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The map label for this gene is CysH

Identifier: 20093685

GI number: 20093685

Start: 234728

End: 235990

Strand: Direct

Name: CysH

Synonym: MK0245

Alternate gene names: NA

Gene position: 234728-235990 (Clockwise)

Preceding gene: 20093682

Following gene: 20093691

Centisome position: 13.85

GC content: 62.07

Gene sequence:

>1263_bases
GTGCACCTGCACGTGCTGGTGAGAGCCCGAAAGGACGCGTCGGCCGTGGAATCGGCGCTGGAGCGGTATTACCCGGACTG
GGAGTGGAAAGTGGAAACGCTCGGAGGTGAGCGCGATCCGTCGTGGATCGTCGGTTTGGCGCGTGAACGGTTCGAGGGTT
CCGACGCACTGTGGAAGGTACTTCTTCTGGGCCGGCGTAGTTACCCCGGTCGCGGGCGCGTGGTCTGGATGGAGGGATGG
TCGGCGGTGAACGTGGGCAAGGCGGAGGTCCGGAACGCCAGGCTGACCGAGATCGTGGACGGTATCGAGCTAGGACGTGC
CGCCCCGCGCCTGAGCGTGGCTTTCAGACGGGTACCGGAGCTCCGGCGAGGGAGGTTACTGACCGAGAACCAGGACGCGG
ATACCATGCTCCGGTGGGGTAAATTCACCGAGACAATCGCCGAGCTGGCTGGGGAGGAGCTACCTCCCGGTGCGTACTTC
TCACTCCGAAAGCCGGGGAACCCGCCGGAAGAAGTACTCTACGACGCCTCCGGTAAGCCGATCCTCAGGATCATCACGCC
GGACGAAGGCGAACCGAGCGTAAGCGTGCTCGGAGACGGGGAACCCTTCGATTCTAGGGCGTTCGTCCGTGAGAACCGTG
AGACGCTGGAGAACCTGTTCGAGGACGCCGTGGATTTTCTTGGAGGAGTGGCGGAGGAGTTCGATGTCCTGTTCGTGCCG
GTCAGCGGAGGGAAGGACAGCACGTGCTGCTTAGCGATAGCCGTCGAGACGACCGATCGCTTAGGGATCGACGTCGAAGC
CGTGTACGTGGATACTGGATACGACCTGGGCAGAGACGTCGTCGAAGACGTCGGAGCGGCGTTGGGAGTCGATATCAAGC
ACGTAGACGTTTCCGATGCGTTTGAACGTGGGTTGAGGGAGCGGAAGCCCACCCATGAGAACCGATGGTGCACCGGTGTG
AAGCTTTCCGGGATCAAGAAAGTGCTGAAGGATTTGGAGGGAGATGTCCTGCTGGTCGTGGGAGATCGAGACGCGGAGAG
CCGCAGGAGGAGATTGAGGCCGCCGGTCCACAGGAACCGGCTGCTCGACGTACCCGAAGTTAACCCTGTGAAAGGATGGG
GAGGGGCCGAGGTGCTCGGGACGTTGTTCCGATTGGGCCTACCGGTGAGCGAACTGTACGAGATCGGGTTCTATAGGTTG
GGTTGCTCCGTGTGCCCTTCCCTCACGGCGTGGGAGAGAGCGCTCATGGAGCTCAGCCGATGA

Upstream 100 bases:

>100_bases
TTCACCCTCCCATTCGAGCTCCCACCGAGCCTCCATCGATCTCACACCCATAACCGGTCGGAAGGGACGTCCCTCGGGGG
GTTAAAAGTTGGAAGGTAGG

Downstream 100 bases:

>100_bases
TCCTAACTGTTGGCTTCATCGCAACTCTCAAGCGCGTCGGAACCGCAGTTTCCTACGGACTCGACGGCGCGCCCGCGGGA
ACAACGTTACGGTTATTTTA

Product: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MHLHVLVRARKDASAVESALERYYPDWEWKVETLGGERDPSWIVGLARERFEGSDALWKVLLLGRRSYPGRGRVVWMEGW
SAVNVGKAEVRNARLTEIVDGIELGRAAPRLSVAFRRVPELRRGRLLTENQDADTMLRWGKFTETIAELAGEELPPGAYF
SLRKPGNPPEEVLYDASGKPILRIITPDEGEPSVSVLGDGEPFDSRAFVRENRETLENLFEDAVDFLGGVAEEFDVLFVP
VSGGKDSTCCLAIAVETTDRLGIDVEAVYVDTGYDLGRDVVEDVGAALGVDIKHVDVSDAFERGLRERKPTHENRWCTGV
KLSGIKKVLKDLEGDVLLVVGDRDAESRRRRLRPPVHRNRLLDVPEVNPVKGWGGAEVLGTLFRLGLPVSELYEIGFYRL
GCSVCPSLTAWERALMELSR

