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The map label for this gene is hrcA

Identifier: 197294601

GI number: 197294601

Start: 567716

End: 568738

Strand: Reverse

Name: hrcA

Synonym: PAa_0557

Alternate gene names: 197294601

Gene position: 568738-567716 (Counterclockwise)

Preceding gene: 197294602

Following gene: 197294600

Centisome position: 64.63

GC content: 27.76

Gene sequence:

>1023_bases
ATGCTTTCAGATAGAAAAAAAATAATTTTAAAGGCGGTAGTAGAAAGCTACTCCCAAAAAAGACAACCAGTAGGTTCCAA
ATCATTAATTCATTTGCCTGAGCTTCAATTTTCTAGTGCTACTATTCGTTATGATATGTTAAAATTAGAAGAAGAAGGTT
TTTTAAAAAAAAATCATACTTCAAGCGGAAGAATTCCTTCATTTAAAGGCTACACTTATTATTTAACTCATTTATTAACT
AGAGACTATGATGCAGCCAATTCGTTTCCTTTGATTGATAAGGTTATTCAAAACAAAACTTTTCATAAAAACAAAGTAAT
TAAAGAGGCAATAAAATTACTTAATAGTTTAACTAGTTATACAGCTATGGCGATTGGACCCGATGTTTTTAACAATAGTA
AGATCAGCAAAATTGATTTTATTCCTTTAAATCACAAGCAGGCTTTGATTTTAATTATCACTAACAAAGGTGATGTTCAA
CATCAAAATATTTCTTTAGATCAAACAAAAGAAATTAGTATTTATGATTTAAAAGATATAGTCAAAATTATCAGTGATTT
GTTAGTGGGAAAATATTTATCAGAAGCTGTTAAAATTATTCAAAGTGATTTTGTTAAACAAACGATTGCAAAATATATTC
GTTTTCAAGAGCAATTGATTGCCTTGTTTATTGAAGCCTTTAGTAGTTTTGCTTCAGAAAACACCTATTTTGCAGGAATT
TCTGAGATGACTAAAAAAAAAGAATTTAGCGACTTAGAATTAATTAAAAAAATTATGAATTTGTTAGAACGCAAAGAGTT
GTTAAAAATTTTGTTGAATCAAGAAGGTTTATCCTTTAAATTATCAGATGAATTGCAACTAACTCCCGTTAAAGATTATA
TGATTTTGTCTATACCTTTTGCTATTGATGCCAACGAAAAGGGGACAATTGCTATTTTGGGACCTTCTTGGATGAAATAT
CCTAAAATTATTCCCCTTTTAGAATATTTATCAATTCATTTATCAAAATTAAACCAGGAATAA

Upstream 100 bases:

>100_bases
TTATTTTTTAACCATCAATCAAAAAAATGGTTGACATTGTAATCAAAAAAGCATATAATATTATTGGCAATCATTACTAT
GAGTGCTAAAGGTGTTAATT

Downstream 100 bases:

>100_bases
ATTAAAAATATTTACGAAAGGGGCTAAAAATGTTATTTGAAGAAAAAGAAGAAAAAAATAATTGTCAAGCTTGCGATGTT
TGCGATGACAATGAAAAAAA

Product: Heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLSDRKKIILKAVVESYSQKRQPVGSKSLIHLPELQFSSATIRYDMLKLEEEGFLKKNHTSSGRIPSFKGYTYYLTHLLT
RDYDAANSFPLIDKVIQNKTFHKNKVIKEAIKLLNSLTSYTAMAIGPDVFNNSKISKIDFIPLNHKQALILIITNKGDVQ
HQNISLDQTKEISIYDLKDIVKIISDLLVGKYLSEAVKIIQSDFVKQTIAKYIRFQEQLIALFIEAFSSFASENTYFAGI
SEMTKKKEFSDLELIKKIMNLLERKELLKILLNQEGLSFKLSDELQLTPVKDYMILSIPFAIDANEKGTIAILGPSWMKY
PKIIPLLEYLSIHLSKLNQE

