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The map label for this gene is IMP4

Identifier: 20093815

GI number: 20093815

Start: 364743

End: 365321

Strand: Reverse

Name: IMP4

Synonym: MK0377

Alternate gene names: NA

Gene position: 365321-364743 (Counterclockwise)

Preceding gene: 20093816

Following gene: 20093814

Centisome position: 21.55

GC content: 56.82

Gene sequence:

>579_bases
TTGAGACCGGCGGCCATCACCACCTCACAGCGTCCCGCTCGTCGCACGCGCTCGCTATGTCGTGACCTGGAGTGCGCACT
ACCCGATGCTACTTACGTTCTGAGGGGTACGAAGAACCTCCGGGACACCGTACTGGAAGCACTAGAATCTGGTGCTGAAG
TCCTGTTCTACGTGACGGAAGCCAAAGGCAACCCCGCCCGACTCCATGTAATAGATCTCGGAGAGATCCCACCCAGGTTA
CGATTATCATTCTGGCTAGGTGGTGTCAAGCTACAGCGTGAGCTCTTCGGGAATAGGGTTGATCTTTCAGGTGATCTGGT
GATCACGACGTCGAAACGCCCAGTTTCCGGTCACATGAAGGTCGCGGAGTCGCTGTCCGAAGTCCTCGGAGTAGAATTCG
TTCCCCGAGCGGGCTCCTTGGAGGATGTACTTGAGGAGGCCCTAGCCGACGTGCTGTTGGTGGTCGAAGGCCATCCTCGT
CACTTAGGGACCCTTACCTTCTACCGTCGCACCGAGAAGGTCGGACCGTCCCTGTTCTACCGGGATTTCCGCACCAAGGA
CGAGAGGATGAAGTTATAA

Upstream 100 bases:

>100_bases
TCAGGTTGGACATCAACGAAGACCCCATTCGCTGCACCCACTGTGGTTTCAGACTGGTGATGAAGCCCCGGCACCCCGTG
CCCAGGAGGTATAAAGCTCG

Downstream 100 bases:

>100_bases
CACGAGGGTGGGACCGTGCACGCGCTTCGATGTGAGGCCGAGCTCAAATCGGAACGAGTCGCCAGAGTGGTCTACGAATC
GGTGTTACCGGACGTTAAAC

Product: ribosomal biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRPAAITTSQRPARRTRSLCRDLECALPDATYVLRGTKNLRDTVLEALESGAEVLFYVTEAKGNPARLHVIDLGEIPPRL
RLSFWLGGVKLQRELFGNRVDLSGDLVITTSKRPVSGHMKVAESLSEVLGVEFVPRAGSLEDVLEEALADVLLVVEGHPR
HLGTLTFYRRTEKVGPSLFYRDFRTKDERMKL

Sequences:

>Translated_192_residues
MRPAAITTSQRPARRTRSLCRDLECALPDATYVLRGTKNLRDTVLEALESGAEVLFYVTEAKGNPARLHVIDLGEIPPRL
RLSFWLGGVKLQRELFGNRVDLSGDLVITTSKRPVSGHMKVAESLSEVLGVEFVPRAGSLEDVLEEALADVLLVVEGHPR
HLGTLTFYRRTEKVGPSLFYRDFRTKDERMKL
>Mature_192_residues
MRPAAITTSQRPARRTRSLCRDLECALPDATYVLRGTKNLRDTVLEALESGAEVLFYVTEAKGNPARLHVIDLGEIPPRL
RLSFWLGGVKLQRELFGNRVDLSGDLVITTSKRPVSGHMKVAESLSEVLGVEFVPRAGSLEDVLEEALADVLLVVEGHPR
HLGTLTFYRRTEKVGPSLFYRDFRTKDERMKL

Specific function: Probably involved in the biogenesis of the ribosome

COG id: COG2136

COG function: function code JA; Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Brix domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BRIX_METKA (Q8TYC5)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613662.1
- ProteinModelPortal:   Q8TYC5
- SMR:   Q8TYC5
- GeneID:   1477680
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0377
- NMPDR:   fig|190192.1.peg.375
- OMA:   IWIMEDG
- ProtClustDB:   PRK03972
- BioCyc:   MKAN190192:MK0377-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_00699
- InterPro:   IPR004154
- InterPro:   IPR007109
- SMART:   SM00879

Pfam domain/function: PF04427 Brix; SSF52954 Anticodon_bd

EC number: NA

Molecular weight: Translated: 21528; Mature: 21528

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50833 BRIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAAITTSQRPARRTRSLCRDLECALPDATYVLRGTKNLRDTVLEALESGAEVLFYVTE
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEE
AKGNPARLHVIDLGEIPPRLRLSFWLGGVKLQRELFGNRVDLSGDLVITTSKRPVSGHMK
CCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHCCCEECCCCCEEEEECCCCCCHHHH
VAESLSEVLGVEFVPRAGSLEDVLEEALADVLLVVEGHPRHLGTLTFYRRTEKVGPSLFY
HHHHHHHHHCCEECCCCCCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHHH
RDFRTKDERMKL
HHHCCCHHHCCC
>Mature Secondary Structure
MRPAAITTSQRPARRTRSLCRDLECALPDATYVLRGTKNLRDTVLEALESGAEVLFYVTE
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEE
AKGNPARLHVIDLGEIPPRLRLSFWLGGVKLQRELFGNRVDLSGDLVITTSKRPVSGHMK
CCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHCCCEECCCCCEEEEECCCCCCHHHH
VAESLSEVLGVEFVPRAGSLEDVLEEALADVLLVVEGHPRHLGTLTFYRRTEKVGPSLFY
HHHHHHHHHCCEECCCCCCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHHH
RDFRTKDERMKL
HHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014