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The map label for this gene is 20094101

Identifier: 20094101

GI number: 20094101

Start: 621086

End: 622561

Strand: Reverse

Name: 20094101

Synonym: MK0663

Alternate gene names: NA

Gene position: 622561-621086 (Counterclockwise)

Preceding gene: 20094107

Following gene: 20094088

Centisome position: 36.73

GC content: 64.43

Gene sequence:

>1476_bases
GTGCTACCAACGCCCGGGGTGCCGAGGTTGGAGCTCGAAGAGGAGCTCCGGAAACACGTCCCCGACGAGGCGAAGGAGTT
CGTGCGGAGTGTGTTGAGTCGGTTACTCGCGTGCGAACGGGAGATCGACCGTACGCTGGAGGCCCTGGACGGATGCTACG
TCGAGCCTGGACCGGCCGGTAACCCGACCCGTGGGGACGTCGACGTCCTTCCCACGGGGAAGAACTTCTACTCCGTAGAC
CCGCGGAAGGTCCCGACCCGCAGGGCATGGAAGGTCGGGAAGAAGTTGGCCGAGAACACCATCGAGAGGTACCTGGAGGA
GCACGGACGCTACCCGGAGTCCGTCGGTATCGTGCTGTGGGCGTCGGACGTGATGCGAACCGGCGGAGAGGTTCTATCCC
AGGTGATGTGGCTCCTGGGCGTGAGACCCGAGTGGGACGAATCCGGTATCGTGAGCGGCTTCGAGGTAGTGCCGTTGGAG
GAGCTGGAACGGCCCCGGATCGACGTGGTGGTGAGGATAAGCGGAATGTTTCGTGATGCGTTCCCGAACCTGGTGAAGTT
CCTCGACGAGGTATTCGAGGCCGTGAGGGAGTTGGACGAACCGGAAGGGTGGAACTTCGTCAGGAAGCACGCCCTCGACC
ATCGCATCTTCGGGGATCCACCGGGAGCGTACGGGGCCGGGGTGAACTACGCCGTACACGCCTCCGCATGGGACGACAGA
TCCGATCTCGCGGACGTGTACGTGCGGTGGGGTGGGTACGCCTACGGCAGTGACGTGTACGGTGAGGAGGCCTTCTCCGA
GTTCCGACGGGCGCTCTCGACCGTGAGGGCCGTCTCCGTCAACCAGTCCTCGCACGAGTGGGATGTGCTGAGCTGCTGCT
GCCATTTCGCGTTCCACGGGGGGATGGTGGCGGCCGCCGAGCACCACTCGGGCGAGCGTGTGGAGTGCTACCACCACGAC
ACGACGGACCCGCATAGGGTGATCACGAGACCCATCGAGGAGGAGCTGGTGCGGCTCGTGGAGCAGAAGCTGGCGAACGA
CGAGTGGATCGAGGCCATGCTGGAGCACGGGGCCAAGGGCGTGGGCGAGTGGCTTAAGCGCGTGGAAAATCTGTTCGGCT
GGGATGCGACCACGGGTCGCGTCCCGAGCGAGTGTTACGAGAAAATCGAGGATGTTCTGGAGCGGTACGGTCCGAGGTTC
TCGGACGAGAATCCGTACGCGGTCGAGTACGCCCGGGAGAGACTGTTGGAAGCGAAAAAAACGGGGTCTGTGGCGTTAGC
GGACGATGTTGGCCGGGTGCTCCTCCACCTGCGGCTCGACGCCGACGTCCTCGTTGGCCTCGACGATCAGCGCGTCGACC
ATGGCGACGACCGGCCAGATCGCCGGCGCGTTCTCGATCGGACCGAACAGCAGGTAGTCGCAGCACAGCGTCGCCGCCAC
TACGTTGGAGCCCCAGTCGGAGGACTCGTGGGCTAG

Upstream 100 bases:

>100_bases
CGACGTCTCGGGCGGCTTTCAACATCGTGCCGGAGCATACGCACAGGACTCGCAACGGTGATCCCCGAACACTTATTCTG
TATTACCTTGAATCGCTTTC

Downstream 100 bases:

>100_bases
CTCGGCCCACTCTTCCTTGCCTTCCTCCTTGAGCTTCTTCATGAAGTCACGTAGCCAGTCCCAAGCGGACGGCACGTTGT
GGGGCGCACCGCCCACCGGC

Product: hypothetical protein

Products: ADP; phosphate; cob(II)yrinic acid a,c-diamide; H+

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MLPTPGVPRLELEEELRKHVPDEAKEFVRSVLSRLLACEREIDRTLEALDGCYVEPGPAGNPTRGDVDVLPTGKNFYSVD
PRKVPTRRAWKVGKKLAENTIERYLEEHGRYPESVGIVLWASDVMRTGGEVLSQVMWLLGVRPEWDESGIVSGFEVVPLE
ELERPRIDVVVRISGMFRDAFPNLVKFLDEVFEAVRELDEPEGWNFVRKHALDHRIFGDPPGAYGAGVNYAVHASAWDDR
SDLADVYVRWGGYAYGSDVYGEEAFSEFRRALSTVRAVSVNQSSHEWDVLSCCCHFAFHGGMVAAAEHHSGERVECYHHD
TTDPHRVITRPIEEELVRLVEQKLANDEWIEAMLEHGAKGVGEWLKRVENLFGWDATTGRVPSECYEKIEDVLERYGPRF
SDENPYAVEYARERLLEAKKTGSVALADDVGRVLLHLRLDADVLVGLDDQRVDHGDDRPDRRRVLDRTEQQVVAAQRRRH
YVGAPVGGLVG

Sequences:

