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The map label for this gene is nrnA [H]

Identifier: 197294185

GI number: 197294185

Start: 22997

End: 23938

Strand: Reverse

Name: nrnA [H]

Synonym: PAa_0019

Alternate gene names: 197294185

Gene position: 23938-22997 (Counterclockwise)

Preceding gene: 197294186

Following gene: 197294184

Centisome position: 2.72

GC content: 26.65

Gene sequence:

>942_bases
ATGAAGTTAATCCAAGAAAAAATTAAATTTTTTGATACTATTATTATCCACGGACATAAAAGACCAGACGGCGATTCTTA
TGGAGCGCAATTTGGATTAAAAAACATGTTGCAAACAACTTTTCCTGAGAAAAAAGTTTATGCAGTTGGCGAAGAAAACC
TGAATTTGTCTTTTTTAGGAACAATGGATAAAATAACTGATGATGTTTATAAAAATGCTTTGGTTTTTGTTGTTGATTCT
GGTGACACCAAAAATATTAGTGATCAAAGATTTCAGCTAGGTAAATTTATTATTCGAATTGACCATCATATTTTAATATC
AAATTATGGAAATTATGAATGGGTTGATGATTCTTTTGGTTCTTGTTCTGAGATGATCTACCTTCTCAAAGAAAAATTAA
ATTTAAAATTAACTTATTTAGGTGCTTTGGCTATTTATGTAGGAATATTGACTGATAGTGGTAATTTTCGTTTTAATCGT
GTGAGTAGCCAAACTTTTCGCATTGCATCCGAATTATTAAATTATGGTATTGATGTGACTTGGGTGGAAAAAAAAGTCAA
AAAAGAAAAGCTTAATGTTGTAAAATATAAAGGTTATGTATGTCAAAATATTGTTGTAGCAAAAAATTTTGTTTATGTTT
ATGTTTCTCAAAAAACAATGCAAAAATTTAATTTAACCTTGGAAGAGTCTTTTTCTGCTATTAATTTGTTATTGTATATA
GAAAATTACTATTTTTATATTCTTTTTTTAGAAATGAATAACCAAAAAATTAAAGTTCGTCTTTGTTCTAATGGACCTCA
TATTTATCATGTTGTTAAAAAATACGGTTTTAAAGGTCATTTAAGTGCATGTAGTTTGCTTTTATCTTCTTTTCAAGAAA
TTGAACCGTTTATAAAATCGCTAGAAAAAGATTTATCTATTTATTTAAAACAACTTAAGTAA

Upstream 100 bases:

>100_bases
TTGTTTGGGAAAATAAAAATACTATTTTTTTATATTTTTCATGTTGTAATTATTTTTTGTTATTTTCTAATCTCTAAATA
ATTAAAAGGAATAAAAAAAG

Downstream 100 bases:

>100_bases
TATTTATAAAAAATTTCAGAAAGGGTTATTTTATGATTAAAATTAATCTTTTAAATCATCAAAGCCATTCATTTCCTTCC
AAAACAACTCCTTTGGAAAT

Product: Exopolyphosphatase-related protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKLIQEKIKFFDTIIIHGHKRPDGDSYGAQFGLKNMLQTTFPEKKVYAVGEENLNLSFLGTMDKITDDVYKNALVFVVDS
GDTKNISDQRFQLGKFIIRIDHHILISNYGNYEWVDDSFGSCSEMIYLLKEKLNLKLTYLGALAIYVGILTDSGNFRFNR
VSSQTFRIASELLNYGIDVTWVEKKVKKEKLNVVKYKGYVCQNIVVAKNFVYVYVSQKTMQKFNLTLEESFSAINLLLYI
ENYYFYILFLEMNNQKIKVRLCSNGPHIYHVVKKYGFKGHLSACSLLLSSFQEIEPFIKSLEKDLSIYLKQLK

Sequences:

