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The map label for this gene is ywoG [H]

Identifier: 19746784

GI number: 19746784

Start: 1595563

End: 1596864

Strand: Reverse

Name: ywoG [H]

Synonym: spyM18_1920

Alternate gene names: 19746784

Gene position: 1596864-1595563 (Counterclockwise)

Preceding gene: 19746787

Following gene: 19746783

Centisome position: 84.27

GC content: 38.48

Gene sequence:

>1302_bases
TTGCTAATGCCCTTTGATAGTAACACTTATATTATACCATTGAAATATATTATATTCTGCTTTTTTTGTAAAATGTTTAT
GAAAATAGAGAGGAGTTCATTTTCAATGGAAGAAAAATTGTTTAACAAACATTTTGTGGCCATCACAGTAATAAACTTTA
TAGTCTATATGGTCTACTATCTTTTTACGGTTATTATTGCCTTTGTGGCGACTAGAGAGCTAGGAGCTCAGACTAGCCAG
GCAGGATTGGCAACAGGGATTTATATTCTAGGGACTTTATTAGCCCGTTTGATTTTTGGAAAGCAGTTGGAGGTGTTTGG
TCGTCGTTTGGTTTTAAGAGGAGGTGCTATTTTTTACCTCTTAACGACCTTAGCCTACTTTTATATGCCAACGATTAGCA
TGATGTACTTGGTTCGTTTCTTAAACGGATTTGGTTATGGTGTGGTATCAACTGCGACAAATACCATTGTAACAGCCTAT
ATTCCAGCTTGTAAAAGAGGAGAAGGAATTAATTTTTATGGCTTGTCAACCAGTCTAGCAGCAGCTATTGGCCCTTTTGT
AGGAACCTTTATGTTGGATAATCTTCATATTGATTTTCGCATGATTATTGTCTTATGTAGCGTCTTGATTGGGTGTGTGG
TTGTTGGTGCTTTTGCTTTTCCAGTCAAAAACATGTCTTTAAATGCGGAGCAATTGGCTAAAACCAAATCGTGGACTGTG
GATAGTTTCATTGAGAAAAAAGCCTTGTTTATCACTGCAATCGCCTTTTTAATGGGGATTGCCTATGCTTCAGTTTTAGG
ATTTCAAAAATTATACACGTCTGAAATTCATTTGACAGCAGTAGGTGCTTATTTCTTTGTGGTCTATGCCTTAATCATTA
CCATCACTCGTCCAGCAATGGGACGTTTAATGGATGCTAAAGGCGATAAATGGGTCTTGTACCCAAGTTATCTTTTTTTA
GCAATGGGACTCTTCTTGCTAGGTAGTGTATCGTCTGGAGGAAGCTATTTGCTTTCAGGAGCCTTGATTGGCTTTGGTTA
TGGCACTTTTATGTCTTGTGGTCAAGCCGCCTCCATACAAGGAGTGGATGAGCATCGCTTTAATACGGCTATGTCTACTT
ATATGATTGGTCTTGATTTAGGTTTAGGTGCTGGGCCTTACCTCTTGGGCTTGATTAAAGATTTGGCACTTGGTAGTGGC
GTGGCTTCCTTTAGGCACTTATTCTGGTTAGCTGCTGTGATTCCACTGATTTGTACCTTGCTTTACTTGTTAAAAACAAA
GACAAGACAGGTTGTGTCTTAA

Upstream 100 bases:

>100_bases
TATGATTATCAATATACCGTTGCAAAATGTGATGATTCACGCTTTTCTCCAAATATTCTTTTACCAATGTATAATTTGTA
TCTTCAAGAGAAATTAACAT

Downstream 100 bases:

>100_bases
GGACAAGAAAAGGAGTTTAGTCTTATACTTAAATACAAACGTATCTTAACAGCTGTAGATAGTTCCTATGAGCCGGGATT
AGCTGTGGGTAAAGCCATTA

Product: antibiotic resistance protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLMPFDSNTYIIPLKYIIFCFFCKMFMKIERSSFSMEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTSQ
AGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYLVRFLNGFGYGVVSTATNTIVTAY
IPACKRGEGINFYGLSTSLAAAIGPFVGTFMLDNLHIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTV
DSFIEKKALFITAIAFLMGIAYASVLGFQKLYTSEIHLTAVGAYFFVVYALIITITRPAMGRLMDAKGDKWVLYPSYLFL
AMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNTAMSTYMIGLDLGLGAGPYLLGLIKDLALGSG
VASFRHLFWLAAVIPLICTLLYLLKTKTRQVVS

Sequences:

>Translated_433_residues
MLMPFDSNTYIIPLKYIIFCFFCKMFMKIERSSFSMEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTSQ
AGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYLVRFLNGFGYGVVSTATNTIVTAY
IPACKRGEGINFYGLSTSLAAAIGPFVGTFMLDNLHIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTV
DSFIEKKALFITAIAFLMGIAYASVLGFQKLYTSEIHLTAVGAYFFVVYALIITITRPAMGRLMDAKGDKWVLYPSYLFL
AMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNTAMSTYMIGLDLGLGAGPYLLGLIKDLALGSG
VASFRHLFWLAAVIPLICTLLYLLKTKTRQVVS
>Mature_433_residues
MLMPFDSNTYIIPLKYIIFCFFCKMFMKIERSSFSMEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTSQ
AGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYLVRFLNGFGYGVVSTATNTIVTAY
IPACKRGEGINFYGLSTSLAAAIGPFVGTFMLDNLHIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTV
DSFIEKKALFITAIAFLMGIAYASVLGFQKLYTSEIHLTAVGAYFFVVYALIITITRPAMGRLMDAKGDKWVLYPSYLFL
AMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNTAMSTYMIGLDLGLGAGPYLLGLIKDLALGSG
VASFRHLFWLAAVIPLICTLLYLLKTKTRQVVS

Specific function: Involved In Sulfonamide (Sulfathiazole) And Bicyclomycin Resistance. Probable Membrane Translocase. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47698; Mature: 47698

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]