Sequences:

>Translated_420_residues
MHLHVLVRARKDASAVESALERYYPDWEWKVETLGGERDPSWIVGLARERFEGSDALWKVLLLGRRSYPGRGRVVWMEGW
SAVNVGKAEVRNARLTEIVDGIELGRAAPRLSVAFRRVPELRRGRLLTENQDADTMLRWGKFTETIAELAGEELPPGAYF
SLRKPGNPPEEVLYDASGKPILRIITPDEGEPSVSVLGDGEPFDSRAFVRENRETLENLFEDAVDFLGGVAEEFDVLFVP
VSGGKDSTCCLAIAVETTDRLGIDVEAVYVDTGYDLGRDVVEDVGAALGVDIKHVDVSDAFERGLRERKPTHENRWCTGV
KLSGIKKVLKDLEGDVLLVVGDRDAESRRRRLRPPVHRNRLLDVPEVNPVKGWGGAEVLGTLFRLGLPVSELYEIGFYRL
GCSVCPSLTAWERALMELSR
>Mature_420_residues
MHLHVLVRARKDASAVESALERYYPDWEWKVETLGGERDPSWIVGLARERFEGSDALWKVLLLGRRSYPGRGRVVWMEGW
SAVNVGKAEVRNARLTEIVDGIELGRAAPRLSVAFRRVPELRRGRLLTENQDADTMLRWGKFTETIAELAGEELPPGAYF
SLRKPGNPPEEVLYDASGKPILRIITPDEGEPSVSVLGDGEPFDSRAFVRENRETLENLFEDAVDFLGGVAEEFDVLFVP
VSGGKDSTCCLAIAVETTDRLGIDVEAVYVDTGYDLGRDVVEDVGAALGVDIKHVDVSDAFERGLRERKPTHENRWCTGV
KLSGIKKVLKDLEGDVLLVVGDRDAESRRRRLRPPVHRNRLLDVPEVNPVKGWGGAEVLGTLFRLGLPVSELYEIGFYRL
GCSVCPSLTAWERALMELSR

Specific function: Unknown

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PUA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002500
- InterPro:   IPR002478
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR004521 [H]

Pfam domain/function: PF01507 PAPS_reduct; PF01472 PUA [H]

EC number: NA

Molecular weight: Translated: 46848; Mature: 46848

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLHVLVRARKDASAVESALERYYPDWEWKVETLGGERDPSWIVGLARERFEGSDALWKV
CEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHH
LLLGRRSYPGRGRVVWMEGWSAVNVGKAEVRNARLTEIVDGIELGRAAPRLSVAFRRVPE
HHHHCCCCCCCCEEEEEECCCEECCCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCHH
LRRGRLLTENQDADTMLRWGKFTETIAELAGEELPPGAYFSLRKPGNPPEEVLYDASGKP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHEECCCCCC
ILRIITPDEGEPSVSVLGDGEPFDSRAFVRENRETLENLFEDAVDFLGGVAEEFDVLFVP
EEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VSGGKDSTCCLAIAVETTDRLGIDVEAVYVDTGYDLGRDVVEDVGAALGVDIKHVDVSDA
CCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECCHHHH
FERGLRERKPTHENRWCTGVKLSGIKKVLKDLEGDVLLVVGDRDAESRRRRLRPPVHRNR
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCHHHCC
LLDVPEVNPVKGWGGAEVLGTLFRLGLPVSELYEIGFYRLGCSVCPSLTAWERALMELSR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHLHVLVRARKDASAVESALERYYPDWEWKVETLGGERDPSWIVGLARERFEGSDALWKV
CEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHH
LLLGRRSYPGRGRVVWMEGWSAVNVGKAEVRNARLTEIVDGIELGRAAPRLSVAFRRVPE
HHHHCCCCCCCCEEEEEECCCEECCCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCHH
LRRGRLLTENQDADTMLRWGKFTETIAELAGEELPPGAYFSLRKPGNPPEEVLYDASGKP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHEECCCCCC
ILRIITPDEGEPSVSVLGDGEPFDSRAFVRENRETLENLFEDAVDFLGGVAEEFDVLFVP
EEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VSGGKDSTCCLAIAVETTDRLGIDVEAVYVDTGYDLGRDVVEDVGAALGVDIKHVDVSDA
CCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECCHHHH
FERGLRERKPTHENRWCTGVKLSGIKKVLKDLEGDVLLVVGDRDAESRRRRLRPPVHRNR
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCHHHCC
LLDVPEVNPVKGWGGAEVLGTLFRLGLPVSELYEIGFYRLGCSVCPSLTAWERALMELSR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]