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The map label for this gene is pgi [H]

Identifier: 197294303

GI number: 197294303

Start: 198665

End: 199948

Strand: Direct

Name: pgi [H]

Synonym: PAa_0166

Alternate gene names: 197294303

Gene position: 198665-199948 (Clockwise)

Preceding gene: 197294302

Following gene: 197294316

Centisome position: 22.58

GC content: 29.91

Gene sequence:

>1284_bases
GTGAGCTTAAAATTAAATCTTAGTGGAATTGCATCTTTTTGTGATTGGGAAAAAATCACAAAAGAATATAAAAATAAAAT
AAAAGATATTCATTATAAATTACATAATGAAACACTTCTTCAAAATCAATATTTAGGGTGGTTAGATTTGCCTTTAAATT
ATGATCAAGAAGAATTTGCAAGAATGAAACAATTAAAAAATCAAAACAATGATCTAGATGTTTTAGTAGTTGTAGGAATT
GGAGGCTCTTATTTAGGAGCAAAAGCAGGAATTGAATTTCTTCAAACTCCTTTTCAAAATAACAAACCAGAAATTATTTT
TGCAGGACATCAAGTATCAGGAACTTATTTAACTAATCTTTTAAAATATTTACAAGACAAAACTTGGGCCATCAACGTTA
TTTCAAAATCAGGCACCACTTTAGAACCGGCTTTAGCTTTTCGAATTCTTAAAGAAGCAATTGAAAAAAAATATGGTCAA
GAAGCTGCGAAAAAACGTATTTTTGCTACCACAGATAAACAAAAAGGAACTTTATTTAATTTATCCAAAAAACAAGGGTA
TGAAATGTTTGTGATTCCTGATTCTGTTGGCGGAAGATTTAGTGTTTTAACTAGTGTAGGACTTTTGCCTTTTGTTTTTG
CTAATTTAGATGTGGACGCTATATTAAAAGGCGCTTTACAAGCTTTCAAAGATACTTCTTCAGATGATTTAGATCAAAAC
CAAGCCTATCAATATGCTTTAGCTAGATGTTGTATGTATTCTCAAATGAATAAAAACGTAGAGTTGTTAGTTACTTATGA
ACCTTCTTTACTAGCTTTTGCAGAATGGTGGAAGCAATTATTTGCTGAATCAGAAGGAAAAGACAAAAAAGGTCTTTTTG
TGGGCTCTGTAAATAATTCTTCTGATCTTCATTCTTTAGGACAATACATCCAAGAAGGAAAAAAAATATGTTTTGAAACA
GTTTTGAACTTCCTTTCTACAAAAGATGAATGTGTTGTTCCTGAAATAAGCAATGAATTAGATAATCTTAATTACATAGC
TAATAAAACTTATTCAGAAATTAATCAAATAATCCTTCAAGCAACTAAACAAGCTCACATCGAAGGAGAAGTCCCTAATT
TAGAGATTGTTGTTTCTTCTTTGGATGCATTTCATTTAGGTTATTTAATGTACTTTTTCCAAAAAGCATGCGCTATGTCA
GGTTTGCTATTAGGAGTAAACCCTTTCAACCAACCAGGTGTGGAAATATATAAACAAAAAATGTTTTCTTTGTTGAAAAA
ATAA

Upstream 100 bases:

>100_bases
ACAACGGTTATCTTTATTTCTTTTTTGAGTAAAAATAAGGCCAAAAATCGTCAACAACAAAAATAAGAAAAAATTTTATT
TAAAAATTAAGGAGTTTATC

Downstream 100 bases:

>100_bases
AGAATATATTGAGTTTTTAAATTTAATTTTAAAGATCGACTTTTTAGTCGGTCTTTTTTTATAAAAAAACCATTTTATTT
AAAAAAATTCAGTCAACAAC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSLKLNLSGIASFCDWEKITKEYKNKIKDIHYKLHNETLLQNQYLGWLDLPLNYDQEEFARMKQLKNQNNDLDVLVVVGI
GGSYLGAKAGIEFLQTPFQNNKPEIIFAGHQVSGTYLTNLLKYLQDKTWAINVISKSGTTLEPALAFRILKEAIEKKYGQ
EAAKKRIFATTDKQKGTLFNLSKKQGYEMFVIPDSVGGRFSVLTSVGLLPFVFANLDVDAILKGALQAFKDTSSDDLDQN
QAYQYALARCCMYSQMNKNVELLVTYEPSLLAFAEWWKQLFAESEGKDKKGLFVGSVNNSSDLHSLGQYIQEGKKICFET
VLNFLSTKDECVVPEISNELDNLNYIANKTYSEINQIILQATKQAHIEGEVPNLEIVVSSLDAFHLGYLMYFFQKACAMS
GLLLGVNPFNQPGVEIYKQKMFSLLKK

