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The map label for this gene is 20093858

Identifier: 20093858

GI number: 20093858

Start: 395697

End: 395897

Strand: Direct

Name: 20093858

Synonym: MK0420

Alternate gene names: NA

Gene position: 395697-395897 (Clockwise)

Preceding gene: 20093857

Following gene: 20093859

Centisome position: 23.35

GC content: 57.21

Gene sequence:

>201_bases
GTGCCTAAACGACTACGCAGGTGTAAGGAGTGCGGGGAATACACGCTTCAAAGGGACAAATGTCCGCATTGCGGTGGAGA
TCTGGAGGTGCCGCACCCGCACCGATTCTCCCCGGAAGACCCGTACGGTAAATATCGAAGGAAGCTGAAGAAAAGGGTGT
GGGCCGAGAAATTCGGCCCGCCTTCCGGCGAGGGGGATTAA

Upstream 100 bases:

>100_bases
AGAGAAAATGGTCAGGAAGGCAGCTCAGGCCGCGATCGACCACGTGGAAGAGCACGGAGGCGAGGGCGAGTTCCACCGGG
AGATCGAGGAGGGGTAAAGC

Downstream 100 bases:

>100_bases
AAGTTGGACCTGCTGAAGCTGGCCCGCGGAAACACCGTGATCAAGTTCGATTTCGAGCCAGAAGTGGAGGAGCCGGTCCT
CGTGGAGGGGCTTCCCGGCA

Product: Zn-ribbon-containing RNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 66; Mature: 65

Protein sequence:

>66_residues
MPKRLRRCKECGEYTLQRDKCPHCGGDLEVPHPHRFSPEDPYGKYRRKLKKRVWAEKFGPPSGEGD

Sequences:

>Translated_66_residues
MPKRLRRCKECGEYTLQRDKCPHCGGDLEVPHPHRFSPEDPYGKYRRKLKKRVWAEKFGPPSGEGD
>Mature_65_residues
PKRLRRCKECGEYTLQRDKCPHCGGDLEVPHPHRFSPEDPYGKYRRKLKKRVWAEKFGPPSGEGD

Specific function: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA

COG id: COG2260

COG function: function code J; Predicted Zn-ribbon RNA-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NOP10 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NOP10_METKA (Q8TY85)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613705.1
- ProteinModelPortal:   Q8TY85
- SMR:   Q8TY85
- GeneID:   1477723
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0420
- NMPDR:   fig|190192.1.peg.418
- HOGENOM:   HBG498094
- BioCyc:   MKAN190192:MK0420-MONOMER
- HAMAP:   MF_00803
- InterPro:   IPR007264

Pfam domain/function: PF04135 Nop10p

EC number: NA

Molecular weight: Translated: 7755; Mature: 7624

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRLRRCKECGEYTLQRDKCPHCGGDLEVPHPHRFSPEDPYGKYRRKLKKRVWAEKFGP
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
PSGEGD
CCCCCC
>Mature Secondary Structure 
PKRLRRCKECGEYTLQRDKCPHCGGDLEVPHPHRFSPEDPYGKYRRKLKKRVWAEKFGP
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
PSGEGD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014