Click here to switch to the map view.

The map label for this gene is lacZ [H]

Identifier: 19746519

GI number: 19746519

Start: 1316334

End: 1319840

Strand: Reverse

Name: lacZ [H]

Synonym: spyM18_1594

Alternate gene names: 19746519

Gene position: 1319840-1316334 (Counterclockwise)

Preceding gene: 19746520

Following gene: 19746518

Centisome position: 69.65

GC content: 43.91

Gene sequence:

>3507_bases
ATGGTTTATCGCCAAAAGAGTTCAGAGATCGTTACAAGGACAATTACCAAGCCATCAAGGGTGACCAGTAACGTTAAACA
GGAGATTGATATGACATCAGATAGCAAGGAGCAGACAGTGACTGGCTACCAATACCACTATATTGATCAAGAAGGAAGAA
AGCAGCCCTTTAATCAAGGCTGGCGTTTTCTTATGGCAGATGTGGCGTGTGCTCAGGACCCTTCTTTTGATGATTCGAAC
TGGCAGGTGATTCATTTACCACATGATTTCAGTCTTACGCAGCCTTACACAAGAAATGGTGAAGCTGAAAGTGCTTATAA
ATTAGGTGGTGTCGGTTGGTATCGGCATTATCTCGTGTTAGATGAGGTTTTAGCTGGTTGTCATGTTGCCATTACTTTTG
AGGGTTCCTATATGGAAACGGAAATTTATGTTAATGGGCAATTCATTGGCAAACACTTAAATGGCTATCAGGAATTTACC
TATGATATCTCTGATGTAGTGATTTTTGGAGCTGAAAATCTTCTGGCTGTCCGGGTTGAAAACAAGGTTCCCAGTTCTCG
TTGGTATTCAGGCAGTGGTCTTTATCGTGAAGTGAGTTTGTCTGTTCTTCCCCAGCTTCATTTTGTGGCAGACCAGGTAG
CAATGACCTTGGCTGATACTGCTGTGCAGGAGAAAGGGCAACAGAAAGTTGATTTACGCTTTGCCCTTAATCAGTCTATT
CAGACTTGCCACTACCAATTGAGCCTCTGTTTATGGGAACAATCACATTGCTCAAAAGACAAGAAACTCCTTTATCAAGA
AACAGAAGTGCCTCTAGCTGATTTGGCTTTCCAAAGACAGTATGGTCTTACACTGTCTTTGGAAGAACTCCAATTGTGGT
CACCAGATAATCCTCACCTCTACGATTTAGAACTCACTCTTTACTATCAAGGTCAGGTCATTGATTGCTTTTGCCTTGAA
ACTGGTTTTCGTCAACTGACTTTTACGGCCAATCAGGGGCTTTTTGTGAATGGCAGAGCTGTCAAATTAAAGGGAGTTTG
TTTGCATCATGACCAAGGAGGCCTAGGAGCTTGTGCTTACGAAGATGCCCTAGCCAGACAATTAGTCCTGTTGAAAGACA
TGGGGGCTAATACCATTCGTAGCACCCATAACCCAAGTAGTCCCAAACTTAGGCAACTAGCCAATCGTCTCGGCTTTTTT
GTGATTGAAGAAGCCTTTGACACCTGGACCTACGCCAAAAATGGAAATGTTAATGACTTTTCAAACTATTTCCATCAGAC
TATCGGAACTGAAAATGCAAACTATCTTCAAAGAGTGAGGTCACCTGAAACGAGCTGGGCCCAGTATAGTATTGAGGCCA
TGGTCTGGTCTGCCAAGAATGACCCGTCAGTGTTGATGTGGTCGATTGGTAATGAATTGATGGAAGGTTTTTCAGCCGGT
GTCAGTCATTACCCAGAGCTGACAAGACAAATGTGCCAATGGATTGCTGCTATTGACACCTCACGTCCCATTACCTTTGG