>Translated_491_residues
MLPTPGVPRLELEEELRKHVPDEAKEFVRSVLSRLLACEREIDRTLEALDGCYVEPGPAGNPTRGDVDVLPTGKNFYSVD
PRKVPTRRAWKVGKKLAENTIERYLEEHGRYPESVGIVLWASDVMRTGGEVLSQVMWLLGVRPEWDESGIVSGFEVVPLE
ELERPRIDVVVRISGMFRDAFPNLVKFLDEVFEAVRELDEPEGWNFVRKHALDHRIFGDPPGAYGAGVNYAVHASAWDDR
SDLADVYVRWGGYAYGSDVYGEEAFSEFRRALSTVRAVSVNQSSHEWDVLSCCCHFAFHGGMVAAAEHHSGERVECYHHD
TTDPHRVITRPIEEELVRLVEQKLANDEWIEAMLEHGAKGVGEWLKRVENLFGWDATTGRVPSECYEKIEDVLERYGPRF
SDENPYAVEYARERLLEAKKTGSVALADDVGRVLLHLRLDADVLVGLDDQRVDHGDDRPDRRRVLDRTEQQVVAAQRRRH
YVGAPVGGLVG
>Mature_491_residues
MLPTPGVPRLELEEELRKHVPDEAKEFVRSVLSRLLACEREIDRTLEALDGCYVEPGPAGNPTRGDVDVLPTGKNFYSVD
PRKVPTRRAWKVGKKLAENTIERYLEEHGRYPESVGIVLWASDVMRTGGEVLSQVMWLLGVRPEWDESGIVSGFEVVPLE
ELERPRIDVVVRISGMFRDAFPNLVKFLDEVFEAVRELDEPEGWNFVRKHALDHRIFGDPPGAYGAGVNYAVHASAWDDR
SDLADVYVRWGGYAYGSDVYGEEAFSEFRRALSTVRAVSVNQSSHEWDVLSCCCHFAFHGGMVAAAEHHSGERVECYHHD
TTDPHRVITRPIEEELVRLVEQKLANDEWIEAMLEHGAKGVGEWLKRVENLFGWDATTGRVPSECYEKIEDVLERYGPRF
SDENPYAVEYARERLLEAKKTGSVALADDVGRVLLHLRLDADVLVGLDDQRVDHGDDRPDRRRVLDRTEQQVVAAQRRRH
YVGAPVGGLVG

Specific function: Unknown

COG id: COG1429

COG function: function code H; Cobalamin biosynthesis protein CobN and related Mg-chelatases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunit H family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003672 [H]

Pfam domain/function: PF02514 CobN-Mg_chel [H]

EC number: 6.6.1.2

Molecular weight: Translated: 55590; Mature: 55590

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPTPGVPRLELEEELRKHVPDEAKEFVRSVLSRLLACEREIDRTLEALDGCYVEPGPAG
CCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NPTRGDVDVLPTGKNFYSVDPRKVPTRRAWKVGKKLAENTIERYLEEHGRYPESVGIVLW
CCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ASDVMRTGGEVLSQVMWLLGVRPEWDESGIVSGFEVVPLEELERPRIDVVVRISGMFRDA
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHCCCCCEEEEEEEHHHHHHH
FPNLVKFLDEVFEAVRELDEPEGWNFVRKHALDHRIFGDPPGAYGAGVNYAVHASAWDDR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCH
SDLADVYVRWGGYAYGSDVYGEEAFSEFRRALSTVRAVSVNQSSHEWDVLSCCCHFAFHG
HHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GMVAAAEHHSGERVECYHHDTTDPHRVITRPIEEELVRLVEQKLANDEWIEAMLEHGAKG
CEEEEHHCCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
VGEWLKRVENLFGWDATTGRVPSECYEKIEDVLERYGPRFSDENPYAVEYARERLLEAKK
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TGSVALADDVGRVLLHLRLDADVLVGLDDQRVDHGDDRPDRRRVLDRTEQQVVAAQRRRH
CCCEEEHHHHHHHHHHHEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YVGAPVGGLVG
CCCCCCCCCCC
>Mature Secondary Structure
MLPTPGVPRLELEEELRKHVPDEAKEFVRSVLSRLLACEREIDRTLEALDGCYVEPGPAG
CCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NPTRGDVDVLPTGKNFYSVDPRKVPTRRAWKVGKKLAENTIERYLEEHGRYPESVGIVLW
CCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ASDVMRTGGEVLSQVMWLLGVRPEWDESGIVSGFEVVPLEELERPRIDVVVRISGMFRDA
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHCCCCCEEEEEEEHHHHHHH
FPNLVKFLDEVFEAVRELDEPEGWNFVRKHALDHRIFGDPPGAYGAGVNYAVHASAWDDR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCH
SDLADVYVRWGGYAYGSDVYGEEAFSEFRRALSTVRAVSVNQSSHEWDVLSCCCHFAFHG
HHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GMVAAAEHHSGERVECYHHDTTDPHRVITRPIEEELVRLVEQKLANDEWIEAMLEHGAKG
CEEEEHHCCCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
VGEWLKRVENLFGWDATTGRVPSECYEKIEDVLERYGPRFSDENPYAVEYARERLLEAKK
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TGSVALADDVGRVLLHLRLDADVLVGLDDQRVDHGDDRPDRRRVLDRTEQQVVAAQRRRH
CCCEEEHHHHHHHHHHHEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YVGAPVGGLVG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Hydrogenobyrinic acid a,c diamide; Co2+

Specific reaction: ATP + hydrogenobyrinic acid a,c-diamide + Co2+ = ADP + phosphate + cob(II)yrinic acid a,c-diamide + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]