Sequences:

>Translated_427_residues
MSLKLNLSGIASFCDWEKITKEYKNKIKDIHYKLHNETLLQNQYLGWLDLPLNYDQEEFARMKQLKNQNNDLDVLVVVGI
GGSYLGAKAGIEFLQTPFQNNKPEIIFAGHQVSGTYLTNLLKYLQDKTWAINVISKSGTTLEPALAFRILKEAIEKKYGQ
EAAKKRIFATTDKQKGTLFNLSKKQGYEMFVIPDSVGGRFSVLTSVGLLPFVFANLDVDAILKGALQAFKDTSSDDLDQN
QAYQYALARCCMYSQMNKNVELLVTYEPSLLAFAEWWKQLFAESEGKDKKGLFVGSVNNSSDLHSLGQYIQEGKKICFET
VLNFLSTKDECVVPEISNELDNLNYIANKTYSEINQIILQATKQAHIEGEVPNLEIVVSSLDAFHLGYLMYFFQKACAMS
GLLLGVNPFNQPGVEIYKQKMFSLLKK
>Mature_426_residues
SLKLNLSGIASFCDWEKITKEYKNKIKDIHYKLHNETLLQNQYLGWLDLPLNYDQEEFARMKQLKNQNNDLDVLVVVGIG
GSYLGAKAGIEFLQTPFQNNKPEIIFAGHQVSGTYLTNLLKYLQDKTWAINVISKSGTTLEPALAFRILKEAIEKKYGQE
AAKKRIFATTDKQKGTLFNLSKKQGYEMFVIPDSVGGRFSVLTSVGLLPFVFANLDVDAILKGALQAFKDTSSDDLDQNQ
AYQYALARCCMYSQMNKNVELLVTYEPSLLAFAEWWKQLFAESEGKDKKGLFVGSVNNSSDLHSLGQYIQEGKKICFETV
LNFLSTKDECVVPEISNELDNLNYIANKTYSEINQIILQATKQAHIEGEVPNLEIVVSSLDAFHLGYLMYFFQKACAMSG
LLLGVNPFNQPGVEIYKQKMFSLLKK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=378, Percent_Identity=23.2804232804233, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 48237; Mature: 48106

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKLNLSGIASFCDWEKITKEYKNKIKDIHYKLHNETLLQNQYLGWLDLPLNYDQEEFA
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCHHHHH
RMKQLKNQNNDLDVLVVVGIGGSYLGAKAGIEFLQTPFQNNKPEIIFAGHQVSGTYLTNL
HHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
LKYLQDKTWAINVISKSGTTLEPALAFRILKEAIEKKYGQEAAKKRIFATTDKQKGTLFN
HHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCEEEECCCCCCCEEE
LSKKQGYEMFVIPDSVGGRFSVLTSVGLLPFVFANLDVDAILKGALQAFKDTSSDDLDQN
EHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHH
QAYQYALARCCMYSQMNKNVELLVTYEPSLLAFAEWWKQLFAESEGKDKKGLFVGSVNNS
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
SDLHSLGQYIQEGKKICFETVLNFLSTKDECVVPEISNELDNLNYIANKTYSEINQIILQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATKQAHIEGEVPNLEIVVSSLDAFHLGYLMYFFQKACAMSGLLLGVNPFNQPGVEIYKQK
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHH
MFSLLKK
HHHHHCC
>Mature Secondary Structure 
SLKLNLSGIASFCDWEKITKEYKNKIKDIHYKLHNETLLQNQYLGWLDLPLNYDQEEFA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCHHHHH
RMKQLKNQNNDLDVLVVVGIGGSYLGAKAGIEFLQTPFQNNKPEIIFAGHQVSGTYLTNL
HHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
LKYLQDKTWAINVISKSGTTLEPALAFRILKEAIEKKYGQEAAKKRIFATTDKQKGTLFN
HHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCEEEECCCCCCCEEE
LSKKQGYEMFVIPDSVGGRFSVLTSVGLLPFVFANLDVDAILKGALQAFKDTSSDDLDQN
EHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHH
QAYQYALARCCMYSQMNKNVELLVTYEPSLLAFAEWWKQLFAESEGKDKKGLFVGSVNNS
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
SDLHSLGQYIQEGKKICFETVLNFLSTKDECVVPEISNELDNLNYIANKTYSEINQIILQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATKQAHIEGEVPNLEIVVSSLDAFHLGYLMYFFQKACAMSGLLLGVNPFNQPGVEIYKQK
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHH
MFSLLKK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA