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The map label for this gene is dps [H]

Identifier: 19746480

GI number: 19746480

Start: 1278250

End: 1278777

Strand: Reverse

Name: dps [H]

Synonym: spyM18_1548

Alternate gene names: 19746480

Gene position: 1278777-1278250 (Counterclockwise)

Preceding gene: 19746482

Following gene: 19746479

Centisome position: 67.48

GC content: 40.34

Gene sequence:

>528_bases
ATGACAAACACACTCGTTGAAAATATTTATGCTTCAGTAACTCACAATATTTCTAAAAAAGAAGCATCAAAAAATGAAAA
AACTAAAGCTGTTTTAAACCAAGCTGTCGCTGACTTATCTGTGGCTGCATCTATTGTGCACCAAGTACACTGGTATATGC
GTGGTCCAGGTTTCTTGTACCTTCACCCAAAAATGGATGAATTACTTGATAGCTTGAATGCTAATTTAGATGAAATGAGC
GAGCGTTTGATCACGATTGGCGGAGCGCCTTATTCTACCCTAGCTGAGTTTTCTAAACACTCTAAATTGGACGAAGCAAA
AGGTACTTACGATAAAACAGTTGCTCAGCATTTAGCAAGATTGGTCGAAGTTTACCTTTACCTCAGCAGCCTTTACCAAG
TTGGTTTGGATATTACCGATGAAGAAGGCGATGCTGGAACAAACGATTTGTTTACAGCAGCTAAGACAGAGGCTGAAAAA
ACCATTTGGATGCTCCAAGCAGAGCGTGGACAAGGCCCAGCACTCTAA

Upstream 100 bases:

>100_bases
GAATAGGATTAGGTCCTTAACCCTTTCTTATGTTTATCACGTTAGGGTTAGTTCCCCCTCCATTCTTGCCCTTTAAGCTG
AAAAGTAAGGAGATGTTATT

Downstream 100 bases:

>100_bases
TTGATTATGCCTTAGGATAAAAGAAGTCAATGATAAAATTGGCTTCTTTTTTATGGAATCATCGATTCATTTTCAGAAAC
ATAGAAAGCGATTCCATACT

Product: peroxide resistance protein

Products: Fe(III); H2O

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMS
ERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
TIWMLQAERGQGPAL

Sequences:

>Translated_175_residues
MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMS
ERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
TIWMLQAERGQGPAL
>Mature_174_residues
TNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSE
RLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEKT
IWMLQAERGQGPAL

Specific function: Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. It binds and incorporates Fe(2+) ion. Effectively inhibits hydroxyl radical formation by the Fenton reaction and is esse

COG id: COG0783

COG function: function code P; DNA-binding ferritin-like protein (oxidative damage protectant)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dps family [H]

Homologues:

None

Paralogues:

None

Copy number: 6720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002177
- InterPro:   IPR023188
- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR008331 [H]

Pfam domain/function: PF00210 Ferritin [H]

EC number: 1.16.3.1

Molecular weight: Translated: 19347; Mature: 19216

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00818 DPS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAASIVHQVHWYMRGPGFLY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLAR
ECCCHHHHHHHHCCCHHHHHHHHEEECCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHH
LVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEKTIWMLQAERGQGPAL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure 
TNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAASIVHQVHWYMRGPGFLY
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSKLDEAKGTYDKTVAQHLAR
ECCCHHHHHHHHCCCHHHHHHHHEEECCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHH
LVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEKTIWMLQAERGQGPAL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe(II); H+; O2

Specific reaction: 4 Fe(II) + 4 H+ + O2 = 4 Fe(III) + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10850989 [H]