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The map label for this gene is 20093495

Identifier: 20093495

GI number: 20093495

Start: 53735

End: 54652

Strand: Reverse

Name: 20093495

Synonym: MK0055

Alternate gene names: NA

Gene position: 54652-53735 (Counterclockwise)

Preceding gene: 20093496

Following gene: 20093491

Centisome position: 3.22

GC content: 58.39

Gene sequence:

>918_bases
TTGCTACACGCGGACGTATTGAAGGTCCTCCGTAAGCAGGGTTATGGTCTAGTCGGGAAGCATTCCGCGGTCAAGCCGTG
TCACTGGTGCCGGGAAGCGATTAAGAACGGTAGGCACTGCTACAAGGCGAAATTCTACGGGGTGGAGAGTCATCGGTGCC
TTCAGATGACTCCTACGGTAGCTTGGTGTCAGCAGCGCTGCGTGTACTGCTGGAGACCGGTCGAACTCACCGTAGGAACT
CACGATGTACCCGATCCGGACGATCCCGACCTGATCGTAGAGGAGAGCGTAGAGCAACAGCGACGCTTCCTCCAAGGGTA
CGGGCACCTCGAAGGTGAAGCTCGTAAACGCTGGAAAGAATCCCTCGAGCCCAGACACGCCGCGATCAGTCTCGCAGGTG
AACCCACCCTGTACCCAAGAATCGGCGAACTGATCGACGCTTTTCATTCCCATGGGTTTGACACTACGTTCCTGGTAACC
AACGGGCTGCGACCCGACCGAGTGGAGGAACTGGAACGTGAGCCGACACAGCTGTACGTGTCCTTGGATTCACCGAACGA
GGAGCTACATCGTCAGATCAATAGACCTACGATTCCGGACTCCTGGGACCGGATCATGAGGACGTTGGAGTTACTGAATT
CCCTCTCCTGCCGGACGGTGATCCGCATCACTGCGATTAAAGGCTGGAACATGGAGGGGACCGCCGAGGAGTTCGGTGAA
CTGCTGGCCGACGTCGAGCCGGACTATGTCGAAGTGAAGGCGTTCATGTGCGTGGGATGGGCGGCCTTCCGGATGTCGCC
GGACAACATGCCCTCGCACGAAGAGGTACGGAAGTTCGCGGCGGAGATCGCGGAGCACGCGGGATTCGAGCTAGTCGACG
AGTCACCACCCAGCCGAGTGGCGCTTCTGAGCTCCTAG

Upstream 100 bases:

>100_bases
GCCGTGGTAACTTCCCGAGTGAATGCGACCGACCTCATGATGACTACTGTTAAGCCGGGAATTTTTTCGGACGGGAAAGG
CCGTTCGGGGGTGATCTAGG

Downstream 100 bases:

>100_bases
CTGAGCTCCCGGCCTCCCGCATGCGACAATCGTTATTGAACCAGTAACGATTACGGCGGAGGGGGAAGAAATCGATCACT
CCTCGGTGGACAGTGCGTCG

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLHADVLKVLRKQGYGLVGKHSAVKPCHWCREAIKNGRHCYKAKFYGVESHRCLQMTPTVAWCQQRCVYCWRPVELTVGT
HDVPDPDDPDLIVEESVEQQRRFLQGYGHLEGEARKRWKESLEPRHAAISLAGEPTLYPRIGELIDAFHSHGFDTTFLVT
NGLRPDRVEELEREPTQLYVSLDSPNEELHRQINRPTIPDSWDRIMRTLELLNSLSCRTVIRITAIKGWNMEGTAEEFGE
LLADVEPDYVEVKAFMCVGWAAFRMSPDNMPSHEEVRKFAAEIAEHAGFELVDESPPSRVALLSS

Sequences:

>Translated_305_residues
MLHADVLKVLRKQGYGLVGKHSAVKPCHWCREAIKNGRHCYKAKFYGVESHRCLQMTPTVAWCQQRCVYCWRPVELTVGT
HDVPDPDDPDLIVEESVEQQRRFLQGYGHLEGEARKRWKESLEPRHAAISLAGEPTLYPRIGELIDAFHSHGFDTTFLVT
NGLRPDRVEELEREPTQLYVSLDSPNEELHRQINRPTIPDSWDRIMRTLELLNSLSCRTVIRITAIKGWNMEGTAEEFGE
LLADVEPDYVEVKAFMCVGWAAFRMSPDNMPSHEEVRKFAAEIAEHAGFELVDESPPSRVALLSS
>Mature_305_residues
MLHADVLKVLRKQGYGLVGKHSAVKPCHWCREAIKNGRHCYKAKFYGVESHRCLQMTPTVAWCQQRCVYCWRPVELTVGT
HDVPDPDDPDLIVEESVEQQRRFLQGYGHLEGEARKRWKESLEPRHAAISLAGEPTLYPRIGELIDAFHSHGFDTTFLVT
NGLRPDRVEELEREPTQLYVSLDSPNEELHRQINRPTIPDSWDRIMRTLELLNSLSCRTVIRITAIKGWNMEGTAEEFGE
LLADVEPDYVEVKAFMCVGWAAFRMSPDNMPSHEEVRKFAAEIAEHAGFELVDESPPSRVALLSS

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=286, Percent_Identity=35.6643356643357, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI224282123, Length=238, Percent_Identity=33.6134453781513, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI224282125, Length=238, Percent_Identity=33.6134453781513, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325049, Length=277, Percent_Identity=34.6570397111913, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 34878; Mature: 34878

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHADVLKVLRKQGYGLVGKHSAVKPCHWCREAIKNGRHCYKAKFYGVESHRCLQMTPTV
CCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECCHH
AWCQQRCVYCWRPVELTVGTHDVPDPDDPDLIVEESVEQQRRFLQGYGHLEGEARKRWKE
HHHHHHHHHEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLEPRHAAISLAGEPTLYPRIGELIDAFHSHGFDTTFLVTNGLRPDRVEELEREPTQLYV
HCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCEEEEE
SLDSPNEELHRQINRPTIPDSWDRIMRTLELLNSLSCRTVIRITAIKGWNMEGTAEEFGE
EECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHEEEEEEEEECCCCCCCHHHHHH
LLADVEPDYVEVKAFMCVGWAAFRMSPDNMPSHEEVRKFAAEIAEHAGFELVDESPPSRV
HHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCE
ALLSS
EEECC
>Mature Secondary Structure
MLHADVLKVLRKQGYGLVGKHSAVKPCHWCREAIKNGRHCYKAKFYGVESHRCLQMTPTV
CCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECCHH
AWCQQRCVYCWRPVELTVGTHDVPDPDDPDLIVEESVEQQRRFLQGYGHLEGEARKRWKE
HHHHHHHHHEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLEPRHAAISLAGEPTLYPRIGELIDAFHSHGFDTTFLVTNGLRPDRVEELEREPTQLYV
HCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCEEEEE
SLDSPNEELHRQINRPTIPDSWDRIMRTLELLNSLSCRTVIRITAIKGWNMEGTAEEFGE
EECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHEEEEEEEEECCCCCCCHHHHHH
LLADVEPDYVEVKAFMCVGWAAFRMSPDNMPSHEEVRKFAAEIAEHAGFELVDESPPSRV
HHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCE
ALLSS
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]