GGATAATAAATTAAAAGAAGCTGACTTTTGCTGGCATGAAGAAGTGTCGCAAATGGCAACTCTTCTTAGTCAATTAGACC
ATCCCCAGGGACTCATTGGGTTAAACTATGCTAATGGAAAAGACTATGATAAGCTTCATGAGGAGCACTCTGATTGGCTG
TTGTATGGTTCTGAAACAGCCTCAGCCATTACCAGCAGGGCTTATTATAAAGAGACAAAAAAAGTTCTTGACTCCGGTTA
TCACCTAACCTCTTATGATCATGCTAAGGTTGATTGGGGTGCCTTCGCTAGCCAGGCTTGGTATGATACCATTACCCGTG
ATTTTGTTGCTGGCGAATGCGTTTGGACAGGCTTTGATTATTTAGGAGAACCTACCCCCTGGAACAAGATCGACAGCGGT
GTTGTAGGCCTTTGGCCTTCTCCTAAAAATGCCTACTTTGGCATTTTAGACACGGCAGGCTTTCCAAAAGATAGCTATTA
TTTTTACCAAAGTCAGTGGGCGCAGGGGCAGACCACCTTGCACCTGTTACCAGTCTGGCAGAAGGACCAGCTTTGTTTCG
ATGAGCAGGGATTGGTGGAGGTTGTGGTTTATAGCAATGCTGCCAGTGTGCAACTGATGTTTGAAGATGAGCAGGGCAAC
TTAACAGATTATGGAAGGAAGGCATTTCATACTTATAGCACGCCAACGGGACACACTTATCAGCTTTACCAAGGAGCTGA
CGCTGCTAAGAATCCTCACGAGAACCTTTACCTGACTTGGCGAGTGCCCTATCAAAAAGGGTTGCTAAGGGCAGTGGCCT
ACGACATTTCTGGTAAAAGCATTCCAAAAACCAGTGGACGTTCTCAGGTTAGAACCTATGGTTCAGTGGCAAAGCTATCT
TGGAAAGCCTTTGAAGCACCTATTGACGCTCCTTGGGAATTGCTTTATCTGGATTTATCACTCTTGGATAGCCGAGGTGA
ATTGGTCAGCCATGCTCAAGATTGGCTAAAGGTTCAAGTAGAAGGACAAGCCCGTTTGTTGGCTCTTGATAATGGGAATC
CGACTGACCACACCCCTTATCAGGAGCCTCTACGCCAGGCATATGGGGGAAAATTATTAGCCATTTTAGCCCTCACTGGA
GAGGCGGGACACATTAAGGTCACGGCAAAAGCCTCGCAGCAACTTAGCAGTGTTTTTCAGACACAAGTAGCCTGCCGTGC
CCCCAAAGAACACTTAGTGACACTACCTTTAGAGAAATATCAGTTTAAAAAGAGCCGACTGACAAGTCAACAAGAAATTG
GTCAATCTTGTCTAAAGACCACACAATTCCTTTCTGTTTTGGAGAACAAAGACACCCAGCAAAAAGCAGGTAAGGTTAGC
ACACCTCACATTCTTATCACCAGTTACCAGCACTATTTATCTCTGCCCTTGCAGGTTTGTTCTCAGGCATTTGATTTTAA
AAAAGGCGATGATATCTTCTTGCCTCAGTGGCTCCAAGTCAAAGATGCCCAAGGTTCTTTTGTGAAAAAAGCTTTTCCAA
TGACATGGTACCTAAAAGAGAAAATCTTTGCCAAGCCTATTCTTGTCACGGGCTATGTTTCTTGTTTTGGTCAATCAATA
CCGGTTGAGGCAAGGCTTAACCTAGCACAAGCTAGCAAAAGACGGCACCAGGATCTCAGTTTAGTCGCCAAGCAATCCCT
GGCCGCAAGTCAAAAAAGGCTAACTTATTGCTACCAATATGATACGGTGCAAGCCATAGGAGCCATTAGCTTTCAAAATC
ACACAGGCACATCTCTTAGTGTTTCTGTGGCAATCAGTTATGGTAGTCAGAGCTCTATTAAGCAAGAAACCTTGATGCTA
GCTGATAGCCACTTGAGCCAGTTAGAAGAGGTTATTTTCTTCGATGATATTTTGACTGTTTTGTATCTAGCAGTGACCCT
TGAAGTCATTGAAGGACCTGACCTAACTGAAGACAGTATTCAAATTGGCCTTTGGGATTTAGCATGA

