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The map label for this gene is glnS [H]

Identifier: 197120160

GI number: 197120160

Start: 4337539

End: 4339236

Strand: Direct

Name: glnS [H]

Synonym: Gbem_3799

Alternate gene names: 197120160

Gene position: 4337539-4339236 (Clockwise)

Preceding gene: 197120159

Following gene: 197120161

Centisome position: 93.98

GC content: 62.49

Gene sequence:

>1698_bases
ATGACCGACACCAAGACAGCAGAAGCCTCGGCCCCCGAAAAGGCCGCCAACTTCATCAGGAACATCGTCACCGACGACCT
TAAAAACGGCAAGCACACCGGCATCGTCACCCGGTTCCCGCCGGAGCCCAACGGTTACCTGCACATAGGGCACGCGAAGT
CGATCTGCCTCAACTTCGGTCTCGCGCTTGACTTCGGCGGGCGCTGCCACCTGCGCTTCGACGACACCAACCCCACCAAA
GAAGACATCGAGTACGAGGACTCCATCAAGGAGAACGTGAAGTGGCTCGGCTTCGACTGGGGCCAGCACATGTACTACGC
CTCGAACTACTTCGAGCAGTTCTACAACTATGCGGTGCTCTTGATCGAGAAAGGGCTGGCCTACGTCGATTCCCTCTCGG
CAGACGAGATGCGGGCCCTGCGCGGCACGCTGAACGAGCCGGGCAAGGAAAGCCCGTACCGCAGCCGCGGCGTCGAGGAG
AACCTCGACCTCTTCCGCCGCATGCGCGCCGGCGAGTTCGAAGAGGGATCCAACGTCCTCAGGCTGAAGATCGACATGGC
GTCGCCCAACATCAACCTGCGCGACCCGGTCATCTACCGCATCCGCAAGGTAGAGCACCACCGAACCGGCGACGCCTGGT
GCATCTACCCGATGTACGACTACGCGCACTGCATCTCCGACGCCATCGAGGGGATCACCCACTCCGTCTGCACCCTTGAG
TTCGAGGACCACCGCCCGCTCTACGACTGGGTGCTGGACCAGCTTCCGGTCAAATGCCACCCACAGCAGATCGAGTTCGC
CCGGCTGAATCTGAGCTACACCGTGATGAGCAAGAGAAAGCTTCTGGAACTGGTGCAGGAGAAGCTGGTCGACGGCTGGG
ACGACCCGCGCATGCCGACCCTGGTCGGCCTGAGAAGACGCGGCTTCACTCCGCAGTCCATCGTCAACTTCTGCGAGACC
ATCGGCGTGGGCAAGAGCGACAGCTTCATCGACATGAGCATCCTGGAAGAGTCGGTGCGCGAGGACCTGAACGTCCGCGC
CCCGCGCGCCATGTCCGTGCTGCGCCCGCTGAAGCTCGTCATAGAGGGGTACCCGGAAGGGGAAAGCGAGGAATTCGAGG
CAGCTAACCACCCCAACGATCCGGAAATGGGAACGCGCAAGGTTCCCTTCTCCAAGACCGTCTACATCGAAAGGGACGAC
TTCCAGGAGGAGCCCGCCAAGGGTTTCTTCCGCCTGGCCCCCGGCCGCGAAGTGCGGCTTCGCTACGCCTACATCATCCG
CTGCGAATCGGTGGTTAAGGATGAAAACGGGGAGATCGTCGAGGTCCGCTGCAGCTACGACACCGGTTCCCGCGGCGGGA
GCGCCCCGGACGGCAGGAAGATCAAGGGGACCATCCACTGGGTGAGCGCCGACCACGCTGTCGACGCCGAAGTGCGCCTG
TACGACCGCCTGTTCAGCACACCGAACCCTGGAGGGAAGAACGAGCCGGACTACCGCAGCTCGATCAACCCGAAATCGAT
CGAGGTCCTCTCCGGCTGCAAGCTGGAGCCTTCGCTCGCCGGCGCCACCCTGGAGAACCGCTACCAGTTCGAGAGGCTCG
GCTACTTCTGTCTGGACTCCAAGGATTCCAAACCGGAGGCGCTGGTGTTCAACCGCACGGCCACGCTGCGCGACTCGTGG
AGCGAGCAGAAGAAGTAG

Upstream 100 bases:

