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The map label for this gene is cheW-1 [H]

Identifier: 197120302

GI number: 197120302

Start: 4478516

End: 4479013

Strand: Direct

Name: cheW-1 [H]

Synonym: Gbem_3941

Alternate gene names: 197120302

Gene position: 4478516-4479013 (Clockwise)

Preceding gene: 197120299

Following gene: 197120303

Centisome position: 97.04

GC content: 57.23

Gene sequence:

>498_bases
ATGGAGACCGCACTCACGAAGGTTAAAAGCGAGGAATATGGGGGTGAGCTGATCCAGTTGGTGAGCTTCAACCTCGAAAA
AGAGGAGTACGGCATCAACGTCCTGATGGTGCGGGAGATCATACGCATGCTTAACATCACCCGCGTCCCCAACACCCCGC
ACTACGTGGAAGGGGTGATCAACCTGCGCGGCAAGGTGATCCCTATCATCAACCTGCGCAAGAAGTTCGATCTGGTGGAC
TCGGAATACGACAAAAGAACCCGGATCATGGTCATGGAGGTAGTCGGCGAGCTGATGGGATTCATCGTCGACGAGGTCTC
CGAGGTGATCCGTATCTCCGAAAAGGAGATCCAGCCCCCGCCCCCGGCGGTTTCCAGCGGCATCGAGCAGGAATGCATGG
CCGGGGTCATCAACCAGGCCGACCGGCTACTCGTTCTGCTCGACTTGGAGCGGATGTTCTCCGCCGACGAGCGCAGGCTG
TTCAGCAACGTAGGTTAA

Upstream 100 bases:

>100_bases
AAAAAAATATTCAACCTTTGGTTCAGCATACCGAATAGGAAACTAATGCGGCGGGAGCCTGGCTTCCGCCGCCTATGATT
TCACCGCACAGGGAGGGTCC

Downstream 100 bases:

>100_bases
GGTACCAACAGGGGAAAGCCTTCCCCCTTCCCGGAGCGCATCATGGCTATAGACTGCGAAGATCAGGAGCTACTCGAAGG
TTTCCTTGCGGAAACCACGG

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
METALTKVKSEEYGGELIQLVSFNLEKEEYGINVLMVREIIRMLNITRVPNTPHYVEGVINLRGKVIPIINLRKKFDLVD
SEYDKRTRIMVMEVVGELMGFIVDEVSEVIRISEKEIQPPPPAVSSGIEQECMAGVINQADRLLVLLDLERMFSADERRL
FSNVG

Sequences:

>Translated_165_residues
METALTKVKSEEYGGELIQLVSFNLEKEEYGINVLMVREIIRMLNITRVPNTPHYVEGVINLRGKVIPIINLRKKFDLVD
SEYDKRTRIMVMEVVGELMGFIVDEVSEVIRISEKEIQPPPPAVSSGIEQECMAGVINQADRLLVLLDLERMFSADERRL
FSNVG
>Mature_165_residues
METALTKVKSEEYGGELIQLVSFNLEKEEYGINVLMVREIIRMLNITRVPNTPHYVEGVINLRGKVIPIINLRKKFDLVD
SEYDKRTRIMVMEVVGELMGFIVDEVSEVIRISEKEIQPPPPAVSSGIEQECMAGVINQADRLLVLLDLERMFSADERRL
FSNVG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=163, Percent_Identity=35.5828220858896, Blast_Score=113, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18809; Mature: 18809

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METALTKVKSEEYGGELIQLVSFNLEKEEYGINVLMVREIIRMLNITRVPNTPHYVEGVI
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NLRGKVIPIINLRKKFDLVDSEYDKRTRIMVMEVVGELMGFIVDEVSEVIRISEKEIQPP
HCCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPAVSSGIEQECMAGVINQADRLLVLLDLERMFSADERRLFSNVG
CCHHHCCHHHHHHHHHHCCHHHEEHEEEHHHHHCHHHHHHHHCCC
>Mature Secondary Structure
METALTKVKSEEYGGELIQLVSFNLEKEEYGINVLMVREIIRMLNITRVPNTPHYVEGVI
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NLRGKVIPIINLRKKFDLVDSEYDKRTRIMVMEVVGELMGFIVDEVSEVIRISEKEIQPP
HCCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPAVSSGIEQECMAGVINQADRLLVLLDLERMFSADERRLFSNVG
CCHHHCCHHHHHHHHHHCCHHHEEHEEEHHHHHCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]