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The map label for this gene is arnC [H]

Identifier: 197120224

GI number: 197120224

Start: 4401103

End: 4401816

Strand: Direct

Name: arnC [H]

Synonym: Gbem_3863

Alternate gene names: 197120224

Gene position: 4401103-4401816 (Clockwise)

Preceding gene: 197120181

Following gene: 197120225

Centisome position: 95.36

GC content: 61.62

Gene sequence:

>714_bases
ATGAGCACGATCTCCATCGTCATACCTGCGCATAACGAGGAAGGCAACATAGGAACGTTGGTGCAGGAAATTCTTGCCAC
CCGGCTCGAATGCGAGATCATCGTGGTCGACGACGCCAGTACCGACGAAACCCACCAAACGCTTCTCGCGCTGAAAAGGA
CGGTCCCCTCGCTGAAGATCGTCCAGCACGACCGCTCCTACGGCCAGAGCGCCGCCGTCGCTACCGGGATCAGGCATGCC
AGCGGAGAGCTCATCGCCACCATGGACGGCGACGGGCAAAACGACCCGGCCGACATCCCGAAGATGGTGCAGGCGCTCAT
GAAAAGCGGCGACAAAAACCTCAGGATGGTCGCGGGGTTCCGCAAAAAGCGCGACGACGCGGCCTGGCGCATCATCTGCT
CCAAGATCGCCAACGCCTATCGCCGCTTTTTCTTGAGGGACGAGACCCCCGACACCGGCTGCGGTCTCAAGGTGTTCTAC
CGCTCGGCGTTTTTGAACCTCCCCTTCTTCGACCACATGCACCGCTTCCTCCCGGCCCTGATCAAGATGCAGGGGGGCGA
GGTGGTCTCGGTCGAGGTGGAGCACCGCGCCAGGACCCACGGCGTCTCGAAGTATGGGACGCTGAACCGGCTCTGGGTCG
GCATCGTCGACATCTTAGGCGTCTGCTGGCTGCGCATGAGGGCCAAGAACGTGAAGATCACGAGGTGCGACTGA

Upstream 100 bases:

>100_bases
GGTGAGAAAATTCTAGTATTGTCCGTGGCGGTTGTGTTATTTTGCCGAGTTGCCGATTTCCCCGCAAGACAATGGTAAAC
GACCAAGGACCGAGGACTTA

Downstream 100 bases:

>100_bases
TGGTAATGTCCGAAAAAATTTGGGTTGGGATAGGGCTTTCCGGCCAGTTCTTCTTCACCATGCGCTTCGTGGTGCAGTGG
ATCGCCACCGAAAGGAACCG

Product: family glycosyltransferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSTISIVIPAHNEEGNIGTLVQEILATRLECEIIVVDDASTDETHQTLLALKRTVPSLKIVQHDRSYGQSAAVATGIRHA
SGELIATMDGDGQNDPADIPKMVQALMKSGDKNLRMVAGFRKKRDDAAWRIICSKIANAYRRFFLRDETPDTGCGLKVFY
RSAFLNLPFFDHMHRFLPALIKMQGGEVVSVEVEHRARTHGVSKYGTLNRLWVGIVDILGVCWLRMRAKNVKITRCD

Sequences:

>Translated_237_residues
MSTISIVIPAHNEEGNIGTLVQEILATRLECEIIVVDDASTDETHQTLLALKRTVPSLKIVQHDRSYGQSAAVATGIRHA
SGELIATMDGDGQNDPADIPKMVQALMKSGDKNLRMVAGFRKKRDDAAWRIICSKIANAYRRFFLRDETPDTGCGLKVFY
RSAFLNLPFFDHMHRFLPALIKMQGGEVVSVEVEHRARTHGVSKYGTLNRLWVGIVDILGVCWLRMRAKNVKITRCD
>Mature_236_residues
STISIVIPAHNEEGNIGTLVQEILATRLECEIIVVDDASTDETHQTLLALKRTVPSLKIVQHDRSYGQSAAVATGIRHAS
GELIATMDGDGQNDPADIPKMVQALMKSGDKNLRMVAGFRKKRDDAAWRIICSKIANAYRRFFLRDETPDTGCGLKVFYR
SAFLNLPFFDHMHRFLPALIKMQGGEVVSVEVEHRARTHGVSKYGTLNRLWVGIVDILGVCWLRMRAKNVKITRCD

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788588, Length=230, Percent_Identity=28.2608695652174, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787259, Length=94, Percent_Identity=36.1702127659575, Blast_Score=65, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585265, Length=210, Percent_Identity=28.0952380952381, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 26490; Mature: 26359

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTISIVIPAHNEEGNIGTLVQEILATRLECEIIVVDDASTDETHQTLLALKRTVPSLKI
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEE
VQHDRSYGQSAAVATGIRHASGELIATMDGDGQNDPADIPKMVQALMKSGDKNLRMVAGF
ECCCHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHH
RKKRDDAAWRIICSKIANAYRRFFLRDETPDTGCGLKVFYRSAFLNLPFFDHMHRFLPAL
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
IKMQGGEVVSVEVEHRARTHGVSKYGTLNRLWVGIVDILGVCWLRMRAKNVKITRCD
HHCCCCCEEEEEEHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
>Mature Secondary Structure 
STISIVIPAHNEEGNIGTLVQEILATRLECEIIVVDDASTDETHQTLLALKRTVPSLKI
CEEEEEEECCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEE
VQHDRSYGQSAAVATGIRHASGELIATMDGDGQNDPADIPKMVQALMKSGDKNLRMVAGF
ECCCHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHH
RKKRDDAAWRIICSKIANAYRRFFLRDETPDTGCGLKVFYRSAFLNLPFFDHMHRFLPAL
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
IKMQGGEVVSVEVEHRARTHGVSKYGTLNRLWVGIVDILGVCWLRMRAKNVKITRCD
HHCCCCCEEEEEEHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12219091 [H]