>100_bases
AGAAGGAGAGCGTGGAGACAAGGCAGCGCTCTGCGACATGGGCGCGCATCATGAAAAACCAATACACTTCGCGCCGCGAT
TTTGGCGCAAAGGAACCGAT

Downstream 100 bases:

>100_bases
GAGAAGCGCCCTCACCCCGGCCCTCTCCCACCTCCGGACCGTAGCCTACGGTGGGCGAAGGCCCAGAGGGAGAGGGAGAA
TGGACAGGGAACAGGCTCGA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MTDTKTAEASAPEKAANFIRNIVTDDLKNGKHTGIVTRFPPEPNGYLHIGHAKSICLNFGLALDFGGRCHLRFDDTNPTK
EDIEYEDSIKENVKWLGFDWGQHMYYASNYFEQFYNYAVLLIEKGLAYVDSLSADEMRALRGTLNEPGKESPYRSRGVEE
NLDLFRRMRAGEFEEGSNVLRLKIDMASPNINLRDPVIYRIRKVEHHRTGDAWCIYPMYDYAHCISDAIEGITHSVCTLE
FEDHRPLYDWVLDQLPVKCHPQQIEFARLNLSYTVMSKRKLLELVQEKLVDGWDDPRMPTLVGLRRRGFTPQSIVNFCET
IGVGKSDSFIDMSILEESVREDLNVRAPRAMSVLRPLKLVIEGYPEGESEEFEAANHPNDPEMGTRKVPFSKTVYIERDD
FQEEPAKGFFRLAPGREVRLRYAYIIRCESVVKDENGEIVEVRCSYDTGSRGGSAPDGRKIKGTIHWVSADHAVDAEVRL
YDRLFSTPNPGGKNEPDYRSSINPKSIEVLSGCKLEPSLAGATLENRYQFERLGYFCLDSKDSKPEALVFNRTATLRDSW
SEQKK

Sequences:

>Translated_565_residues
MTDTKTAEASAPEKAANFIRNIVTDDLKNGKHTGIVTRFPPEPNGYLHIGHAKSICLNFGLALDFGGRCHLRFDDTNPTK
EDIEYEDSIKENVKWLGFDWGQHMYYASNYFEQFYNYAVLLIEKGLAYVDSLSADEMRALRGTLNEPGKESPYRSRGVEE
NLDLFRRMRAGEFEEGSNVLRLKIDMASPNINLRDPVIYRIRKVEHHRTGDAWCIYPMYDYAHCISDAIEGITHSVCTLE
FEDHRPLYDWVLDQLPVKCHPQQIEFARLNLSYTVMSKRKLLELVQEKLVDGWDDPRMPTLVGLRRRGFTPQSIVNFCET
IGVGKSDSFIDMSILEESVREDLNVRAPRAMSVLRPLKLVIEGYPEGESEEFEAANHPNDPEMGTRKVPFSKTVYIERDD
FQEEPAKGFFRLAPGREVRLRYAYIIRCESVVKDENGEIVEVRCSYDTGSRGGSAPDGRKIKGTIHWVSADHAVDAEVRL
YDRLFSTPNPGGKNEPDYRSSINPKSIEVLSGCKLEPSLAGATLENRYQFERLGYFCLDSKDSKPEALVFNRTATLRDSW
SEQKK
>Mature_564_residues
TDTKTAEASAPEKAANFIRNIVTDDLKNGKHTGIVTRFPPEPNGYLHIGHAKSICLNFGLALDFGGRCHLRFDDTNPTKE
DIEYEDSIKENVKWLGFDWGQHMYYASNYFEQFYNYAVLLIEKGLAYVDSLSADEMRALRGTLNEPGKESPYRSRGVEEN
LDLFRRMRAGEFEEGSNVLRLKIDMASPNINLRDPVIYRIRKVEHHRTGDAWCIYPMYDYAHCISDAIEGITHSVCTLEF
EDHRPLYDWVLDQLPVKCHPQQIEFARLNLSYTVMSKRKLLELVQEKLVDGWDDPRMPTLVGLRRRGFTPQSIVNFCETI
GVGKSDSFIDMSILEESVREDLNVRAPRAMSVLRPLKLVIEGYPEGESEEFEAANHPNDPEMGTRKVPFSKTVYIERDDF
QEEPAKGFFRLAPGREVRLRYAYIIRCESVVKDENGEIVEVRCSYDTGSRGGSAPDGRKIKGTIHWVSADHAVDAEVRLY
DRLFSTPNPGGKNEPDYRSSINPKSIEVLSGCKLEPSLAGATLENRYQFERLGYFCLDSKDSKPEALVFNRTATLRDSWS
EQKK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=529, Percent_Identity=47.2589792060491, Blast_Score=447, Evalue=1e-125,
Organism=Homo sapiens, GI62241042, Length=542, Percent_Identity=33.5793357933579, Blast_Score=275, Evalue=1e-73,
Organism=Escherichia coli, GI1786895, Length=554, Percent_Identity=60.8303249097473, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=308, Percent_Identity=23.7012987012987, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=541, Percent_Identity=43.6229205175601, Blast_Score=434, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17511007, Length=518, Percent_Identity=31.8532818532818, Blast_Score=234, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6324742, Length=566, Percent_Identity=40.4593639575972, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321192, Length=527, Percent_Identity=35.1043643263757, Blast_Score=292, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6324540, Length=302, Percent_Identity=22.5165562913907, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17864488, Length=526, Percent_Identity=43.7262357414449, Blast_Score=445, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24649466, Length=422, Percent_Identity=36.9668246445498, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24665321, Length=318, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64578; Mature: 64446

