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The map label for this gene is nadX

Identifier: 20093534

GI number: 20093534

Start: 87467

End: 88255

Strand: Reverse

Name: nadX

Synonym: MK0094

Alternate gene names: 20093534

Gene position: 88255-87467 (Counterclockwise)

Preceding gene: 20093535

Following gene: 20093533

Centisome position: 5.21

GC content: 61.85

Gene sequence:

>789_bases
ATGAAGAAGCTGAGTTTAGCGCTCGTAGGCGCTGGAGGCATCGGAACGACGGTGTTGAGGGAGATCCGTGAAGGACGGCT
CGAAGGTAAGGTGGAACCGGTTCTGGTCTGTGATCGTCACCCGGAGAAGCTCAAACGCATCGAGCGGTGGTTCCCCGACT
GCGATACCTCTACCGACCTAGATGACGCCATGAGCGCCGAAGCCGACGTGCTGCTCGAGGCCGCCTCCGTGGAAGCGGCG
GCTAGCCTCTTACCTGACGCGCTGAAGAGGTTCGATGTGATCGTGATGAGCGTGGGAGCGCTGGTGCTTGAGGAGGGCCT
GCTGAGTCGATGTCGCGAGGTCGCGGAAGTCACCGGACATCGCCTTCACGTTCCGTCCGGTGCGGTAGGAGGTCTAGACG
TGCTGCGAGCGCTGCGAGGTCGGGTGAGAGAGGTCACTCTCACCACCATCAAGCCTCCGAAAGCCCTGAACAAGGACGTT
TCCGAGCGGACAGTACTCTACGAAGGTTCCGTGCGGGATGCCGTCCGCAAGTTCCCCAAGAACATCAACGTGGCGGCCGC
CGTGTCGCTGGCCGTAGGCGACCCCTCACTGGTCACAGTTCGGATCGTCTGCGACCCCGAGGTCTCAGTCAACACGCACG
TCATCGAGGTTGAGTCGAGCGCAGGTACGTACCGGTTCGAGCTGAGGAACGAAGCGCTCCCGGATAACCCAAAGACGAGC
GCCGTCGCCGCGTACTCCGCCGTGGCTTTGATCGAGCGGATGACCGAGGGGATTCGAGTGGGCACTTGA

Upstream 100 bases:

>100_bases
CCGGGTCATACGGTGCGATTGGATTGCGACTACCCCTCCGAGGGAAAGCCGATGCTTCCGGAGGGTCTGGTCGAGTACCT
GAAGGAGGGTATCGTCGACT

Downstream 100 bases:

>100_bases
AGCCCGTGGAACCCTGTGATCTCGAGGTATACGCGGACCTTAGGGTACCCCCCAACACACACCTGGTTCTGCGGATCGAC
GGAAGGGCGTTCACCAAACT

Product: dinucleotide-utilizing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKKLSLALVGAGGIGTTVLREIREGRLEGKVEPVLVCDRHPEKLKRIERWFPDCDTSTDLDDAMSAEADVLLEAASVEAA
ASLLPDALKRFDVIVMSVGALVLEEGLLSRCREVAEVTGHRLHVPSGAVGGLDVLRALRGRVREVTLTTIKPPKALNKDV
SERTVLYEGSVRDAVRKFPKNINVAAAVSLAVGDPSLVTVRIVCDPEVSVNTHVIEVESSAGTYRFELRNEALPDNPKTS
AVAAYSAVALIERMTEGIRVGT

Sequences:

>Translated_262_residues
MKKLSLALVGAGGIGTTVLREIREGRLEGKVEPVLVCDRHPEKLKRIERWFPDCDTSTDLDDAMSAEADVLLEAASVEAA
ASLLPDALKRFDVIVMSVGALVLEEGLLSRCREVAEVTGHRLHVPSGAVGGLDVLRALRGRVREVTLTTIKPPKALNKDV
SERTVLYEGSVRDAVRKFPKNINVAAAVSLAVGDPSLVTVRIVCDPEVSVNTHVIEVESSAGTYRFELRNEALPDNPKTS
AVAAYSAVALIERMTEGIRVGT
>Mature_262_residues
MKKLSLALVGAGGIGTTVLREIREGRLEGKVEPVLVCDRHPEKLKRIERWFPDCDTSTDLDDAMSAEADVLLEAASVEAA
ASLLPDALKRFDVIVMSVGALVLEEGLLSRCREVAEVTGHRLHVPSGAVGGLDVLRALRGRVREVTLTTIKPPKALNKDV
SERTVLYEGSVRDAVRKFPKNINVAAAVSLAVGDPSLVTVRIVCDPEVSVNTHVIEVESSAGTYRFELRNEALPDNPKTS
AVAAYSAVALIERMTEGIRVGT

Specific function: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate

COG id: COG1712

COG function: function code R; Predicted dinucleotide-utilizing enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-aspartate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPD_METKA (Q8TZ45)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613381.1
- ProteinModelPortal:   Q8TZ45
- SMR:   Q8TZ45
- GeneID:   1477397
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0094
- NMPDR:   fig|190192.1.peg.94
- HOGENOM:   HBG649642
- OMA:   LATIRRH
- BioCyc:   MKAN190192:MK0094-MONOMER
- BRENDA:   1.4.1.21
- HAMAP:   MF_01265
- InterPro:   IPR005106
- InterPro:   IPR002811
- InterPro:   IPR011182
- InterPro:   IPR020626
- InterPro:   IPR022487
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF005227
- TIGRFAMs:   TIGR03855

Pfam domain/function: PF01958 DUF108; PF03447 NAD_binding_3

EC number: =1.4.1.21

Molecular weight: Translated: 28186; Mature: 28186

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: ACT_SITE 213-213 BINDING 128-128 BINDING 183-183

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSLALVGAGGIGTTVLREIREGRLEGKVEPVLVCDRHPEKLKRIERWFPDCDTSTDL
CCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCC
DDAMSAEADVLLEAASVEAAASLLPDALKRFDVIVMSVGALVLEEGLLSRCREVAEVTGH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLHVPSGAVGGLDVLRALRGRVREVTLTTIKPPKALNKDVSERTVLYEGSVRDAVRKFPK
EEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHCCCCHHCEEEEECCHHHHHHHCCC
NINVAAAVSLAVGDPSLVTVRIVCDPEVSVNTHVIEVESSAGTYRFELRNEALPDNPKTS
CCCEEEEEEEEECCCCEEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCHH
AVAAYSAVALIERMTEGIRVGT
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKLSLALVGAGGIGTTVLREIREGRLEGKVEPVLVCDRHPEKLKRIERWFPDCDTSTDL
CCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCC
DDAMSAEADVLLEAASVEAAASLLPDALKRFDVIVMSVGALVLEEGLLSRCREVAEVTGH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLHVPSGAVGGLDVLRALRGRVREVTLTTIKPPKALNKDVSERTVLYEGSVRDAVRKFPK
EEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHCCCCHHCEEEEECCHHHHHHHCCC
NINVAAAVSLAVGDPSLVTVRIVCDPEVSVNTHVIEVESSAGTYRFELRNEALPDNPKTS
CCCEEEEEEEEECCCCEEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCHH
AVAAYSAVALIERMTEGIRVGT
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014