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The map label for this gene is glpA [H]

Identifier: 19746595

GI number: 19746595

Start: 1409631

End: 1411469

Strand: Reverse

Name: glpA [H]

Synonym: spyM18_1695

Alternate gene names: 19746595

Gene position: 1411469-1409631 (Counterclockwise)

Preceding gene: 19746596

Following gene: 19746594

Centisome position: 74.48

GC content: 42.52

Gene sequence:

>1839_bases
ATGGAATTTTCAAGAGAAACAAGACGCTTAGCTCTCCAAAAAATGCAAGAAAGAGATTTAGACCTACTGATTATTGGGGG
AGGTATTACGGGTGCTGGTGTGGCACTTCAGGCGGCAGCTAGTGGCCTAGATACGGGTCTGATTGAGATGCAAGATTTTG
CGCAAGGAACCTCTAGCCGTTCAACCAAATTGGTTCACGGGGGGCTTCGTTACTTGAAACAATTTGATGTGGAGGTGGTT
TCAGATACGGTGTCAGAGCGGGCTGTGGTGCAACAAATTGCACCCCACATTCCAAAACCAGACCCTATGTTATTACCTGT
TTATGACGAACCTGGTAGTACCTTTAGCATGTTCCGTTTGAAGGTCGCTATGGATTTGTATGATCTTTTAGCAGGCGTGT
CCAATATGCCAGCGGCCAACAAGGTGTTAACTAAAGAAGAAGTCTTAAAACGAGAACCAGACTTAAAACAAGAAGGCTTG
CTTGGTGGTGGGGTTTACCTTGATTTCCGTAATAATGACGCAAGGCTTGTTATTGAAAATATCAAACGAGCTAATCGTGA
TGGGGCTCTTATTGCTAGTCATGTGAAAGCAGAAGATTTCTTGCTAGATGATAATAGTAAGATTATTGGTGTGAAGGCGC
GTGATTTGCTGTCAGATCAAGAAATCATTATCAAGGCTAAATTAGTCATCAACACCACAGGTCCATGGAGTGATGAGATT
CGTCAATTCTCTCATAAGGGACAACCGATTCATCAAATGCGCCCTACAAAAGGGGTGCATCTGGTAGTGGACCGTCAAAA
ATTACCAGTGTCTCAACCTGTCTATGTTGACACAGGGTTAAATGATGGTCGTATGGTCTTTGTCTTGCCACGTGAAGAAA
AAACTTATTTTGGAACAACGGACACGGACTACACTGGAGACTTGGAGCACCCACAAGTTACTCAAGAAGATGTGGATTAT
TTGTTAGGCGTTGTCAATAACCGCTTTCCAAATGCCAACGTGACCATTGATGATATTGAAAGCAGTTGGGCTGGTCTTCG
CCCCTTGTTATCAGGTAATAGTGCTTCTGACTACAATGGTGGCAACAGCGGTAAAGTCAGTGATGATAGTTTTGATCACT
TGGTTGATACTGTCAAAGCCTATATTAACCACGAAGATAGCCGAGAAGCTGTTGAAAAAGCTATTAAGCAGGTTGAAACC
AGCACATCTGAAAAAGAATTGGATCCGTCTGCAGTGTCACGAGGTTCAAGTTTTGACCGTGATGAGAATGGACTCTTTAC
CTTGGCAGGTGGTAAGATTACCGACTATCGCAAAATGGCTGAAGGAGCATTGACAGGGATTATTCAAATCCTCAAAGAAG
AGTTTGGCAAATCCTTCAAGCTTATCAATTCAAAAACCTATCCTGTTTCAGGAGGTGAAATCAATCCAGCCAATGTAGAT
TCGGAAATAGAAGCCTATGCTCAATTAGGAACTCTTAGTGGTCTTTCGATGGATGATGCTAGGTATTTGGCAAACCTTTA
TGGTTCTAATGCGCCAAAAGTCTTTGCCTTAACTCGTCAATTAACAGCAGCTGAAGGGTTAAGTTTAGCTGAAACCTTGT
CCTTACATTATGCGATGGATTATGAAATGGCTCTTAAACCGACAGATTATTTCTTGAGAAGAACAAATCACCTCTTATTT
ATGCGAGATAGCCTAGATGCTTTGATTGACCCAGTGATTAAAGAAATGGCTAAACATTTTGAATGGTCTGATCAGGAAAG
AGTGGCACAAGAAGACGATCTTCGTCGCGTGATTGCAGACAATGATTTGAGTGCCCTAAAAGGCCAGCAGGAGGGTTAA

Upstream 100 bases:

>100_bases
AAAATTATACAAGGGTTGGAAGCGCGCTGTTAAAGCAACTCAAGTTTTCACTCAAGAAGAAGATGCAGATGACGATGCAA
AATAACTAGAGGAGGATGGA

Downstream 100 bases:

>100_bases
TATGGATATCTTTGGTGAATTTTGGGATACAGCCTTATTGGTTTTACTAGGAAATGGTGTGGTAGCAGGGGTTGTCTTGC
CCAAAACGAAAACCCATGCT

Product: alpha-glycerophosphate oxidase

Products: NA

Alternate protein names: Glycerol-3-phosphate oxidase [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLDTGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVV
SDTVSERAVVQQIAPHIPKPDPMLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNMPAANKVLTKEEVLKREPDLKQEGL
LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNSKIIGVKARDLLSDQEIIIKAKLVINTTGPWSDEI
RQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYVDTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDY
LLGVVNNRFPNANVTIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVEKAIKQVET
STSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQILKEEFGKSFKLINSKTYPVSGGEINPANVD
SEIEAYAQLGTLSGLSMDDARYLANLYGSNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLF
MRDSLDALIDPVIKEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGQQEG

