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The map label for this gene is yciR [C]

Identifier: 197119194

GI number: 197119194

Start: 3247293

End: 3248864

Strand: Reverse

Name: yciR [C]

Synonym: Gbem_2821

Alternate gene names: 197119194

Gene position: 3248864-3247293 (Counterclockwise)

Preceding gene: 197119195

Following gene: 197119193

Centisome position: 70.4

GC content: 61.07

Gene sequence:

>1572_bases
ATGGGTCGCGTCGGAATACGCAGACTTTTCAGCTGGATAGGGGGGCTCTCCCCCGCCGCCATCAGCTCCATCTTCGCCTT
CAGCAGCCTCTCTTGGCTTCTTCTTGCCCACCTTCTCTTCCGTAGCATATTTGTAGACCGCGAACTCACCTACCTCGCCC
TTAGCATCCTCGAGCTTTTCGGGGTCGCCACCATGACCGTCATCGTCTATCTGCTCAGCGACAAGAGCGAAGCAAGGCAT
CGGGCCATCGAGTCGAGCATCCGCGAGCAGGCCATACGCGACGGGCTCACCGGGCTCTACAACCGGCAGGCTTTCGACGA
TTTCCTGGCGCAGTCCATCGAATACGTCAAACGCCGCAGGGAGTCTGTCGCCCTGTTGTTTCTCGACCTGGACCGGTTCA
AATTCGTCAACGACAGGCGTGGGCATTTCGTGGGAGACGCGGTCCTAATCGAGACAGCGCGACGGCTCACCGACTGCGCC
AAACGCGGAGAAGACCTGGTGGCCCGGGTGGGGGGGGACGAGTTCGCCATGCTGCTGCGCCACCCCGATATGCCGGACGG
GCCGGGGGTTGTCGCCAGGCGTGTGCTGGAGTCGTTGTCGGCGCCGGTGCAGGTGGATGGCGAGACGCTGAAGACCAGCG
TCAGCATCGGCATCGCCATGTTTCCTTCCGACGCTGACGATCCCATGCAGCTCTTCAAGATGGCCGATTTCGCCCTGAAC
CAGGCGAAGCAGCAGGGACGCGCGACCTTCTGCTTCTATGGCGGCGAATGGCGGGAAGAGCGCGACCATACCCTGCAGTT
GGAACAGGGGCTCTTGCGTGCCATCAACTACGACGAGTTGTTCCTGGTTTACCAGCCCAAGCTGGATACCTCCAACATGC
GCGTCATCGGAGTTGAGGCACTGGTGCGCTGGAAGCACCCGCACTTGGGAGTGCTCGGGCCGGCGAGCTTCGTCCCCGTG
GCCGAGAAGGCTGGCCTCATCTGGCCGCTGACCGAGTGGGTGCTGAAGAATGCCTGTTCCCAGGCGGCGCGCTGGTACCG
CAACGAGGGGCTGGACCTGAACGTCGCCGTCAACCTCTCCCCTTCCGTTTTCTCGCATCAGGACCTGGAAGAGGTGATCG
AGAAGGCGCTGAACGACAGCAAACTCCCCCCGGACCGGCTCACGCTCGAGATCACGGAGCAGTCGCTGATGATCTACGAG
ACGGAGGCGCTCGGGGTGCTGGAGCGCCTGCAGCGGATGGGAACCAACATCCAGATAGACGACTTCGGCACCGGCTACTC
GTCCCTCTCTTCTCTCAAGCACTACCACTTCCAGGCGCTCAAGATAGACAAGTCCTTCGTCAGCGACGTCGTCACCTCTT
CGGACGACGCCGCCATCGCCACCACCATCATGTTCATGTCCAAATGCCTTGACATGGAGGCCATCGCAGAAGGGGTGGAA
TCCGAGGCGCAAAAGGAATTCCTCTCCTCCATCGACTGCCGCTACATGCAGGGTTTCTATTTCTCCCGCCCCCTCGTCGC
CTCTGAAATGGCCGATTTCATCAGGCATCTCGCCGACGACAAGAAAGCTTGA

Upstream 100 bases:

