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The map label for this gene is cheW-3 [H]

Identifier: 197119526

GI number: 197119526

Start: 3640958

End: 3641452

Strand: Direct

Name: cheW-3 [H]

Synonym: Gbem_3155

Alternate gene names: 197119526

Gene position: 3640958-3641452 (Clockwise)

Preceding gene: 197119518

Following gene: 197119532

Centisome position: 78.89

GC content: 59.39

Gene sequence:

>495_bases
ATGGCAGTCGAGACTATCACGGAGACTACACAGTATCTGACGTTCAAACTGGAGGACGAGCTCTTCGCACTCGACATCGG
GAAGGTGCGTGAAGTGCTCGATTTCACCACCATCACCAAGGTGCCCCAGACGCCGGACTACATGCGCGGTGTCATCAACC
TGCGCGGCAGCGTGGTGCCGGTAGTGGACCTGCGCTTGAAGTTCGGGATGGTGATGGCGGAGCAGACGGTAAACACCTGC
GTCATCATCGTCGAGGTCGAGCTGGAAGGGGAGCGTGTGGTGATGGGCGCCATGGCAGATGCGGTCCAGGAAGTGCTCGA
TCTCGAGCCGGACCAGATCGAGCCGCCGCCGCGCATCGGCACGAAGCTCAATACCGAGTTCATCAAGGGGATGGGGAAAC
ACAACGACCAGTTCATCATCATCCTGGACATCGACAAGGTGTTCACCTCCAGCGAGCTGGAACTGGCGCGCGAAGTGGAA
GGCGCCGCAGCTTAA

Upstream 100 bases:

>100_bases
TTTTTTCTGTATCTGTCGATACTTTATACAGAAAAGAACCACCGGGCTGTCGACCGGCCCCAAGTCCTATAGCATCAATC
CCTGAGAGAGGAGAACAACT

Downstream 100 bases:

>100_bases
GCGCCAAACACAGCGTCAGCAACCAAAAGGCAGCCGGGTCATGCACCCAGGCTGCCTTTTTTGCGTCTGCCTGCCTCACT
GGTAAAGGGGGCGGTGCTAA

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MAVETITETTQYLTFKLEDELFALDIGKVREVLDFTTITKVPQTPDYMRGVINLRGSVVPVVDLRLKFGMVMAEQTVNTC
VIIVEVELEGERVVMGAMADAVQEVLDLEPDQIEPPPRIGTKLNTEFIKGMGKHNDQFIIILDIDKVFTSSELELAREVE
GAAA

Sequences:

>Translated_164_residues
MAVETITETTQYLTFKLEDELFALDIGKVREVLDFTTITKVPQTPDYMRGVINLRGSVVPVVDLRLKFGMVMAEQTVNTC
VIIVEVELEGERVVMGAMADAVQEVLDLEPDQIEPPPRIGTKLNTEFIKGMGKHNDQFIIILDIDKVFTSSELELAREVE
GAAA
>Mature_163_residues
AVETITETTQYLTFKLEDELFALDIGKVREVLDFTTITKVPQTPDYMRGVINLRGSVVPVVDLRLKFGMVMAEQTVNTCV
IIVEVELEGERVVMGAMADAVQEVLDLEPDQIEPPPRIGTKLNTEFIKGMGKHNDQFIIILDIDKVFTSSELELAREVEG
AAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=145, Percent_Identity=40, Blast_Score=117, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18256; Mature: 18125

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVETITETTQYLTFKLEDELFALDIGKVREVLDFTTITKVPQTPDYMRGVINLRGSVVP
CCCCHHHCCCEEEEEEECCCEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEE
VVDLRLKFGMVMAEQTVNTCVIIVEVELEGERVVMGAMADAVQEVLDLEPDQIEPPPRIG
EEEHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCC
TKLNTEFIKGMGKHNDQFIIILDIDKVFTSSELELAREVEGAAA
CCCCHHHHHCCCCCCCCEEEEEECCHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVETITETTQYLTFKLEDELFALDIGKVREVLDFTTITKVPQTPDYMRGVINLRGSVVP
CCCHHHCCCEEEEEEECCCEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEE
VVDLRLKFGMVMAEQTVNTCVIIVEVELEGERVVMGAMADAVQEVLDLEPDQIEPPPRIG
EEEHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCC
TKLNTEFIKGMGKHNDQFIIILDIDKVFTSSELELAREVEGAAA
CCCCHHHHHCCCCCCCCEEEEEECCHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]