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The map label for this gene is pepA [H]

Identifier: 19745291

GI number: 19745291

Start: 109470

End: 110537

Strand: Reverse

Name: pepA [H]

Synonym: spyM18_0115

Alternate gene names: 19745291

Gene position: 110537-109470 (Counterclockwise)

Preceding gene: 19745297

Following gene: 19745290

Centisome position: 5.83

GC content: 45.04

Gene sequence:

>1068_bases
ATGACAGACTTATTCTCAAAAATGAAAGAAGTTACCGAACTGGATGGCATTGCGGGCTATGAACATAGCGTTCGTGACTA
CCTACGCACCAAAATAACCCCGCTGGTTGACCGTGTTGAAACAGACGGGCTTGGTGGCATTTTTGGTATCAGAGATAGTA
AAGTTGAAAAAGCCCCCCGTATTTTAGTAGCTGCGCACATGGACGAAGTCGGTTTTATGGTCAGTGATATCAAAGTTGAC
GGAACGCTACGCGTGGTTGGTATCGGTGGTTGGAACCCACTTGTTGTCAGTTCACAACGGTTTACCCTTTACACACGCAC
TGGCCAAGTTATTCCCCTTATTTCAGGATCGGTACCTCCCCATTTTTTACGTGGGGCAAATGGCTCTGCTAGTCTACCAC
ATATCGAAGATATTGTGTTTGATGGTGGCTTTACGGATAAGGCAGAAGCTGAAAGATTTGGTATTACACCGGGTGATATT
ATTGTCCCTCAATCTGAAACGATCCTAACAGCCAATCAAAAAAATATTATTTCAAAAGCTTGGGACAATCGCTATGGCGT
TCTCATGATAACAGAAATGCTTGAAGCGTTAAAAGGACAAGACCTTAACAACACCCTAATTGCAGGTGCTAACGTTCAAG
AAGAAGTTGGTCTGCGCGGAGCCCACGTCTCAACCACCAAGTTCGACCCTGAACTCTTTTTCGCAGTAGATTGTTCGCCT
GCTGGTGATATTTATGGCAATTCTGGAACAATCGGAGATGGTACCTTATTGCGTTTCTACGACCCAGGCCATGTCATGCT
CAAGGATATGCGTGACTTCTTACTCACAACGGCTGAGGAAGCTGGTGTCAATATCCAATACTATTGTGGCAAGGGAGGCA
CAGATGCAGGTGCTGCACATCTTCAAAATGGTGGTGTCCCATCAACAACCATCGGAGTCTGTGCACGCTACATTCACTCT
CATCAAACCCTCTACGCTATGGATGATTTCGTAGAAGCCCAAGCCTTCTTACAAGCCATTATCAAAAAACTGGATCGCTC
AACCGTTGACTTGATTAAATGTTACTAA

Upstream 100 bases:

>100_bases
TTTTTCTTTGCTGTGAAACCCATTCTTACTTAAAAAGTGGTAGAATATAGGGAGATGACCGCGTTGAACTGGTCTGAAAC
CTTGTAAATGGAGATGAAAA

Downstream 100 bases:

>100_bases
ACTAGCATTAGCCTGATTAACCATAATATCCCACAAGGAGCAACAGAATGAAAATTGGCATTATTGGTGTTGGCAAAATG
GCTAGCGCTATCATCAAAGG

Product: glutamyl-aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTDLFSKMKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGLGGIFGIRDSKVEKAPRILVAAHMDEVGFMVSDIKVD
GTLRVVGIGGWNPLVVSSQRFTLYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDI
IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGLRGAHVSTTKFDPELFFAVDCSP
AGDIYGNSGTIGDGTLLRFYDPGHVMLKDMRDFLLTTAEEAGVNIQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHS
HQTLYAMDDFVEAQAFLQAIIKKLDRSTVDLIKCY

Sequences:

>Translated_355_residues
MTDLFSKMKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGLGGIFGIRDSKVEKAPRILVAAHMDEVGFMVSDIKVD
GTLRVVGIGGWNPLVVSSQRFTLYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDI
IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGLRGAHVSTTKFDPELFFAVDCSP
AGDIYGNSGTIGDGTLLRFYDPGHVMLKDMRDFLLTTAEEAGVNIQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHS
HQTLYAMDDFVEAQAFLQAIIKKLDRSTVDLIKCY
>Mature_354_residues
TDLFSKMKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGLGGIFGIRDSKVEKAPRILVAAHMDEVGFMVSDIKVDG
TLRVVGIGGWNPLVVSSQRFTLYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDII
VPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGLRGAHVSTTKFDPELFFAVDCSPA
GDIYGNSGTIGDGTLLRFYDPGHVMLKDMRDFLLTTAEEAGVNIQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSH
QTLYAMDDFVEAQAFLQAIIKKLDRSTVDLIKCY

Specific function: Unknown

COG id: COG1363

COG function: function code G; Cellulase M and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M42 family [H]

Homologues:

Organism=Escherichia coli, GI1790332, Length=349, Percent_Identity=29.7994269340974, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1788727, Length=351, Percent_Identity=30.7692307692308, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87082417, Length=354, Percent_Identity=27.683615819209, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017538
- InterPro:   IPR008007 [H]

Pfam domain/function: PF05343 Peptidase_M42 [H]

EC number: =3.4.11.7 [H]

Molecular weight: Translated: 38567; Mature: 38436

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLFSKMKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGLGGIFGIRDSKVEKAPR
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHCCE
ILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFTLYTRTGQVIPLISGSVPP
EEEEECHHHHCEEEEEEEECCEEEEEEECCCCCEEEECCEEEEEEECCCEEEEECCCCCH
HFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDIIVPQSETILTANQKNIISKA
HHHCCCCCCCCCCCHHHEEECCCCCCCCCHHHCCCCCCCEECCCCCEEEECCHHHHHHHH
WDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGLRGAHVSTTKFDPELFFAVDCSP
HCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCCEEECCCCCCEEEEEEECCC
AGDIYGNSGTIGDGTLLRFYDPGHVMLKDMRDFLLTTAEEAGVNIQYYCGKGGTDAGAAH
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHH
LQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQAFLQAIIKKLDRSTVDLIKCY
HCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHEECC
>Mature Secondary Structure 
TDLFSKMKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGLGGIFGIRDSKVEKAPR
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHCCE
ILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFTLYTRTGQVIPLISGSVPP
EEEEECHHHHCEEEEEEEECCEEEEEEECCCCCEEEECCEEEEEEECCCEEEEECCCCCH
HFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDIIVPQSETILTANQKNIISKA
HHHCCCCCCCCCCCHHHEEECCCCCCCCCHHHCCCCCCCEECCCCCEEEECCHHHHHHHH
WDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGLRGAHVSTTKFDPELFFAVDCSP
HCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCCEEECCCCCCEEEEEEECCC
AGDIYGNSGTIGDGTLLRFYDPGHVMLKDMRDFLLTTAEEAGVNIQYYCGKGGTDAGAAH
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHH
LQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQAFLQAIIKKLDRSTVDLIKCY
HCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535515 [H]