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The map label for this gene is nfo [H]

Identifier: 197294506

GI number: 197294506

Start: 444382

End: 444633

Strand: Reverse

Name: nfo [H]

Synonym: PAa_0448

Alternate gene names: 197294506

Gene position: 444633-444382 (Counterclockwise)

Preceding gene: 197294507

Following gene: 197294492

Centisome position: 50.53

GC content: 37.3

Gene sequence:

>252_bases
ATGTTAATTTTAGGAAGTCATGTACCCATGCAAAAGCCAGATAATTTTAAAGGTTCTGTCAAAACCGCTTTGGCTATGAG
GGCCAATAGTTTCATGGTTTATAGCGGGGCCCCGAAAAATACTATTAGAAAAGAACAAGACAAATCCCAAATCAAAGAAG
CATTAGAACTTGCTTTTCAAAATAATTTATTCTGCGATAATTTCGTGGGACATGCTCCTTATATCGTCAATCTTGCCAAT
GGTGATCCCTGA

Upstream 100 bases:

>100_bases
CGTTTTGTTTCAAACAAAAATTCAAAACCCAAAACAAAAAAACAATTTGGCAAAAAACAAAAAAATAAATTATAGTAAAA
AATACTAAGGAGCAGTTGAA

Downstream 100 bases:

>100_bases
AAAAAGAGCTTTTGCAATTAATTTTTTATCCCAAGAATTAAATCGTTTTGCTGCAATGAAAATTAATAAAATGGTTTTGC
ATCCAGGAAATTTTTTAAAA

Product: Putative endonuclease IV, fragment

Products: NA

Alternate protein names: Endodeoxyribonuclease IV; Endonuclease IV [H]

Number of amino acids: Translated: 83; Mature: 83

Protein sequence:

>83_residues
MLILGSHVPMQKPDNFKGSVKTALAMRANSFMVYSGAPKNTIRKEQDKSQIKEALELAFQNNLFCDNFVGHAPYIVNLAN
GDP

Sequences:

>Translated_83_residues
MLILGSHVPMQKPDNFKGSVKTALAMRANSFMVYSGAPKNTIRKEQDKSQIKEALELAFQNNLFCDNFVGHAPYIVNLAN
GDP
>Mature_83_residues
MLILGSHVPMQKPDNFKGSVKTALAMRANSFMVYSGAPKNTIRKEQDKSQIKEALELAFQNNLFCDNFVGHAPYIVNLAN
GDP

Specific function: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by ble

COG id: COG0648

COG function: function code L; Endonuclease IV

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AP endonuclease 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018246
- InterPro:   IPR001719
- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =3.1.21.2 [H]

Molecular weight: Translated: 9183; Mature: 9183

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILGSHVPMQKPDNFKGSVKTALAMRANSFMVYSGAPKNTIRKEQDKSQIKEALELAFQ
CEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCHHHCHHHHHHHHHHHHHHHC
NNLFCDNFVGHAPYIVNLANGDP
CCCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MLILGSHVPMQKPDNFKGSVKTALAMRANSFMVYSGAPKNTIRKEQDKSQIKEALELAFQ
CEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCHHHCHHHHHHHHHHHHHHHC
NNLFCDNFVGHAPYIVNLANGDP
CCCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA