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The map label for this gene is atoS [H]

Identifier: 197119034

GI number: 197119034

Start: 3074940

End: 3077429

Strand: Direct

Name: atoS [H]

Synonym: Gbem_2657

Alternate gene names: 197119034

Gene position: 3074940-3077429 (Clockwise)

Preceding gene: 197119027

Following gene: 197119035

Centisome position: 66.63

GC content: 61.77

Gene sequence:

>2490_bases
TTGCCACGCTTCACGCTTTTCAAAAAGATCCTGGTCATCACGCTGCTGCTCTCCCTGCTGCCGCTGTTCGTCTCCTCCGC
CATCCTCCTGATGAACCTGCAGTCGATCAGCACCAAGTTGACCGACGAGATCTCCCGTTCGGACGACCGGCAGGCGACCC
AGTCGCTGCAGATGAAGGCGCGGGACCTGGCCGAAAACATACGCGATTTCCTGCACCAGTGCGAAAGCGACCTGCTCTTT
CTTTCGCGCTCCCGCCTGGACCGCTCGACGCTGCTCGACTTCTACCAGACCCGCTTAAGCGAGGTGTGGCAGCGCGGAGC
AAGCGCCACCGCGACCCAGGGAACCCACGAGTTCCGCCCCATATACCGCTCCATAGCCATCATCGACCGCAACGGTATGG
AACAATCGGCGATCCGAAACGGCCAGTTGGTCCCCAAGGAGCAACTGCGCAACGTGGCGGACCCCGCCAACACCGAGTTC
AAGAGCGAGGAGTACTTCCGGCGCGTGCGGGCACTAAAGCCCGGCGAGATCTACGTCTCGCACCTCACCGGTTTTCACGT
CTCCAAGCAGGAGCAACTGGCCGGGGCCAAGGACCCGGAAAGCGCCTACGACGGTAAAGGCTACCAGGGGGGCATCCGGT
TCGGCTCGCCCATCTACGACTCCAAAGGGAAGTTCTCCGGCATGGTGCTGCTGACCTTGGACCATCAGCACCTCATGGAA
TTCACCCAGCACATCGACCCGGGCAAGGGTTTCGGCACCCTCTTCCCCTCCTACCAAAGCGGCAACTACGCCTTTCTCTT
CGACGACGAGGGGTGGATCATCACCCATCCCAAGTATTGGGACATCCGGGGGGTGGACCAGACGGGCAGACTTGTCCCGC
CTTACACGGCGGATTCGAAACAGGACGACGTCGACAGCGGCCGCATCCCCTTCAACCTAGACCACGCCGGCTTCATCCAC
AAAAGCTACCCCACGGTCTCCGCCGCGGTCCGCAACCGCCAGGAAGGGTTCGTCGACATCACCAACGTCGGGGGCGCCAA
GAAGATCATGGCCTACGCCCCCATCTTCTACGACACCGGGGACTACGCGAGGCACGGCGTCTTCGGCGGTGTGACCATCG
GGTTCCAGGTGGACCAGTTTCACGAAGCGTCCCACAAGGGGAGCCGACTGATCGATAGGCAACTGGGCGAACACCGCCGA
ACCAGCGCCCTCATCATCCTGGCCACCGCCCTGGTCTCGGCGCTCTCTGCCTGGCTCTTGTCCCGCGGCATCAGCATCCC
GCTTCGGCAGCTAACCGAAAGCGCCGGTAAGCTTGCCGCCGGCGACAGCCACGTCAGGGTGGCGGTGAATTCCAGCGACG
AAATAGGTGTCCTCGCCAATACCTTCAACTATATGGCGGACGAATTGGACTTGAGGAAGCAGAGCATACTCTCCACGCTC
GACGAACTGCGCAAGTCGCGGCTGGAAATCCTCGACGAGCGCAACTTCAAGGAGAGCGTGCTGGAAAGTATCTCCAGCGG
CATCGTCACCTTCTCCCCACAGGGGCGCCTCACCTCGATCAACCGAACCGGCCGCCTGTTCCTCGGAGAGGGGCTCGCAG
CAGAGACGCATTACACCGAGGTCTTCAAGGGGTGGGGCGTCCTGAACGAGCGGATCTCGCAGGTCCTTTCGAAACAGTCG
GGGTACGGGCGCGAGACCTTCCGCTTCGATCACGGCCCCGGCAAGACCCATTTCGACGTGGGGTTCTTCCCCATCGGCGC
CGACGCGGAGCAGGGGCTCACCGTAACGCTGAGAAACGAGACGCAGCGGGAGAACCTGCAAGAGGAGATGATGCGCCTGG
ACCGCCTCGCCTCGCTGGGAAAACTTTCCGCAGGCATCGCCCACGAGGTAAGAAACCCGCTCACTGGCATCTCGTTGCTT
TTGGACGATCTGCACGACCAGGCAAGCTCCGGCCCGGAGGACCGGGACCTGATCAAGAAGGCCCTGGCGGAAATCGAGCG
GGTGGAAAAACTGATCAACGCGCTTTTGAACTACTCCTCGCCGGTACGCGCCGACTTCAGGGAATGTGACCTGAACCGCC
TGGTCTGCGACACGGTCCTTTTGATGCGGCGCCAGTGCGAGCGGCAGAAGGTGCAGTTGAACCTGACCGAGGGAGAAGTC
CCCCCGCTGCGGCTGGACCCGGAAAAGATAAAGCAGGCCGTGCTCAACATCATCAAGAACGCCCAGGAAGCGCTCCCTGA
AGGAGGGCGGATCGAGGTAGTCACCTCGGTCCAGGACGGGTACGCGGTGATCGGCATCGGCGACGACGGACCAGGCATCG
CCTCTCACGACCTGCCGCTCATATTCGAGCCTTTCTTCACCAGAAAAGGGGCCGGCACCGGCCTCGGACTCTCCATTACC
CAGAGGATAGTCGAGGAACATCATGGGAAGGTCCGCGTGGAAACCGCACCGGGAGGAGGGACCAGGTTCACCATCGAACT
TCCTTTATAG