>Translated_313_residues
MKLIQEKIKFFDTIIIHGHKRPDGDSYGAQFGLKNMLQTTFPEKKVYAVGEENLNLSFLGTMDKITDDVYKNALVFVVDS
GDTKNISDQRFQLGKFIIRIDHHILISNYGNYEWVDDSFGSCSEMIYLLKEKLNLKLTYLGALAIYVGILTDSGNFRFNR
VSSQTFRIASELLNYGIDVTWVEKKVKKEKLNVVKYKGYVCQNIVVAKNFVYVYVSQKTMQKFNLTLEESFSAINLLLYI
ENYYFYILFLEMNNQKIKVRLCSNGPHIYHVVKKYGFKGHLSACSLLLSSFQEIEPFIKSLEKDLSIYLKQLK
>Mature_313_residues
MKLIQEKIKFFDTIIIHGHKRPDGDSYGAQFGLKNMLQTTFPEKKVYAVGEENLNLSFLGTMDKITDDVYKNALVFVVDS
GDTKNISDQRFQLGKFIIRIDHHILISNYGNYEWVDDSFGSCSEMIYLLKEKLNLKLTYLGALAIYVGILTDSGNFRFNR
VSSQTFRIASELLNYGIDVTWVEKKVKKEKLNVVKYKGYVCQNIVVAKNFVYVYVSQKTMQKFNLTLEESFSAINLLLYI
ENYYFYILFLEMNNQKIKVRLCSNGPHIYHVVKKYGFKGHLSACSLLLSSFQEIEPFIKSLEKDLSIYLKQLK

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 36302; Mature: 36302

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIQEKIKFFDTIIIHGHKRPDGDSYGAQFGLKNMLQTTFPEKKVYAVGEENLNLSFLG
CCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEC
TMDKITDDVYKNALVFVVDSGDTKNISDQRFQLGKFIIRIDHHILISNYGNYEWVDDSFG
CHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHEEEEEEEEEEEECCCCCCCCCCCCC
SCSEMIYLLKEKLNLKLTYLGALAIYVGILTDSGNFRFNRVSSQTFRIASELLNYGIDVT
CHHHHHHHHHHHHCEEEEHHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCEE
WVEKKVKKEKLNVVKYKGYVCQNIVVAKNFVYVYVSQKTMQKFNLTLEESFSAINLLLYI
EHHHHHHHHHCCEEEECCCHHCCEEEECCEEEEEEEHHHHHHHCCCHHHCHHHEEEEEEE
ENYYFYILFLEMNNQKIKVRLCSNGPHIYHVVKKYGFKGHLSACSLLLSSFQEIEPFIKS
ECEEEEEEEEEECCCEEEEEEECCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LEKDLSIYLKQLK
HHHHHHHHHHHCC
>Mature Secondary Structure
MKLIQEKIKFFDTIIIHGHKRPDGDSYGAQFGLKNMLQTTFPEKKVYAVGEENLNLSFLG
CCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEC
TMDKITDDVYKNALVFVVDSGDTKNISDQRFQLGKFIIRIDHHILISNYGNYEWVDDSFG
CHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHEEEEEEEEEEEECCCCCCCCCCCCC
SCSEMIYLLKEKLNLKLTYLGALAIYVGILTDSGNFRFNRVSSQTFRIASELLNYGIDVT
CHHHHHHHHHHHHCEEEEHHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCEE
WVEKKVKKEKLNVVKYKGYVCQNIVVAKNFVYVYVSQKTMQKFNLTLEESFSAINLLLYI
EHHHHHHHHHCCEEEECCCHHCCEEEECCEEEEEEEHHHHHHHCCCHHHCHHHEEEEEEE
ENYYFYILFLEMNNQKIKVRLCSNGPHIYHVVKKYGFKGHLSACSLLLSSFQEIEPFIKS
ECEEEEEEEEEECCCEEEEEEECCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LEKDLSIYLKQLK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]