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The map label for this gene is 197120087

Identifier: 197120087

GI number: 197120087

Start: 4253340

End: 4254356

Strand: Direct

Name: 197120087

Synonym: Gbem_3726

Alternate gene names: NA

Gene position: 4253340-4254356 (Clockwise)

Preceding gene: 197120086

Following gene: 197120088

Centisome position: 92.16

GC content: 65.19

Gene sequence:

>1017_bases
ATGAAACTTTCCTTCGCACCGAGACAGCCGATCTACATCATCGCCGAGATCGGCGGCAACTTCACCACCTTCGAGGAGGC
AAAGGCGCTGGTCGATGCCGCCGCCTCCTGCGGGGTGGACGCGGTCAAGCTGCAGACCTACCGCGCCGAGACCGTCTCCA
GCAAAAGCGCCATCTTCGACATGGAGAACACCGGCATCGCCTCCCAGTTCGAACTCTTCCAAAAGTACGAGATCGACGAG
GAGCTGCACCGGCAGGTCTTCGACTACATCCGGGCGAAAGGGCTCGACTGGTTCTCCACCCCCTCGCACGAAGCCGACGT
CGACCTGCTGGACCGGCTCGGGGTAAGCGCCTACAAGATCGGCTCCGACGACGCGGTCAACATCCCGTTCCTCAGGTACG
TCGCCGCGAAGGGGAAGCCGGTCCTCCTCGCCACCGGCATGTGCACCATGCAGGAGGTGCGCGAGTCGGTGGACGTGATC
CTCGGCGCCGGCAACCTCGAGCTCATCCTCCTGCACGCGGTGACGAGCTACCCCACCCATCCGGAGCACGTGAACCTCCT
TGCCATGCAGGCTCTGGCGCGCGAATTCAACCTCCCGGTCGGCTACTCGGACCACACCATCGGGACCGTGGCCTGTCTTG
GCGCCGCAGCGCTCGGCGCCGCGGTCCTCGAGAAGCACTTCACCACGGACAAGAACGCCGAGGGGCCGGACCACATCCTC
TCCGCCGACCCGGCCGAGATGAGGACCATCGTGGAACAGGTGAGGACCCTGGAGGCCATGATGGGAAGCGGCGTCAAGAT
GCCGGCCGCCTCAGAGAAGACAACGCGGATTAACAACAGAAAGAGCATCGTCGCGGCGCGGGCGCTCCCTGCCGGACACC
GGCTGACGGCGGAGGACATCGCCGTGAAGCGCCCCGGCTTCGGCATCCCCCCCCGCTTCAGGGAGGAGCTCCCGGGAAGC
GTCTTGAACGAGCCCGTGGAGCAGGACGAAGTGATCCCCTGGAGCAAGCTGCGATGA

Upstream 100 bases:

>100_bases
ACGAGGTCCCCGACACCGTCGCCGACATTTCGGCCATCACCAGGGCGCTCGGCTGGCTTCCCAGGCGCACCCTGGAGCAA
TTCCTGAAATCGGAGCTCGC

Downstream 100 bases:

>100_bases
ACGGCGCGCAGGTGGGAATCATCATCCAGGCCCGGATGGGATCGACGAGGCTCCCGGAGAAGGTGCTGAAGCCGATCGGG
AACAGGGTGCTTTTGGGGCA

Product: N-acetylneuraminic acid synthase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKLSFAPRQPIYIIAEIGGNFTTFEEAKALVDAAASCGVDAVKLQTYRAETVSSKSAIFDMENTGIASQFELFQKYEIDE
ELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDAVNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVI
LGAGNLELILLHAVTSYPTHPEHVNLLAMQALAREFNLPVGYSDHTIGTVACLGAAALGAAVLEKHFTTDKNAEGPDHIL
SADPAEMRTIVEQVRTLEAMMGSGVKMPAASEKTTRINNRKSIVAARALPAGHRLTAEDIAVKRPGFGIPPRFREELPGS
VLNEPVEQDEVIPWSKLR

Sequences:

>Translated_338_residues
MKLSFAPRQPIYIIAEIGGNFTTFEEAKALVDAAASCGVDAVKLQTYRAETVSSKSAIFDMENTGIASQFELFQKYEIDE
ELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDAVNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVI
LGAGNLELILLHAVTSYPTHPEHVNLLAMQALAREFNLPVGYSDHTIGTVACLGAAALGAAVLEKHFTTDKNAEGPDHIL
SADPAEMRTIVEQVRTLEAMMGSGVKMPAASEKTTRINNRKSIVAARALPAGHRLTAEDIAVKRPGFGIPPRFREELPGS
VLNEPVEQDEVIPWSKLR
>Mature_338_residues
MKLSFAPRQPIYIIAEIGGNFTTFEEAKALVDAAASCGVDAVKLQTYRAETVSSKSAIFDMENTGIASQFELFQKYEIDE
ELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDAVNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVI
LGAGNLELILLHAVTSYPTHPEHVNLLAMQALAREFNLPVGYSDHTIGTVACLGAAALGAAVLEKHFTTDKNAEGPDHIL
SADPAEMRTIVEQVRTLEAMMGSGVKMPAASEKTTRINNRKSIVAARALPAGHRLTAEDIAVKRPGFGIPPRFREELPGS
VLNEPVEQDEVIPWSKLR

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=332, Percent_Identity=31.9277108433735, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21357081, Length=357, Percent_Identity=30.812324929972, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 36890; Mature: 36890

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSFAPRQPIYIIAEIGGNFTTFEEAKALVDAAASCGVDAVKLQTYRAETVSSKSAIFD
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCHHEEE
MENTGIASQFELFQKYEIDEELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKI
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEC
GSDDAVNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVILGAGNLELILLHAVTSYPTH
CCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHEEECCCCCEEEEEEEHHCCCCC
PEHVNLLAMQALAREFNLPVGYSDHTIGTVACLGAAALGAAVLEKHFTTDKNAEGPDHIL
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHC
SADPAEMRTIVEQVRTLEAMMGSGVKMPAASEKTTRINNRKSIVAARALPAGHRLTAEDI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHEEHHHCCCCCCCCCHHHH
AVKRPGFGIPPRFREELPGSVLNEPVEQDEVIPWSKLR
EEECCCCCCCCHHHHHCCHHHHCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MKLSFAPRQPIYIIAEIGGNFTTFEEAKALVDAAASCGVDAVKLQTYRAETVSSKSAIFD
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCHHEEE
MENTGIASQFELFQKYEIDEELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKI
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEC
GSDDAVNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVILGAGNLELILLHAVTSYPTH
CCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHEEECCCCCEEEEEEEHHCCCCC
PEHVNLLAMQALAREFNLPVGYSDHTIGTVACLGAAALGAAVLEKHFTTDKNAEGPDHIL
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHC
SADPAEMRTIVEQVRTLEAMMGSGVKMPAASEKTTRINNRKSIVAARALPAGHRLTAEDI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHEEHHHCCCCCCCCCHHHH
AVKRPGFGIPPRFREELPGSVLNEPVEQDEVIPWSKLR
EEECCCCCCCCHHHHHCCHHHHCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]