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The map label for this gene is fdhA [H]

Identifier: 20093759

GI number: 20093759

Start: 311717

End: 313774

Strand: Direct

Name: fdhA [H]

Synonym: MK0321

Alternate gene names: 20093759

Gene position: 311717-313774 (Clockwise)

Preceding gene: 20093754

Following gene: 20093760

Centisome position: 18.39

GC content: 67.59

Gene sequence:

>2058_bases
GTGGCTAGGATGCGTTTCGTGCCGCAGGTGTGCCCGTTCTGTGGTTGCGGCTGTGGCATCCTGGTTGGAACCGATGGAGA
GGAGATCAAGCTGCTGGAACCGTGGAGGCGGCATCCAGTGAACGAGGGTAGACAGTGCGTCAAGCTCTGGGAGCTACCCG
AGGCCGTGCAGAAGGACCGTCTGGAGCGGCCGGTTCGGATGACCGAGTCGGGCGAGCCGCGCGAGCTCTCCTGGAACCGG
GCGCTCGAGGAGGTGGCCGAGGTCCTCTCGACCCATGAGCCTGAGGAGGTGTACTTCGTCACCTCGGCCAAGGCCACGAA
CGAGGACAACTACGTGGCGCAGAAGCTCGCACGGACCCTCGGCACGAACAACGTGGACCACTGCGCGCGCCTGTGACACG
CCCCTACGGTGGTCGCGCTGTCCGAGCTCCTGGGTTCCGGGGCGATGACTAACTCGATCCCGGACCTGGTCGAGGCGGAC
TGCTACCTGGTCGCGGGTTCGAACACGGCGGAGCAGCACCCGATCGTGTACCGCCGGATCCTCCAGGGTCTCGAGGAGAA
CGACGCGGATCTCATCGTCCTCGACCCGAGGCGCACGCAGATCGCGGAACTGGCGGATATACACCTACAGGTGAGGCCGC
GGACCGACCTGATCGTGTTCCTCTACATGGCCAAAGTGATCGTCGAGGAGGGACTGCACGACGGGACGTTCATCGAGGAG
CGGACCACGGGGTTCGAGTCGTTCGAGGAGTACGTGCGTGAGGCGGTCTCCGAGGGGGACGTCAGGAGGATCGCCGGCGT
GGACCCCGAGGACGTGCGCAAGGCCGCCGTGCGCTACGCCGAGGCGGAGCGCGGGTGCATCCTCTACTGCATGGGACTCA
CGCACCACGACATCGCCACCCGGACGGTCCGCGCGCTGTGCGCGCTCGCCCTCCTGACGGGCAACGTGGGCAGACCGGGC
ACCGGCGTCAACCCGCTCCGCGGGCAGAACAACGTCCAGGGAGCGTGCGACGTGGGCGCCCTGGCGACGCACTTCCCCGG
GTACCGGCCGATCAACACGGAAACAGCGAATGAAATGTCGAAAATTTGGAGTTTCGAGGTGCCGGACGAGCCCGGCCTCA
AGCTCACGGAGGCCTTCGACGCGGACGAGATCACCGTCATGTACGTAGTCGGCGAGAACCCCGCCGTCTCCGAGCCGAAC
ACACGTCACGCGGTTGAGAAGCTCGAAAGCCTCGAGTTCCTGGTGGTCCAGGACCTGTACCTGACCGAGACCGGCGAGCT
GGCGGACCTCGTGCTGCCGGCCGCCGGCTGGGCGGAGCGCACGGGCACGTTCACGGCCACCGATCGGCGCGTTCAGCTCG
CGGAGAAGGCCGTGGAGCCACCGGGCGAGGCCCGGCCCGACTGGTGGATCCTGGAGGCGGTGGCCCGACGACTGGGGCTC
AAGGGCTTCGGACACCGATCCCCGCGCGAGGTGTTCGAGGAGATCCGACGCGTCGTCCCGCAGTACCGAGGGATCACGTA
CGAACGACTCCGGAGACGCCCGGGCGGGATCCACTGGCCCTGTCCGAGCGAGGACCACCCGGGCACCCCGATCCTGCACA
CCGAGGAGTTCGCCACCGAGGACGGGAAGGCCCGGTTCCCGAAGCCCGAGGACGTGGAGTACCGGGAACCGGAGCGAGAC
GTGGACGAGGAGTACCCGCTGATCCTCACCACGGGCCGCGTGTACGCGCACTACCACACCCGCACAATCACGCGACGCTC
GCGGCTCCTGAGCGAGGAGGTGCCGGAGTCGTTCGTCGAGATCCACCCGAAGGACGCGGAGCGGTACGGCGTGCGAGACG
GGGAACTGGTGGTCGTCGAAACACCCTACGGCGAGTGGCGGTGCCGCGCTCGAGTCACCGATCGGGTGCGAGAGGGCACG
ATCTTCACGCCGTTCCACTTCGGCGAGAACGTCCTGACGCCCCACGACGTTCGCGATCCGGAGTCCGGGATCCCGGAGTA
CAAGTACGTCCCCGCCCGCGTCCGACCCGACTCCCGGGGGTCGGCCTCGAGGGGGTAG