Sequences:

>Translated_340_residues
MLSDRKKIILKAVVESYSQKRQPVGSKSLIHLPELQFSSATIRYDMLKLEEEGFLKKNHTSSGRIPSFKGYTYYLTHLLT
RDYDAANSFPLIDKVIQNKTFHKNKVIKEAIKLLNSLTSYTAMAIGPDVFNNSKISKIDFIPLNHKQALILIITNKGDVQ
HQNISLDQTKEISIYDLKDIVKIISDLLVGKYLSEAVKIIQSDFVKQTIAKYIRFQEQLIALFIEAFSSFASENTYFAGI
SEMTKKKEFSDLELIKKIMNLLERKELLKILLNQEGLSFKLSDELQLTPVKDYMILSIPFAIDANEKGTIAILGPSWMKY
PKIIPLLEYLSIHLSKLNQE
>Mature_340_residues
MLSDRKKIILKAVVESYSQKRQPVGSKSLIHLPELQFSSATIRYDMLKLEEEGFLKKNHTSSGRIPSFKGYTYYLTHLLT
RDYDAANSFPLIDKVIQNKTFHKNKVIKEAIKLLNSLTSYTAMAIGPDVFNNSKISKIDFIPLNHKQALILIITNKGDVQ
HQNISLDQTKEISIYDLKDIVKIISDLLVGKYLSEAVKIIQSDFVKQTIAKYIRFQEQLIALFIEAFSSFASENTYFAGI
SEMTKKKEFSDLELIKKIMNLLERKELLKILLNQEGLSFKLSDELQLTPVKDYMILSIPFAIDANEKGTIAILGPSWMKY
PKIIPLLEYLSIHLSKLNQE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_PHYAS (B1VAB8)

Other databases:

- EMBL:   AM422018
- RefSeq:   YP_001799142.1
- ProteinModelPortal:   B1VAB8
- SMR:   B1VAB8
- GeneID:   6799119
- GenomeReviews:   AM422018_GR
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   CLSK343843
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38931; Mature: 38931

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDRKKIILKAVVESYSQKRQPVGSKSLIHLPELQFSSATIRYDMLKLEEEGFLKKNHT
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEHHHHHCCCCCCCCCCCC
SSGRIPSFKGYTYYLTHLLTRDYDAANSFPLIDKVIQNKTFHKNKVIKEAIKLLNSLTSY
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TAMAIGPDVFNNSKISKIDFIPLNHKQALILIITNKGDVQHQNISLDQTKEISIYDLKDI
HHHHCCCHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCEECCCCCCCCCCEEEECHHHH
VKIISDLLVGKYLSEAVKIIQSDFVKQTIAKYIRFQEQLIALFIEAFSSFASENTYFAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECH
SEMTKKKEFSDLELIKKIMNLLERKELLKILLNQEGLSFKLSDELQLTPVKDYMILSIPF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEEEE
AIDANEKGTIAILGPSWMKYPKIIPLLEYLSIHLSKLNQE
EEECCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSDRKKIILKAVVESYSQKRQPVGSKSLIHLPELQFSSATIRYDMLKLEEEGFLKKNHT
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEHHHHHCCCCCCCCCCCC
SSGRIPSFKGYTYYLTHLLTRDYDAANSFPLIDKVIQNKTFHKNKVIKEAIKLLNSLTSY
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TAMAIGPDVFNNSKISKIDFIPLNHKQALILIITNKGDVQHQNISLDQTKEISIYDLKDI
HHHHCCCHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCEECCCCCCCCCCEEEECHHHH
VKIISDLLVGKYLSEAVKIIQSDFVKQTIAKYIRFQEQLIALFIEAFSSFASENTYFAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECH
SEMTKKKEFSDLELIKKIMNLLERKELLKILLNQEGLSFKLSDELQLTPVKDYMILSIPF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEEEE
AIDANEKGTIAILGPSWMKYPKIIPLLEYLSIHLSKLNQE
EEECCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA