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The map label for this gene is ung [H]

Identifier: 197294566

GI number: 197294566

Start: 513652

End: 514296

Strand: Reverse

Name: ung [H]

Synonym: PAa_0521

Alternate gene names: 197294566

Gene position: 514296-513652 (Counterclockwise)

Preceding gene: 197294567

Following gene: 197294565

Centisome position: 58.45

GC content: 29.15

Gene sequence:

>645_bases
ATGTGGAAAAAAATTATTGATTTACAAAGAAAAAAAGATTATTTTCAAAATATAGCTCAATTTTTAAAAGCAGAAAAAAT
GAAAAATAAAGTTATTTACCCTGAGACAAAAGACATTTTTACAGCCTTTCATCTAACCGCTTTTCATAAAGTAAAAGCAG
TAATTTTAGGACAAGACCCTTATCATGGCGAAAACCAAGCACATGGTTTATCTTTTAGCGTGAAAGGGCAAAAACGTCCC
CCAACCCTTAATAATATTTTTAAAGAATTAAAAAATGATTTAAACATTGAAAGCCATCAAAATAATTTAACCCCTTGGGC
TTTAGAAGGAGTTTTAATGTTGAATTCTATTTTAACTGTTCAAAAAAATAAACCTTTGAGTCATCAAAACATTGGTTGGC
AAACTTTTACTCAAATTATTTTAGAAAGCTTGCAAACGAAAAAAAATGTAGTTTATCTTTTGTGGGGTAAATTTGCTCAA
ACTTATGAAAAATACATTATTTCTCAAAATAATTACATTATCAAAAGCCCTCATCCTTCCCCCTTTTCTGCTGCTAACGG
TTTTTTTGGCTCTAAACATTTTTCCAAAACTAACCTTTACCTTAAATCACACAATATCCAAGAAATTAATTGGCAGCTTC
ACTAA

Upstream 100 bases:

>100_bases
GTTTTTGCCATTATTTATTTAATTGTTATGTTTGTACTTTTAGGAATTATTAAAAAAAATTGGAATCAAGCGGATGAATA
ATTAAAAGGTAAAAAGTTTC

Downstream 100 bases:

>100_bases
TTTTTTAAAGATTTATTTATAACAAAAAATAATGAATTGAAGCATTTAAATGAAAAATAAATGGGCACATTTCATCAATT
AAATTTTGTTAGTAAAAACT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MWKKIIDLQRKKDYFQNIAQFLKAEKMKNKVIYPETKDIFTAFHLTAFHKVKAVILGQDPYHGENQAHGLSFSVKGQKRP
PTLNNIFKELKNDLNIESHQNNLTPWALEGVLMLNSILTVQKNKPLSHQNIGWQTFTQIILESLQTKKNVVYLLWGKFAQ
TYEKYIISQNNYIIKSPHPSPFSAANGFFGSKHFSKTNLYLKSHNIQEINWQLH

Sequences:

>Translated_214_residues
MWKKIIDLQRKKDYFQNIAQFLKAEKMKNKVIYPETKDIFTAFHLTAFHKVKAVILGQDPYHGENQAHGLSFSVKGQKRP
PTLNNIFKELKNDLNIESHQNNLTPWALEGVLMLNSILTVQKNKPLSHQNIGWQTFTQIILESLQTKKNVVYLLWGKFAQ
TYEKYIISQNNYIIKSPHPSPFSAANGFFGSKHFSKTNLYLKSHNIQEINWQLH
>Mature_214_residues
MWKKIIDLQRKKDYFQNIAQFLKAEKMKNKVIYPETKDIFTAFHLTAFHKVKAVILGQDPYHGENQAHGLSFSVKGQKRP
PTLNNIFKELKNDLNIESHQNNLTPWALEGVLMLNSILTVQKNKPLSHQNIGWQTFTQIILESLQTKKNVVYLLWGKFAQ
TYEKYIISQNNYIIKSPHPSPFSAANGFFGSKHFSKTNLYLKSHNIQEINWQLH

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI6224979, Length=215, Percent_Identity=41.3953488372093, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI19718751, Length=215, Percent_Identity=41.3953488372093, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1788934, Length=214, Percent_Identity=42.9906542056075, Blast_Score=186, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17556304, Length=215, Percent_Identity=45.5813953488372, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6323620, Length=223, Percent_Identity=40.8071748878924, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24954; Mature: 24954

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKKIIDLQRKKDYFQNIAQFLKAEKMKNKVIYPETKDIFTAFHLTAFHKVKAVILGQDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCC
YHGENQAHGLSFSVKGQKRPPTLNNIFKELKNDLNIESHQNNLTPWALEGVLMLNSILTV
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QKNKPLSHQNIGWQTFTQIILESLQTKKNVVYLLWGKFAQTYEKYIISQNNYIIKSPHPS
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCC
PFSAANGFFGSKHFSKTNLYLKSHNIQEINWQLH
CCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MWKKIIDLQRKKDYFQNIAQFLKAEKMKNKVIYPETKDIFTAFHLTAFHKVKAVILGQDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCC
YHGENQAHGLSFSVKGQKRPPTLNNIFKELKNDLNIESHQNNLTPWALEGVLMLNSILTV
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QKNKPLSHQNIGWQTFTQIILESLQTKKNVVYLLWGKFAQTYEKYIISQNNYIIKSPHPS
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEECCCCC
PFSAANGFFGSKHFSKTNLYLKSHNIQEINWQLH
CCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA