAGGGAGAGCCGGGCGCCGTGTTACCGCGGATCGTTGACGGCGAGCTCCCGTA
CCGACTGACCGAAGAAGATAGCGTAGTGTTCTCGTCGTCCACAATTCCGTCCCCTATAAATCGAGCCAACCGCTACGTGT
TGGACACCAAGCTCCGGCTGAAGGGTGTGAAAATGTTCAAGGACGTGCACGTGTCAGGGCACGCGGGTCGTGAAGACCAT
CGCCTAATGCTCAGAATGCTCCAGCCGGAGTTCATCGTCCCGGCACACGGTGACCCGGATATGCTGGCCGCGTACGCCGA
ACTGGCCACTCAGGAGGGTTACGAGGTGAACCGAGACGTATTCATAATGTTCGACGGCACGAAGCTAAGTCTGCCGTTAT
AA

Upstream 100 bases:

>100_bases
TGAGCAGCGTCCCCATAGTAGTGTACGGGAAGCTGCGTGAGTGGTTGGAGTGCCGGGGAGTCCCACTCGATCTCGTCTGC
ACCGGTGATCGCCGAACGGG

Downstream 100 bases:

>100_bases
GGGGACGATTCCATGCGGAGTGAGATACTGAAAGAGCTGAACCGTGCACGCGAGCTCGTCGACGCCAAGATTGAGGAGGT
ACTACCCAGAGGAGGCCCAG

Product: metallo-beta-lactamase superfamily hydrolase

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MEPLTVEVFAVGGYGEAGGRNMTAVRVDEEIVIFDCGMSLDKSLVFEKDFQKASARELRRVKAIPNDPILRPHRSKTVAA
VLSHAHLDHIGAVPKLLFKYKCPVFGTEFTIELVKADLRNEIRYADEAEDIMINLYTVEPGDEVQISSKLRLEFIPISHS
IPCCVLPVLHTPYGAIVYACDFKFDDNQIIGYKPDYKRLKQLGKEGVLLLITESLRVAEEIKTPSESVAREMVNDVLRFA
DEESEGIIVTTFSSHIERIQAIADTADRLGRKVILAGRSMGKYGRIAEELGLLNLPAGARIYDRPETIRRGLERANKEKE
DYLLIVTGHQGEPGAVLPRIVDGELPYRLTEEDSVVFSSSTIPSPINRANRYVLDTKLRLKGVKMFKDVHVSGHAGREDH
RLMLRMLQPEFIVPAHGDPDMLAAYAELATQEGYEVNRDVFIMFDGTKLSLPL

Sequences:

>Translated_453_residues
MEPLTVEVFAVGGYGEAGGRNMTAVRVDEEIVIFDCGMSLDKSLVFEKDFQKASARELRRVKAIPNDPILRPHRSKTVAA
VLSHAHLDHIGAVPKLLFKYKCPVFGTEFTIELVKADLRNEIRYADEAEDIMINLYTVEPGDEVQISSKLRLEFIPISHS
IPCCVLPVLHTPYGAIVYACDFKFDDNQIIGYKPDYKRLKQLGKEGVLLLITESLRVAEEIKTPSESVAREMVNDVLRFA
DEESEGIIVTTFSSHIERIQAIADTADRLGRKVILAGRSMGKYGRIAEELGLLNLPAGARIYDRPETIRRGLERANKEKE
DYLLIVTGHQGEPGAVLPRIVDGELPYRLTEEDSVVFSSSTIPSPINRANRYVLDTKLRLKGVKMFKDVHVSGHAGREDH
RLMLRMLQPEFIVPAHGDPDMLAAYAELATQEGYEVNRDVFIMFDGTKLSLPL
>Mature_453_residues
MEPLTVEVFAVGGYGEAGGRNMTAVRVDEEIVIFDCGMSLDKSLVFEKDFQKASARELRRVKAIPNDPILRPHRSKTVAA
VLSHAHLDHIGAVPKLLFKYKCPVFGTEFTIELVKADLRNEIRYADEAEDIMINLYTVEPGDEVQISSKLRLEFIPISHS
IPCCVLPVLHTPYGAIVYACDFKFDDNQIIGYKPDYKRLKQLGKEGVLLLITESLRVAEEIKTPSESVAREMVNDVLRFA
DEESEGIIVTTFSSHIERIQAIADTADRLGRKVILAGRSMGKYGRIAEELGLLNLPAGARIYDRPETIRRGLERANKEKE
DYLLIVTGHQGEPGAVLPRIVDGELPYRLTEEDSVVFSSSTIPSPINRANRYVLDTKLRLKGVKMFKDVHVSGHAGREDH
RLMLRMLQPEFIVPAHGDPDMLAAYAELATQEGYEVNRDVFIMFDGTKLSLPL