Upstream 100 bases:

>100_bases
CAACAGTTATTGCTTTACACCAACCAATCCATCAATGAAATTGCTTATGAAACAGGTTACAATACCAATCATTATTTTAT
CAAGATGTTTAAAAAGTTGA

Downstream 100 bases:

>100_bases
AGCATGAGTAGAAGAAGACTTCTTTGGCACCAGGTCTGATGAATTCTGTAAAATAAGGTATAATAAAAAACAAATAGGCG
TCCTTTATTACGTGAAAGGC

Product: beta-galactosidase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 1168; Mature: 1168

Protein sequence:

>1168_residues
MVYRQKSSEIVTRTITKPSRVTSNVKQEIDMTSDSKEQTVTGYQYHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSN
WQVIHLPHDFSLTQPYTRNGEAESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
YDISDVVIFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLADTAVQEKGQQKVDLRFALNQSI
QTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLAFQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLE
TGFRQLTFTANQGLFVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQLANRLGFF
VIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYSIEAMVWSAKNDPSVLMWSIGNELMEGFSAG
VSHYPELTRQMCQWIAAIDTSRPITFGDNKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWL
LYGSETASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSG
VVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHLLPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGN
LTDYGRKAFHTYSTPTGHTYQLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAKLS
WKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGQARLLALDNGNPTDHTPYQEPLRQAYGGKLLAILALTG
EAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVTLPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVS
TPHILITSYQHYLSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVTGYVSCFGQSI
PVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGAISFQNHTGTSLSVSVAISYGSQSSIKQETLML
ADSHLSQLEEVIFFDDILTVLYLAVTLEVIEGPDLTEDSIQIGLWDLA

Sequences:

>Translated_1168_residues
MVYRQKSSEIVTRTITKPSRVTSNVKQEIDMTSDSKEQTVTGYQYHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSN
WQVIHLPHDFSLTQPYTRNGEAESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
YDISDVVIFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLADTAVQEKGQQKVDLRFALNQSI
QTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLAFQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLE
TGFRQLTFTANQGLFVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQLANRLGFF
VIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYSIEAMVWSAKNDPSVLMWSIGNELMEGFSAG
VSHYPELTRQMCQWIAAIDTSRPITFGDNKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWL
LYGSETASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSG
VVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHLLPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGN
LTDYGRKAFHTYSTPTGHTYQLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAKLS
WKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGQARLLALDNGNPTDHTPYQEPLRQAYGGKLLAILALTG
EAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVTLPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVS
TPHILITSYQHYLSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVTGYVSCFGQSI
PVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGAISFQNHTGTSLSVSVAISYGSQSSIKQETLML
ADSHLSQLEEVIFFDDILTVLYLAVTLEVIEGPDLTEDSIQIGLWDLA
>Mature_1168_residues
MVYRQKSSEIVTRTITKPSRVTSNVKQEIDMTSDSKEQTVTGYQYHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSN
WQVIHLPHDFSLTQPYTRNGEAESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
YDISDVVIFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLADTAVQEKGQQKVDLRFALNQSI
QTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLAFQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLE
TGFRQLTFTANQGLFVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQLANRLGFF
VIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYSIEAMVWSAKNDPSVLMWSIGNELMEGFSAG
VSHYPELTRQMCQWIAAIDTSRPITFGDNKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWL
LYGSETASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSG
VVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHLLPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGN
LTDYGRKAFHTYSTPTGHTYQLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAKLS
WKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGQARLLALDNGNPTDHTPYQEPLRQAYGGKLLAILALTG
EAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVTLPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVS
TPHILITSYQHYLSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVTGYVSCFGQSI
PVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGAISFQNHTGTSLSVSVAISYGSQSSIKQETLML
ADSHLSQLEEVIFFDDILTVLYLAVTLEVIEGPDLTEDSIQIGLWDLA

Specific function: The Wild-Type Enzyme Is An Ineffective Lactase. Two Classes Of Point Mutations Dramatically Improve Activity Of The Enzyme. [C]

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=593, Percent_Identity=22.9342327150084, Blast_Score=91, Evalue=6e-18,
Organism=Escherichia coli, GI48994920, Length=454, Percent_Identity=25.3303964757709, Blast_Score=109, Evalue=1e-24,
Organism=Escherichia coli, GI1786539, Length=396, Percent_Identity=24.7474747474747, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922582, Length=428, Percent_Identity=24.5327102803738, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24655438, Length=428, Percent_Identity=24.5327102803738, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI62471735, Length=428, Percent_Identity=24.5327102803738, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24651745, Length=439, Percent_Identity=23.2346241457859, Blast_Score=87, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 131940; Mature: 131940