Sequences:

>Translated_612_residues
MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLDTGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVV
SDTVSERAVVQQIAPHIPKPDPMLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNMPAANKVLTKEEVLKREPDLKQEGL
LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNSKIIGVKARDLLSDQEIIIKAKLVINTTGPWSDEI
RQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYVDTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDY
LLGVVNNRFPNANVTIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVEKAIKQVET
STSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQILKEEFGKSFKLINSKTYPVSGGEINPANVD
SEIEAYAQLGTLSGLSMDDARYLANLYGSNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLF
MRDSLDALIDPVIKEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGQQEG
>Mature_612_residues
MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLDTGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVV
SDTVSERAVVQQIAPHIPKPDPMLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNMPAANKVLTKEEVLKREPDLKQEGL
LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNSKIIGVKARDLLSDQEIIIKAKLVINTTGPWSDEI
RQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYVDTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDY
LLGVVNNRFPNANVTIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVEKAIKQVET
STSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQILKEEFGKSFKLINSKTYPVSGGEINPANVD
SEIEAYAQLGTLSGLSMDDARYLANLYGSNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLF
MRDSLDALIDPVIKEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGQQEG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=617, Percent_Identity=30.7941653160454, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI285002231, Length=617, Percent_Identity=30.7941653160454, Blast_Score=251, Evalue=1e-66,
Organism=Escherichia coli, GI2367226, Length=531, Percent_Identity=28.060263653484, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788574, Length=423, Percent_Identity=24.3498817966903, Blast_Score=76, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17509253, Length=601, Percent_Identity=31.7803660565724, Blast_Score=218, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI115534726, Length=608, Percent_Identity=28.4539473684211, Blast_Score=200, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322036, Length=643, Percent_Identity=29.0824261275272, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161077125, Length=524, Percent_Identity=32.2519083969466, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24653942, Length=524, Percent_Identity=32.2519083969466, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24653944, Length=524, Percent_Identity=32.2519083969466, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI20130025, Length=524, Percent_Identity=32.2519083969466, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24586295, Length=520, Percent_Identity=28.6538461538462, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI19921278, Length=614, Percent_Identity=27.0358306188925, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI45550977, Length=460, Percent_Identity=24.7826086956522, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.3.21 [H]

Molecular weight: Translated: 67692; Mature: 67692

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLDTGLIEMQDFAQGTSSR
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCC
STKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDPMLLPVYDEPGSTFSMFRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
KVAMDLYDLLAGVSNMPAANKVLTKEEVLKREPDLKQEGLLGGGVYLDFRNNDARLVIEN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCEEEEEEECCCCEEHHHH
IKRANRDGALIASHVKAEDFLLDDNSKIIGVKARDLLSDQEIIIKAKLVINTTGPWSDEI
HHHCCCCCCEEEECCCCCCEEECCCCCEEEEEHHHHCCCCEEEEEEEEEEECCCCCHHHH
RQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYVDTGLNDGRMVFVLPREEKTYFGTT
HHHHHCCCCHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCCEEEEEEECCCCCEECCC
DTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANVTIDDIESSWAGLRPLLSGNSASDYNG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCHHHCCCCCCCCCC
GNSGKVSDDSFDHLVDTVKAYINHEDSREAVEKAIKQVETSTSEKELDPSAVSRGSSFDR
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHCCCCCCC
DENGLFTLAGGKITDYRKMAEGALTGIIQILKEEFGKSFKLINSKTYPVSGGEINPANVD
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
SEIEAYAQLGTLSGLSMDDARYLANLYGSNAPKVFALTRQLTAAEGLSLAETLSLHYAMD
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHHEEEC
YEMALKPTDYFLRRTNHLLFMRDSLDALIDPVIKEMAKHFEWSDQERVAQEDDLRRVIAD
CEEEECCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NDLSALKGQQEG
CCHHHHCCCCCC
>Mature Secondary Structure
MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLDTGLIEMQDFAQGTSSR
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCC
STKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDPMLLPVYDEPGSTFSMFRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
KVAMDLYDLLAGVSNMPAANKVLTKEEVLKREPDLKQEGLLGGGVYLDFRNNDARLVIEN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCEEEEEEECCCCEEHHHH
IKRANRDGALIASHVKAEDFLLDDNSKIIGVKARDLLSDQEIIIKAKLVINTTGPWSDEI
HHHCCCCCCEEEECCCCCCEEECCCCCEEEEEHHHHCCCCEEEEEEEEEEECCCCCHHHH
RQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYVDTGLNDGRMVFVLPREEKTYFGTT
HHHHHCCCCHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCCEEEEEEECCCCCEECCC
DTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANVTIDDIESSWAGLRPLLSGNSASDYNG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCHHHCCCCCCCCCC
GNSGKVSDDSFDHLVDTVKAYINHEDSREAVEKAIKQVETSTSEKELDPSAVSRGSSFDR
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHCCCCCCC
DENGLFTLAGGKITDYRKMAEGALTGIIQILKEEFGKSFKLINSKTYPVSGGEINPANVD
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
SEIEAYAQLGTLSGLSMDDARYLANLYGSNAPKVFALTRQLTAAEGLSLAETLSLHYAMD
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHHEEEC
YEMALKPTDYFLRRTNHLLFMRDSLDALIDPVIKEMAKHFEWSDQERVAQEDDLRRVIAD
CEEEECCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NDLSALKGQQEG
CCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]