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 50761; Mature: 50761

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00216 SUGAR_TRANSPORT_1 ; PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLTVEVFAVGGYGEAGGRNMTAVRVDEEIVIFDCGMSLDKSLVFEKDFQKASARELRR
CCCEEEEEEEECCCCCCCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VKAIPNDPILRPHRSKTVAAVLSHAHLDHIGAVPKLLFKYKCPVFGTEFTIELVKADLRN
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
EIRYADEAEDIMINLYTVEPGDEVQISSKLRLEFIPISHSIPCCVLPVLHTPYGAIVYAC
HHCCCCCCCEEEEEEEEECCCCCEEEECEEEEEEEECCCCCCCEEHHHHHCCCCEEEEEE
DFKFDDNQIIGYKPDYKRLKQLGKEGVLLLITESLRVAEEIKTPSESVAREMVNDVLRFA
EEEECCCEEECCCCCHHHHHHCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHC
DEESEGIIVTTFSSHIERIQAIADTADRLGRKVILAGRSMGKYGRIAEELGLLNLPAGAR
CCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCEECCCCCE
IYDRPETIRRGLERANKEKEDYLLIVTGHQGEPGAVLPRIVDGELPYRLTEEDSVVFSSS
ECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCEEECCCCCEEEECC
TIPSPINRANRYVLDTKLRLKGVKMFKDVHVSGHAGREDHRLMLRMLQPEFIVPAHGDPD
CCCCCHHHCCCEEEEEEEEHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCEEEECCCCHH
MLAAYAELATQEGYEVNRDVFIMFDGTKLSLPL
HHHHHHHHHHCCCCCCCCEEEEEECCCEEECCC
>Mature Secondary Structure
MEPLTVEVFAVGGYGEAGGRNMTAVRVDEEIVIFDCGMSLDKSLVFEKDFQKASARELRR
CCCEEEEEEEECCCCCCCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VKAIPNDPILRPHRSKTVAAVLSHAHLDHIGAVPKLLFKYKCPVFGTEFTIELVKADLRN
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
EIRYADEAEDIMINLYTVEPGDEVQISSKLRLEFIPISHSIPCCVLPVLHTPYGAIVYAC
HHCCCCCCCEEEEEEEEECCCCCEEEECEEEEEEEECCCCCCCEEHHHHHCCCCEEEEEE
DFKFDDNQIIGYKPDYKRLKQLGKEGVLLLITESLRVAEEIKTPSESVAREMVNDVLRFA
EEEECCCEEECCCCCHHHHHHCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHC
DEESEGIIVTTFSSHIERIQAIADTADRLGRKVILAGRSMGKYGRIAEELGLLNLPAGAR
CCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCEECCCCCE
IYDRPETIRRGLERANKEKEDYLLIVTGHQGEPGAVLPRIVDGELPYRLTEEDSVVFSSS
ECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCEEECCCCCEEEECC
TIPSPINRANRYVLDTKLRLKGVKMFKDVHVSGHAGREDHRLMLRMLQPEFIVPAHGDPD
CCCCCHHHCCCEEEEEEEEHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCEEEECCCCHH
MLAAYAELATQEGYEVNRDVFIMFDGTKLSLPL
HHHHHHHHHHCCCCCCCCEEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]