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYRQKSSEIVTRTITKPSRVTSNVKQEIDMTSDSKEQTVTGYQYHYIDQEGRKQPFNQG
CCCCCCCCCHHEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHH
WRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEAESAYKLGGVGWYRHYLVL
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHH
DEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFTYDISDVVIFGAENLLAVRVE
HHHHCCCEEEEEEECCEEEEEEEECCEEECCHHCCHHHHEECCCCEEEECCCCEEEEEEC
NKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLADTAVQEKGQQKVDLRFALNQSI
CCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
QTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLAFQRQYGLTLSLEELQLWSPDNPHL
HHHHHEEEEEEECHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEHHHEEECCCCCCEE
YDLELTLYYQGQVIDCFCLETGFRQLTFTANQGLFVNGRAVKLKGVCLHHDQGGLGACAY
EEEEEEEEECCCEEEEEEECCCCEEEEEEECCCEEECCEEEEEEEEEEECCCCCCCCHHH
EDALARQLVLLKDMGANTIRSTHNPSSPKLRQLANRLGFFVIEEAFDTWTYAKNGNVNDF
HHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHCEEEEEHHHHCEEECCCCCCCHH
SNYFHQTIGTENANYLQRVRSPETSWAQYSIEAMVWSAKNDPSVLMWSIGNELMEGFSAG
HHHHHHHCCCCCHHHHHHHCCCCCCHHHEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHH
VSHYPELTRQMCQWIAAIDTSRPITFGDNKLKEADFCWHEEVSQMATLLSQLDHPQGLIG
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LNYANGKDYDKLHEEHSDWLLYGSETASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWG
EECCCCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHH
AFASQAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAG
HHHHHHHHHHHHHHHHCCCEEEECHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCC
FPKDSYYFYQSQWAQGQTTLHLLPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGN
CCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCC
LTDYGRKAFHTYSTPTGHTYQLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKS
CCHHCHHHEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCC
IPKTSGRSQVRTYGSVAKLSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQV
CCCCCCCHHHHHHCCHHHEEHHHHCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHEEEEEE
EGQARLLALDNGNPTDHTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQ
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHH
TQVACRAPKEHLVTLPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVS
HHHHHCCCHHCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
TPHILITSYQHYLSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKE
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEECCCCCHHHHHCCCCEEHHH
KIFAKPILVTGYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQY
HHHHCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
DTVQAIGAISFQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTV
CCHHHHEEEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLAVTLEVIEGPDLTEDSIQIGLWDLA
HHHHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MVYRQKSSEIVTRTITKPSRVTSNVKQEIDMTSDSKEQTVTGYQYHYIDQEGRKQPFNQG
CCCCCCCCCHHEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHH
WRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEAESAYKLGGVGWYRHYLVL
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHH
DEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFTYDISDVVIFGAENLLAVRVE
HHHHCCCEEEEEEECCEEEEEEEECCEEECCHHCCHHHHEECCCCEEEECCCCEEEEEEC
NKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLADTAVQEKGQQKVDLRFALNQSI
CCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
QTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLAFQRQYGLTLSLEELQLWSPDNPHL
HHHHHEEEEEEECHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEHHHEEECCCCCCEE
YDLELTLYYQGQVIDCFCLETGFRQLTFTANQGLFVNGRAVKLKGVCLHHDQGGLGACAY
EEEEEEEEECCCEEEEEEECCCCEEEEEEECCCEEECCEEEEEEEEEEECCCCCCCCHHH
EDALARQLVLLKDMGANTIRSTHNPSSPKLRQLANRLGFFVIEEAFDTWTYAKNGNVNDF
HHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHCEEEEEHHHHCEEECCCCCCCHH
SNYFHQTIGTENANYLQRVRSPETSWAQYSIEAMVWSAKNDPSVLMWSIGNELMEGFSAG
HHHHHHHCCCCCHHHHHHHCCCCCCHHHEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHH
VSHYPELTRQMCQWIAAIDTSRPITFGDNKLKEADFCWHEEVSQMATLLSQLDHPQGLIG
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LNYANGKDYDKLHEEHSDWLLYGSETASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWG
EECCCCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHH
AFASQAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAG
HHHHHHHHHHHHHHHHCCCEEEECHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCC
FPKDSYYFYQSQWAQGQTTLHLLPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGN
CCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCC
LTDYGRKAFHTYSTPTGHTYQLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKS
CCHHCHHHEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCC
IPKTSGRSQVRTYGSVAKLSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQV
CCCCCCCHHHHHHCCHHHEEHHHHCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHEEEEEE
EGQARLLALDNGNPTDHTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQ
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHH
TQVACRAPKEHLVTLPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVS
HHHHHCCCHHCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
TPHILITSYQHYLSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKE
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEECCCCCHHHHHCCCCEEHHH
KIFAKPILVTGYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQY
HHHHCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
DTVQAIGAISFQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTV
CCHHHHEEEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLAVTLEVIEGPDLTEDSIQIGLWDLA
HHHHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA