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The map label for this gene is tatD [H]

Identifier: 197294724

GI number: 197294724

Start: 700406

End: 701173

Strand: Direct

Name: tatD [H]

Synonym: PAa_0690

Alternate gene names: 197294724

Gene position: 700406-701173 (Clockwise)

Preceding gene: 197294723

Following gene: 197294733

Centisome position: 79.6

GC content: 31.51

Gene sequence:

>768_bases
ATGTTAATAGATACCCATGCACATCTGAATGTTGCAAATTATGACAAAGATTTAGACGAAGTTTTAAAAAGGGCTTTTCA
AAATGATGTCAAAAAAATGATTGTAGTCGGAATGGATCAAAAAAGCAATCAAAAAGCTTTTGAGATAGCTAACAAATACA
AAGAAATAATGGTCTCTTTTGGGATTCATCCTTGTTCAGAATTTCCAAAAGAAACCTCAGAAAGTATTATTAAATACCTC
AAGCATCCTCAAACAGTTGCTGTTGGCGAAATTGGACTAGATTTACATCATCGACAAGACAATTTAGATATTCAAAAAAA
GATTTTTCAAGAACAAGTCAAAATAGCAATTCAATATAATTTACCAATCATCATTCATGCTCGTAAAGCTTTTGAAGATG
TTTATCGTTTGTTGTTGCCTTTTAAAAACCAAATTAGAGGGGTTTTTCATTGTTTGGTTTTTAGCAGTAAAGAAGTTCAA
ATGGCTTTGGAATTAGGTTTTTATATAGGAATTGGCGGGGTTGTAACTTTTGAAAATATTCCAGTGGCAGCAACAATTGC
CAAAAACACTCCTTTAAATAAAATCTTATTAGAAACAGATTCTCCTTATTTAACCCCTTATCCTTTCAAAGGGAAAAGAA
ACGAACCCGCAAACATTAAAATTATTGCTCAAAAAATAGCTCAATTAAAAAACCTTTCTTTGCAAGAGGTAGCGCAACAA
ACAAGTAATAATGTCGCTCAACTTTTTTGCAACAAAACCTCTTTTTGA

Upstream 100 bases:

>100_bases
AATTGAAAAAATTATTTAGTTAGTTTAGTTTAATTTGAAAATTATGAAAAAAACTTTGTAGTTTTCAAAAATTAAAAATA
AGAATAAAAAGGTATAAAAA

Downstream 100 bases:

>100_bases
GTTTTTATTTTGGCAATTATATAGAGTCTTTTTTTGCTACCTTTAAAAAGGAGTGAATGCGATTTTACGACCTTAGAAAA
GTTAGCAAAGATTAATTAAT

Product: Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLIDTHAHLNVANYDKDLDEVLKRAFQNDVKKMIVVGMDQKSNQKAFEIANKYKEIMVSFGIHPCSEFPKETSESIIKYL
KHPQTVAVGEIGLDLHHRQDNLDIQKKIFQEQVKIAIQYNLPIIIHARKAFEDVYRLLLPFKNQIRGVFHCLVFSSKEVQ
MALELGFYIGIGGVVTFENIPVAATIAKNTPLNKILLETDSPYLTPYPFKGKRNEPANIKIIAQKIAQLKNLSLQEVAQQ
TSNNVAQLFCNKTSF

Sequences:

>Translated_255_residues
MLIDTHAHLNVANYDKDLDEVLKRAFQNDVKKMIVVGMDQKSNQKAFEIANKYKEIMVSFGIHPCSEFPKETSESIIKYL
KHPQTVAVGEIGLDLHHRQDNLDIQKKIFQEQVKIAIQYNLPIIIHARKAFEDVYRLLLPFKNQIRGVFHCLVFSSKEVQ
MALELGFYIGIGGVVTFENIPVAATIAKNTPLNKILLETDSPYLTPYPFKGKRNEPANIKIIAQKIAQLKNLSLQEVAQQ
TSNNVAQLFCNKTSF
>Mature_255_residues
MLIDTHAHLNVANYDKDLDEVLKRAFQNDVKKMIVVGMDQKSNQKAFEIANKYKEIMVSFGIHPCSEFPKETSESIIKYL
KHPQTVAVGEIGLDLHHRQDNLDIQKKIFQEQVKIAIQYNLPIIIHARKAFEDVYRLLLPFKNQIRGVFHCLVFSSKEVQ
MALELGFYIGIGGVVTFENIPVAATIAKNTPLNKILLETDSPYLTPYPFKGKRNEPANIKIIAQKIAQLKNLSLQEVAQQ
TSNNVAQLFCNKTSF

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=29.5454545454545, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=29.5454545454545, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI226061853, Length=269, Percent_Identity=28.996282527881, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=29.5719844357977, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI14042943, Length=274, Percent_Identity=26.2773722627737, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI225903424, Length=222, Percent_Identity=27.4774774774775, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI225903439, Length=250, Percent_Identity=25.2, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787342, Length=252, Percent_Identity=33.7301587301587, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=33.0739299610895, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082439, Length=253, Percent_Identity=29.2490118577075, Blast_Score=126, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17559024, Length=278, Percent_Identity=29.8561151079137, Blast_Score=133, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=28.1368821292776, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=194, Percent_Identity=32.4742268041237, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=30.3738317757009, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=29.9651567944251, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24586117, Length=280, Percent_Identity=30, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221330018, Length=280, Percent_Identity=30, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 29012; Mature: 29012

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDTHAHLNVANYDKDLDEVLKRAFQNDVKKMIVVGMDQKSNQKAFEIANKYKEIMVSF
CEECCCCCEEEHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHC
GIHPCSEFPKETSESIIKYLKHPQTVAVGEIGLDLHHRQDNLDIQKKIFQEQVKIAIQYN
CCCCCHHCHHHHHHHHHHHHCCCCEEEEEHCCCEEECCCCCCHHHHHHHHHHHEEEEEEC
LPIIIHARKAFEDVYRLLLPFKNQIRGVFHCLVFSSKEVQMALELGFYIGIGGVVTFENI
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCEEEECCC
PVAATIAKNTPLNKILLETDSPYLTPYPFKGKRNEPANIKIIAQKIAQLKNLSLQEVAQQ
CEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
TSNNVAQLFCNKTSF
HCCHHHHHHCCCCCC
>Mature Secondary Structure
MLIDTHAHLNVANYDKDLDEVLKRAFQNDVKKMIVVGMDQKSNQKAFEIANKYKEIMVSF
CEECCCCCEEEHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHC
GIHPCSEFPKETSESIIKYLKHPQTVAVGEIGLDLHHRQDNLDIQKKIFQEQVKIAIQYN
CCCCCHHCHHHHHHHHHHHHCCCCEEEEEHCCCEEECCCCCCHHHHHHHHHHHEEEEEEC
LPIIIHARKAFEDVYRLLLPFKNQIRGVFHCLVFSSKEVQMALELGFYIGIGGVVTFENI
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCEEEECCC
PVAATIAKNTPLNKILLETDSPYLTPYPFKGKRNEPANIKIIAQKIAQLKNLSLQEVAQQ
CEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
TSNNVAQLFCNKTSF
HCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]