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The map label for this gene is 19745297

Identifier: 19745297

GI number: 19745297

Start: 114132

End: 114773

Strand: Reverse

Name: 19745297

Synonym: spyM18_0121

Alternate gene names: NA

Gene position: 114773-114132 (Counterclockwise)

Preceding gene: 19745298

Following gene: 19745291

Centisome position: 6.06

GC content: 39.88

Gene sequence:

>642_bases
ATGTTGATTGTACTAGCTGGAACAATTGGGGCTGGCAAGAGCTCGCTTGCTGCTGCACTTGGAGAGCATTTAGGAACTGA
CGTTTTTTACGAAGCTGTTGATAATAACCCCGTGCTAGACCTCTACTACCAAGACCCTAAAAAGTACGCCTTTTTACTTC
AAATTTATTTTTTGAATAAACGGTTTAAGTCCATCAAAGAAGCTTATCAAGCCGATAACAACATTCTTGACCGCTCTATT
TTTGAAGACGAACTCTTTTTAAAACTTAACTACAAAAATGGCAATGTCACTAAGACAGAACTTGACATCTATCAGGAACT
TCTCGCCAACATGTTAGAAGAACTAGAAGGCATGCCTAAAAAACGCCCTGATCTTCTCATCTACATTGATGTGTCTTTTG
ACAAAATGCTTGAGCGCATTGAAAAACGTGGCCGAAGTTTTGAGCAGGTCGACGGCAATCCTAGTCTTGAGCAATATTAC
CATCAAGTCCACGGTGAATACCCAACCTGGTACGAAGACTACAAGGTCTCTCCAAAAATGAAAATTGATGGCAATTCCCT
TGACTTCGTTCAAAACCCACAAGATTTGGCGACTGTCTTAAAAATGATTGACACCAAACTCAAAGAGCTCCATTTATTAT
AA

Upstream 100 bases:

>100_bases
GGTGCTGCCAAAGTTCGTGGTGCTGTTTCACGCGCTGAGACTCTAGCTGAGGTTGAAGCCATCTTCGAAACAGTACGCTA
ATGACATTAGAAGGAGACGC

Downstream 100 bases:

>100_bases
GAGTTCTAGTGGCCTGATAACCGTTTGTAAGCAAGTAAACCTTAACACTAGCAACAAAAAGAAGTAATACACTAAAAAAA
CACCTTACGAGTATGAACAA

Product: hypothetical protein

Products: NA

Alternate protein names: DGK; DGUO kinase; Deoxynucleoside kinase complex I F-component [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQDPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSI
FEDELFLKLNYKNGNVTKTELDIYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL

Sequences:

>Translated_213_residues
MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQDPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSI
FEDELFLKLNYKNGNVTKTELDIYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL
>Mature_213_residues
MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQDPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSI
FEDELFLKLNYKNGNVTKTELDIYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24717; Mature: 24717

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQDPKKYAFLLQIYFLNK
CEEEEEECCCCCHHHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELDIYQELLANMLEELEGMPK
HHHHHHHHHHCCCCHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
KRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYYHQVHGEYPTWYEDYKVSPKM
CCCCEEEEEECCHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHCCCCCCCCCCEECCCCE
KIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQDPKKYAFLLQIYFLNK
CEEEEEECCCCCHHHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELDIYQELLANMLEELEGMPK
HHHHHHHHHHCCCCHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
KRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYYHQVHGEYPTWYEDYKVSPKM
CCCCEEEEEECCHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHCCCCCCCCCCEECCCCE
KIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896798; 8172906 [H]