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The map label for this gene is RPB11

Identifier: 20093498

GI number: 20093498

Start: 56430

End: 56768

Strand: Reverse

Name: RPB11

Synonym: MK0058

Alternate gene names: 20093498

Gene position: 56768-56430 (Counterclockwise)

Preceding gene: 20093499

Following gene: 20093497

Centisome position: 3.35

GC content: 53.69

Gene sequence:

>339_bases
GTGAAACTGCCCGAGGTTGAAGTTGTCGTTAAGAAATACGATAAAGATGAGGTCCTACTCGAGCTGCCCGGTGAGGACCA
CACGTTATGTAATCTCTTAAGGTGGGCCTTAAACCGGCAGGACGGAATCATCGCAACTTACAGGATTGAGCACCCTATAC
TCGGTAAAGAACACAAAGTCGACGAAGAACGGTACGTACCGCCGAAGATGCGTATACGGGCTGTCGATGAGGACGCCGAC
GCCAGAGAAGCCCTCGAGCGGGCCATAGAGGAACTGCTGGAGCTGGTGGAAGAAGCGAAGGAGGAGTTCTCGGGGGCGCT
GGAGGAGAAGGAAAGTTGA

Upstream 100 bases:

>100_bases
ATTAGAGGAGATAGCGTCCGAGCTCCGGAAAGCCCGTAAAGGTAGGGGTAAAACCCTGGAGGACTTCCTCCATGAACCCT
TGTGACGGGGTGAAGGTGCC

Downstream 100 bases:

>100_bases
AGCTCAGAGAGGTGAAGCCCGAGATCAGGGTGTTGGGAATCGACGACGGCTACTACGGTCCCGAGGACGATAGGGCACTC
GTTGTCGGTGTCGTGATGCG

Product: DNA-directed RNA polymerase, subunit L

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MKLPEVEVVVKKYDKDEVLLELPGEDHTLCNLLRWALNRQDGIIATYRIEHPILGKEHKVDEERYVPPKMRIRAVDEDAD
AREALERAIEELLELVEEAKEEFSGALEEKES

Sequences:

>Translated_112_residues
MKLPEVEVVVKKYDKDEVLLELPGEDHTLCNLLRWALNRQDGIIATYRIEHPILGKEHKVDEERYVPPKMRIRAVDEDAD
AREALERAIEELLELVEEAKEEFSGALEEKES
>Mature_112_residues
MKLPEVEVVVKKYDKDEVLLELPGEDHTLCNLLRWALNRQDGIIATYRIEHPILGKEHKVDEERYVPPKMRIRAVDEDAD
AREALERAIEELLELVEEAKEEFSGALEEKES

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG1761

COG function: function code K; DNA-directed RNA polymerase, subunit L

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOL_METKA (Q8TZ81)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613345.1
- ProteinModelPortal:   Q8TZ81
- SMR:   Q8TZ81
- GeneID:   1477361
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0058
- NMPDR:   fig|190192.1.peg.58
- BioCyc:   MKAN190192:MK0058-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_00261
- InterPro:   IPR009025
- InterPro:   IPR008193
- InterPro:   IPR022905

Pfam domain/function: SSF55257 RNAP_RBP11-like

EC number: =2.7.7.6

Molecular weight: Translated: 13024; Mature: 13024

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS01154 RNA_POL_L_13KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPEVEVVVKKYDKDEVLLELPGEDHTLCNLLRWALNRQDGIIATYRIEHPILGKEHKV
CCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
DEERYVPPKMRIRAVDEDADAREALERAIEELLELVEEAKEEFSGALEEKES
CHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLPEVEVVVKKYDKDEVLLELPGEDHTLCNLLRWALNRQDGIIATYRIEHPILGKEHKV
CCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
DEERYVPPKMRIRAVDEDADAREALERAIEELLELVEEAKEEFSGALEEKES
CHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014