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTKTAEASAPEKAANFIRNIVTDDLKNGKHTGIVTRFPPEPNGYLHIGHAKSICLNFG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEHHHCC
LALDFGGRCHLRFDDTNPTKEDIEYEDSIKENVKWLGFDWGQHMYYASNYFEQFYNYAVL
EEEECCCEEEEEECCCCCCHHHCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHEEE
LIEKGLAYVDSLSADEMRALRGTLNEPGKESPYRSRGVEENLDLFRRMRAGEFEEGSNVL
EHHHCHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCEE
RLKIDMASPNINLRDPVIYRIRKVEHHRTGDAWCIYPMYDYAHCISDAIEGITHSVCTLE
EEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEEE
FEDHRPLYDWVLDQLPVKCHPQQIEFARLNLSYTVMSKRKLLELVQEKLVDGWDDPRMPT
ECCCCCHHHHHHHCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCH
LVGLRRRGFTPQSIVNFCETIGVGKSDSFIDMSILEESVREDLNVRAPRAMSVLRPLKLV
HHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
IEGYPEGESEEFEAANHPNDPEMGTRKVPFSKTVYIERDDFQEEPAKGFFRLAPGREVRL
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEE
RYAYIIRCESVVKDENGEIVEVRCSYDTGSRGGSAPDGRKIKGTIHWVSADHAVDAEVRL
EEEEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHH
YDRLFSTPNPGGKNEPDYRSSINPKSIEVLSGCKLEPSLAGATLENRYQFERLGYFCLDS
HHHHHCCCCCCCCCCCCHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECC
KDSKPEALVFNRTATLRDSWSEQKK
CCCCCCEEEEECCHHHHHCHHHCCC
>Mature Secondary Structure 
TDTKTAEASAPEKAANFIRNIVTDDLKNGKHTGIVTRFPPEPNGYLHIGHAKSICLNFG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEHHHCC
LALDFGGRCHLRFDDTNPTKEDIEYEDSIKENVKWLGFDWGQHMYYASNYFEQFYNYAVL
EEEECCCEEEEEECCCCCCHHHCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHEEE
LIEKGLAYVDSLSADEMRALRGTLNEPGKESPYRSRGVEENLDLFRRMRAGEFEEGSNVL
EHHHCHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCEE
RLKIDMASPNINLRDPVIYRIRKVEHHRTGDAWCIYPMYDYAHCISDAIEGITHSVCTLE
EEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEEE
FEDHRPLYDWVLDQLPVKCHPQQIEFARLNLSYTVMSKRKLLELVQEKLVDGWDDPRMPT
ECCCCCHHHHHHHCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCH
LVGLRRRGFTPQSIVNFCETIGVGKSDSFIDMSILEESVREDLNVRAPRAMSVLRPLKLV
HHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
IEGYPEGESEEFEAANHPNDPEMGTRKVPFSKTVYIERDDFQEEPAKGFFRLAPGREVRL
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEE
RYAYIIRCESVVKDENGEIVEVRCSYDTGSRGGSAPDGRKIKGTIHWVSADHAVDAEVRL
EEEEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHH
YDRLFSTPNPGGKNEPDYRSSINPKSIEVLSGCKLEPSLAGATLENRYQFERLGYFCLDS
HHHHHCCCCCCCCCCCCHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECC
KDSKPEALVFNRTATLRDSWSEQKK
CCCCCCEEEEECCHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]