Upstream 100 bases:

>100_bases
CGTCGACCCGAAGGGCCCCCACGCGGGGGTCCGGGGGAACCGCGGCCGAAACCCGGTCCCCACCCCTCTTCCTCCCCGGA
ACCTCAGGGGGTGAGAACCC

Downstream 100 bases:

>100_bases
ACACCGTGTCGAGCGTCGAGGTTCAGGTCGGCGGGTGCTACCTCGCCCGGTCCTCGGACCCCGACACCGTCAAGGAGGCC
GCGTGCGGGGGCGTCGTCAC

Product: selenocysteine-containing anaerobic dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 684

Protein sequence:

>685_residues
MARMRFVPQVCPFCGCGCGILVGTDGEEIKLLEPWRRHPVNEGRQCVKLWELPEAVQKDRLERPVRMTESGEPRELSWNR
ALEEVAEVLSTHEPEEVYFVTSAKATNEDNYVAQKLARTLGTNNVDHCARLUHAPTVVALSELLGSGAMTNSIPDLVEAD
CYLVAGSNTAEQHPIVYRRILQGLEENDADLIVLDPRRTQIAELADIHLQVRPRTDLIVFLYMAKVIVEEGLHDGTFIEE
RTTGFESFEEYVREAVSEGDVRRIAGVDPEDVRKAAVRYAEAERGCILYCMGLTHHDIATRTVRALCALALLTGNVGRPG
TGVNPLRGQNNVQGACDVGALATHFPGYRPINTETANEMSKIWSFEVPDEPGLKLTEAFDADEITVMYVVGENPAVSEPN
TRHAVEKLESLEFLVVQDLYLTETGELADLVLPAAGWAERTGTFTATDRRVQLAEKAVEPPGEARPDWWILEAVARRLGL
KGFGHRSPREVFEEIRRVVPQYRGITYERLRRRPGGIHWPCPSEDHPGTPILHTEEFATEDGKARFPKPEDVEYREPERD
VDEEYPLILTTGRVYAHYHTRTITRRSRLLSEEVPESFVEIHPKDAERYGVRDGELVVVETPYGEWRCRARVTDRVREGT
IFTPFHFGENVLTPHDVRDPESGIPEYKYVPARVRPDSRGSASRG

Sequences:

>Translated_685_residues
MARMRFVPQVCPFCGCGCGILVGTDGEEIKLLEPWRRHPVNEGRQCVKLWELPEAVQKDRLERPVRMTESGEPRELSWNR
ALEEVAEVLSTHEPEEVYFVTSAKATNEDNYVAQKLARTLGTNNVDHCARL*HAPTVVALSELLGSGAMTNSIPDLVEAD
CYLVAGSNTAEQHPIVYRRILQGLEENDADLIVLDPRRTQIAELADIHLQVRPRTDLIVFLYMAKVIVEEGLHDGTFIEE
RTTGFESFEEYVREAVSEGDVRRIAGVDPEDVRKAAVRYAEAERGCILYCMGLTHHDIATRTVRALCALALLTGNVGRPG
TGVNPLRGQNNVQGACDVGALATHFPGYRPINTETANEMSKIWSFEVPDEPGLKLTEAFDADEITVMYVVGENPAVSEPN
TRHAVEKLESLEFLVVQDLYLTETGELADLVLPAAGWAERTGTFTATDRRVQLAEKAVEPPGEARPDWWILEAVARRLGL
KGFGHRSPREVFEEIRRVVPQYRGITYERLRRRPGGIHWPCPSEDHPGTPILHTEEFATEDGKARFPKPEDVEYREPERD
VDEEYPLILTTGRVYAHYHTRTITRRSRLLSEEVPESFVEIHPKDAERYGVRDGELVVVETPYGEWRCRARVTDRVREGT
IFTPFHFGENVLTPHDVRDPESGIPEYKYVPARVRPDSRGSASRG
>Mature_684_residues
ARMRFVPQVCPFCGCGCGILVGTDGEEIKLLEPWRRHPVNEGRQCVKLWELPEAVQKDRLERPVRMTESGEPRELSWNRA
LEEVAEVLSTHEPEEVYFVTSAKATNEDNYVAQKLARTLGTNNVDHCARL*HAPTVVALSELLGSGAMTNSIPDLVEADC
YLVAGSNTAEQHPIVYRRILQGLEENDADLIVLDPRRTQIAELADIHLQVRPRTDLIVFLYMAKVIVEEGLHDGTFIEER
TTGFESFEEYVREAVSEGDVRRIAGVDPEDVRKAAVRYAEAERGCILYCMGLTHHDIATRTVRALCALALLTGNVGRPGT
GVNPLRGQNNVQGACDVGALATHFPGYRPINTETANEMSKIWSFEVPDEPGLKLTEAFDADEITVMYVVGENPAVSEPNT
RHAVEKLESLEFLVVQDLYLTETGELADLVLPAAGWAERTGTFTATDRRVQLAEKAVEPPGEARPDWWILEAVARRLGLK
GFGHRSPREVFEEIRRVVPQYRGITYERLRRRPGGIHWPCPSEDHPGTPILHTEEFATEDGKARFPKPEDVEYREPERDV
DEEYPLILTTGRVYAHYHTRTITRRSRLLSEEVPESFVEIHPKDAERYGVRDGELVVVETPYGEWRCRARVTDRVREGTI
FTPFHFGENVLTPHDVRDPESGIPEYKYVPARVRPDSRGSASRG