>100_bases
TCCTGCTCTCCTTTGTTTCAATTTCTGCGCCGCAACGTCTTTTTCCATCCCTGCGCTATACTAGGACGGTGTTTTTTTCC
CCTGGAGCGAGGAGAAAGCT

Downstream 100 bases:

>100_bases
AATGCACATCTCCACCTATATAATAGTGAGCGTTCTCTAATTCCATTAATCACTAGAAAGGAGTCTGCTCATGGGTGACA
GACAAAAGACGGTGGGGGTG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MGRVGIRRLFSWIGGLSPAAISSIFAFSSLSWLLLAHLLFRSIFVDRELTYLALSILELFGVATMTVIVYLLSDKSEARH
RAIESSIREQAIRDGLTGLYNRQAFDDFLAQSIEYVKRRRESVALLFLDLDRFKFVNDRRGHFVGDAVLIETARRLTDCA
KRGEDLVARVGGDEFAMLLRHPDMPDGPGVVARRVLESLSAPVQVDGETLKTSVSIGIAMFPSDADDPMQLFKMADFALN
QAKQQGRATFCFYGGEWREERDHTLQLEQGLLRAINYDELFLVYQPKLDTSNMRVIGVEALVRWKHPHLGVLGPASFVPV
AEKAGLIWPLTEWVLKNACSQAARWYRNEGLDLNVAVNLSPSVFSHQDLEEVIEKALNDSKLPPDRLTLEITEQSLMIYE
TEALGVLERLQRMGTNIQIDDFGTGYSSLSSLKHYHFQALKIDKSFVSDVVTSSDDAAIATTIMFMSKCLDMEAIAEGVE
SEAQKEFLSSIDCRYMQGFYFSRPLVASEMADFIRHLADDKKA

Sequences:

>Translated_523_residues
MGRVGIRRLFSWIGGLSPAAISSIFAFSSLSWLLLAHLLFRSIFVDRELTYLALSILELFGVATMTVIVYLLSDKSEARH
RAIESSIREQAIRDGLTGLYNRQAFDDFLAQSIEYVKRRRESVALLFLDLDRFKFVNDRRGHFVGDAVLIETARRLTDCA
KRGEDLVARVGGDEFAMLLRHPDMPDGPGVVARRVLESLSAPVQVDGETLKTSVSIGIAMFPSDADDPMQLFKMADFALN
QAKQQGRATFCFYGGEWREERDHTLQLEQGLLRAINYDELFLVYQPKLDTSNMRVIGVEALVRWKHPHLGVLGPASFVPV
AEKAGLIWPLTEWVLKNACSQAARWYRNEGLDLNVAVNLSPSVFSHQDLEEVIEKALNDSKLPPDRLTLEITEQSLMIYE
TEALGVLERLQRMGTNIQIDDFGTGYSSLSSLKHYHFQALKIDKSFVSDVVTSSDDAAIATTIMFMSKCLDMEAIAEGVE
SEAQKEFLSSIDCRYMQGFYFSRPLVASEMADFIRHLADDKKA
>Mature_522_residues
GRVGIRRLFSWIGGLSPAAISSIFAFSSLSWLLLAHLLFRSIFVDRELTYLALSILELFGVATMTVIVYLLSDKSEARHR
AIESSIREQAIRDGLTGLYNRQAFDDFLAQSIEYVKRRRESVALLFLDLDRFKFVNDRRGHFVGDAVLIETARRLTDCAK
RGEDLVARVGGDEFAMLLRHPDMPDGPGVVARRVLESLSAPVQVDGETLKTSVSIGIAMFPSDADDPMQLFKMADFALNQ
AKQQGRATFCFYGGEWREERDHTLQLEQGLLRAINYDELFLVYQPKLDTSNMRVIGVEALVRWKHPHLGVLGPASFVPVA
EKAGLIWPLTEWVLKNACSQAARWYRNEGLDLNVAVNLSPSVFSHQDLEEVIEKALNDSKLPPDRLTLEITEQSLMIYET
EALGVLERLQRMGTNIQIDDFGTGYSSLSSLKHYHFQALKIDKSFVSDVVTSSDDAAIATTIMFMSKCLDMEAIAEGVES
EAQKEFLSSIDCRYMQGFYFSRPLVASEMADFIRHLADDKKA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=440, Percent_Identity=33.6363636363636, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87081921, Length=428, Percent_Identity=31.3084112149533, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI226510982, Length=444, Percent_Identity=27.027027027027, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788502, Length=247, Percent_Identity=33.1983805668016, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=33.469387755102, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=34.4, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=32.2314049586777, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=32.9317269076305, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787055, Length=270, Percent_Identity=27.4074074074074, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788849, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=25.9109311740891, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788381, Length=439, Percent_Identity=25.9681093394077, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87082096, Length=214, Percent_Identity=28.5046728971963, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786584, Length=219, Percent_Identity=30.5936073059361, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081881, Length=191, Percent_Identity=34.0314136125654, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=33.7423312883436, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=35.7142857142857, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082007, Length=218, Percent_Identity=31.1926605504587, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=204, Percent_Identity=26.9607843137255, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=32.5301204819277, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787802, Length=206, Percent_Identity=30.5825242718447, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 58835; Mature: 58704

