Click here to switch to the map view.

The map label for this gene is yacO [H]

Identifier: 197294706

GI number: 197294706

Start: 672761

End: 673462

Strand: Reverse

Name: yacO [H]

Synonym: PAa_0672

Alternate gene names: 197294706

Gene position: 673462-672761 (Counterclockwise)

Preceding gene: 197294707

Following gene: 197294705

Centisome position: 76.53

GC content: 28.49

Gene sequence:

>702_bases
ATGTTTATTTATGGAAAAAACACAATCAAAGAAGCAATTAAAGCTAAAAGAAAAATTTACCAATTATATCTTGATGCTAA
TTTTAAAGACAATTCTTTTATTTCTTTTTTGAAACTATCTAATCAACCTTATCAATTGGTTGATAAAAAAAAATTATTTG
ATTTAGTCAAGCAAAAAAACCATCAAGGAGTAGTTGCTCAAGTAGAAAGTTATCAATTTTATGATTTAGATAGTTTTTTA
TCGTTTGAAAAAAAGCAACGCTTTTTGATTTTAGATGCTATTCATGATCCTCATAATTTGGGAGCCATTTTAAGAACAGT
TGAGGCTTGTGGTTTTGATGGAGTGATTATGAGCAAAAAACATCAAGTTCCTTTAAATGCTACAGTTTCCAAAATTGCTT
GCGGTGCTTTGGAATATGTCAAAGTTTTTTTAGTTTCAAATCTCCATCAAACTATTTTAAAATTACAAAAACAACAAGTT
TTAATTATTGGAACTGATAGCAATGCCACGCAAACCTTAACTAAAATTCCTTGTAACCAGTCTTTGGCGATTATTGTTGG
CAATGAAGGTGACGGCATACGTTATTTATTAAAACAAAAATGCGATTTATTGGTTAAAATACCTATGAAAGGGAAAATTA
ATTCTTTAAATGTTAGTGTGGCTTCTGCTTTGATGATGTATGCTACTTTATTATCTTATTGA

Upstream 100 bases:

>100_bases
TTATCTTTTTTGATTAGTTTTTTGAATGTTAAGAATTTTTTTAATTTCCAAAAATTTTTTAATTTTAAAAATGTCAAAAA
AGTAGAAAAGAAGTTTTAAG

Downstream 100 bases:

>100_bases
ACTTTAATTTTCTTTTTGCTAATTTTACTAAAAAAACAAATCATTATTTATCTTTTCTTTGCCTCAAAACATTAATTTAT
GATATAATAAAAAAAGATGT

Product: tRNA/rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MFIYGKNTIKEAIKAKRKIYQLYLDANFKDNSFISFLKLSNQPYQLVDKKKLFDLVKQKNHQGVVAQVESYQFYDLDSFL
SFEKKQRFLILDAIHDPHNLGAILRTVEACGFDGVIMSKKHQVPLNATVSKIACGALEYVKVFLVSNLHQTILKLQKQQV
LIIGTDSNATQTLTKIPCNQSLAIIVGNEGDGIRYLLKQKCDLLVKIPMKGKINSLNVSVASALMMYATLLSY

Sequences:

>Translated_233_residues
MFIYGKNTIKEAIKAKRKIYQLYLDANFKDNSFISFLKLSNQPYQLVDKKKLFDLVKQKNHQGVVAQVESYQFYDLDSFL
SFEKKQRFLILDAIHDPHNLGAILRTVEACGFDGVIMSKKHQVPLNATVSKIACGALEYVKVFLVSNLHQTILKLQKQQV
LIIGTDSNATQTLTKIPCNQSLAIIVGNEGDGIRYLLKQKCDLLVKIPMKGKINSLNVSVASALMMYATLLSY
>Mature_233_residues
MFIYGKNTIKEAIKAKRKIYQLYLDANFKDNSFISFLKLSNQPYQLVDKKKLFDLVKQKNHQGVVAQVESYQFYDLDSFL
SFEKKQRFLILDAIHDPHNLGAILRTVEACGFDGVIMSKKHQVPLNATVSKIACGALEYVKVFLVSNLHQTILKLQKQQV
LIIGTDSNATQTLTKIPCNQSLAIIVGNEGDGIRYLLKQKCDLLVKIPMKGKINSLNVSVASALMMYATLLSY

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=238, Percent_Identity=28.1512605042017, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1790623, Length=233, Percent_Identity=35.1931330472103, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788935, Length=230, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790083, Length=146, Percent_Identity=34.2465753424658, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555908, Length=247, Percent_Identity=24.6963562753036, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324775, Length=162, Percent_Identity=35.1851851851852, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26295; Mature: 26295

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIYGKNTIKEAIKAKRKIYQLYLDANFKDNSFISFLKLSNQPYQLVDKKKLFDLVKQKN
CEEECCHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
HQGVVAQVESYQFYDLDSFLSFEKKQRFLILDAIHDPHNLGAILRTVEACGFDGVIMSKK
CCCEEEEECCEEEECHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCC
HQVPLNATVSKIACGALEYVKVFLVSNLHQTILKLQKQQVLIIGTDSNATQTLTKIPCNQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHEECCCCC
SLAIIVGNEGDGIRYLLKQKCDLLVKIPMKGKINSLNVSVASALMMYATLLSY
CEEEEECCCCCHHHHHHHHCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFIYGKNTIKEAIKAKRKIYQLYLDANFKDNSFISFLKLSNQPYQLVDKKKLFDLVKQKN
CEEECCHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
HQGVVAQVESYQFYDLDSFLSFEKKQRFLILDAIHDPHNLGAILRTVEACGFDGVIMSKK
CCCEEEEECCEEEECHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCC
HQVPLNATVSKIACGALEYVKVFLVSNLHQTILKLQKQQVLIIGTDSNATQTLTKIPCNQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHEECCCCC
SLAIIVGNEGDGIRYLLKQKCDLLVKIPMKGKINSLNVSVASALMMYATLLSY
CEEEEECCCCCHHHHHHHHCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]