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=699, Percent_Identity=36.623748211731, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI3868719, Length=621, Percent_Identity=27.6972624798712, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI3868720, Length=623, Percent_Identity=27.6083467094703, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788534, Length=565, Percent_Identity=27.6106194690265, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787778, Length=693, Percent_Identity=25.3968253968254, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI171474008, Length=670, Percent_Identity=22.8358208955224, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787231, Length=672, Percent_Identity=22.9166666666667, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081994, Length=535, Percent_Identity=23.3644859813084, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787870, Length=741, Percent_Identity=22.2672064777328, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI145693196, Length=522, Percent_Identity=21.264367816092, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565758, Length=153, Percent_Identity=30.0653594771242, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 77036; Mature: 76904

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMRFVPQVCPFCGCGCGILVGTDGEEIKLLEPWRRHPVNEGRQCVKLWELPEAVQKDR
CCCCCCCHHHHHHHCCCCEEEECCCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHH
LERPVRMTESGEPRELSWNRALEEVAEVLSTHEPEEVYFVTSAKATNEDNYVAQKLARTL
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
GTNNVDHCARLHAPTVVALSELLGSGAMTNSIPDLVEADCYLVAGSNTAEQHPIVYRRIL
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCCCHHHHHHH
QGLEENDADLIVLDPRRTQIAELADIHLQVRPRTDLIVFLYMAKVIVEEGLHDGTFIEER
HHCCCCCCCEEEECCCHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHH
TTGFESFEEYVREAVSEGDVRRIAGVDPEDVRKAAVRYAEAERGCILYCMGLTHHDIATR
HCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
TVRALCALALLTGNVGRPGTGVNPLRGQNNVQGACDVGALATHFPGYRPINTETANEMSK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
IWSFEVPDEPGLKLTEAFDADEITVMYVVGENPAVSEPNTRHAVEKLESLEFLVVQDLYL
HEECCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEEHHHC
TETGELADLVLPAAGWAERTGTFTATDRRVQLAEKAVEPPGEARPDWWILEAVARRLGLK
CCCCCHHHHHCCCCCCHHCCCCEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
GFGHRSPREVFEEIRRVVPQYRGITYERLRRRPGGIHWPCPSEDHPGTPILHTEEFATED
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECHHHCCCC
GKARFPKPEDVEYREPERDVDEEYPLILTTGRVYAHYHTRTITRRSRLLSEEVPESFVEI
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
HPKDAERYGVRDGELVVVETPYGEWRCRARVTDRVREGTIFTPFHFGENVLTPHDVRDPE
CCCCHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
SGIPEYKYVPARVRPDSRGSASRG
CCCCCCEEECCEECCCCCCCCCCC
>Mature Secondary Structure 
ARMRFVPQVCPFCGCGCGILVGTDGEEIKLLEPWRRHPVNEGRQCVKLWELPEAVQKDR
CCCCCCHHHHHHHCCCCEEEECCCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHH
LERPVRMTESGEPRELSWNRALEEVAEVLSTHEPEEVYFVTSAKATNEDNYVAQKLARTL
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
GTNNVDHCARLHAPTVVALSELLGSGAMTNSIPDLVEADCYLVAGSNTAEQHPIVYRRIL
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCCCHHHHHHH
QGLEENDADLIVLDPRRTQIAELADIHLQVRPRTDLIVFLYMAKVIVEEGLHDGTFIEER
HHCCCCCCCEEEECCCHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHH
TTGFESFEEYVREAVSEGDVRRIAGVDPEDVRKAAVRYAEAERGCILYCMGLTHHDIATR
HCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
TVRALCALALLTGNVGRPGTGVNPLRGQNNVQGACDVGALATHFPGYRPINTETANEMSK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
IWSFEVPDEPGLKLTEAFDADEITVMYVVGENPAVSEPNTRHAVEKLESLEFLVVQDLYL
HEECCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEEHHHC
TETGELADLVLPAAGWAERTGTFTATDRRVQLAEKAVEPPGEARPDWWILEAVARRLGLK
CCCCCHHHHHCCCCCCHHCCCCEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
GFGHRSPREVFEEIRRVVPQYRGITYERLRRRPGGIHWPCPSEDHPGTPILHTEEFATED
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECHHHCCCC
GKARFPKPEDVEYREPERDVDEEYPLILTTGRVYAHYHTRTITRRSRLLSEEVPESFVEI
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
HPKDAERYGVRDGELVVVETPYGEWRCRARVTDRVREGTIFTPFHFGENVLTPHDVRDPE
CCCCHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
SGIPEYKYVPARVRPDSRGSASRG
CCCCCCEEECCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]