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVGIRRLFSWIGGLSPAAISSIFAFSSLSWLLLAHLLFRSIFVDRELTYLALSILELF
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GVATMTVIVYLLSDKSEARHRAIESSIREQAIRDGLTGLYNRQAFDDFLAQSIEYVKRRR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESVALLFLDLDRFKFVNDRRGHFVGDAVLIETARRLTDCAKRGEDLVARVGGDEFAMLLR
HCEEEEEEEHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHC
HPDMPDGPGVVARRVLESLSAPVQVDGETLKTSVSIGIAMFPSDADDPMQLFKMADFALN
CCCCCCCCCHHHHHHHHHCCCCEEECCHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHH
QAKQQGRATFCFYGGEWREERDHTLQLEQGLLRAINYDELFLVYQPKLDTSNMRVIGVEA
HHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHH
LVRWKHPHLGVLGPASFVPVAEKAGLIWPLTEWVLKNACSQAARWYRNEGLDLNVAVNLS
HHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
PSVFSHQDLEEVIEKALNDSKLPPDRLTLEITEQSLMIYETEALGVLERLQRMGTNIQID
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHCCCEEEE
DFGTGYSSLSSLKHYHFQALKIDKSFVSDVVTSSDDAAIATTIMFMSKCLDMEAIAEGVE
CCCCCHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
SEAQKEFLSSIDCRYMQGFYFSRPLVASEMADFIRHLADDKKA
HHHHHHHHHHHCHHHHHCHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GRVGIRRLFSWIGGLSPAAISSIFAFSSLSWLLLAHLLFRSIFVDRELTYLALSILELF
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GVATMTVIVYLLSDKSEARHRAIESSIREQAIRDGLTGLYNRQAFDDFLAQSIEYVKRRR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESVALLFLDLDRFKFVNDRRGHFVGDAVLIETARRLTDCAKRGEDLVARVGGDEFAMLLR
HCEEEEEEEHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHC
HPDMPDGPGVVARRVLESLSAPVQVDGETLKTSVSIGIAMFPSDADDPMQLFKMADFALN
CCCCCCCCCHHHHHHHHHCCCCEEECCHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHH
QAKQQGRATFCFYGGEWREERDHTLQLEQGLLRAINYDELFLVYQPKLDTSNMRVIGVEA
HHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHH
LVRWKHPHLGVLGPASFVPVAEKAGLIWPLTEWVLKNACSQAARWYRNEGLDLNVAVNLS
HHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
PSVFSHQDLEEVIEKALNDSKLPPDRLTLEITEQSLMIYETEALGVLERLQRMGTNIQID
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHCCCEEEE
DFGTGYSSLSSLKHYHFQALKIDKSFVSDVVTSSDDAAIATTIMFMSKCLDMEAIAEGVE
CCCCCHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
SEAQKEFLSSIDCRYMQGFYFSRPLVASEMADFIRHLADDKKA
HHHHHHHHHHHCHHHHHCHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]