Upstream 100 bases:

>100_bases
ACATTAAAACGAAAACTGTTCTGAAATCCCCTTTTGTGCTACTCTGCCAGCCGACTTGAAAGCCAGTCCCGCGGCATCAC
GAGTTTTTTGGAGAGTCTCC

Downstream 100 bases:

>100_bases
TCCCAGATTAGTGACCATCTTCCGCCAGTCCCCTCTCCCAGAGGGAGAGGGGACTGTGGACGGAGGGGGAGTAACCAACC
AGCAGCAGCGGGAACGGGAA

Product: HAMP domain-containing sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 829; Mature: 828

Protein sequence:

>829_residues
MPRFTLFKKILVITLLLSLLPLFVSSAILLMNLQSISTKLTDEISRSDDRQATQSLQMKARDLAENIRDFLHQCESDLLF
LSRSRLDRSTLLDFYQTRLSEVWQRGASATATQGTHEFRPIYRSIAIIDRNGMEQSAIRNGQLVPKEQLRNVADPANTEF
KSEEYFRRVRALKPGEIYVSHLTGFHVSKQEQLAGAKDPESAYDGKGYQGGIRFGSPIYDSKGKFSGMVLLTLDHQHLME
FTQHIDPGKGFGTLFPSYQSGNYAFLFDDEGWIITHPKYWDIRGVDQTGRLVPPYTADSKQDDVDSGRIPFNLDHAGFIH
KSYPTVSAAVRNRQEGFVDITNVGGAKKIMAYAPIFYDTGDYARHGVFGGVTIGFQVDQFHEASHKGSRLIDRQLGEHRR
TSALIILATALVSALSAWLLSRGISIPLRQLTESAGKLAAGDSHVRVAVNSSDEIGVLANTFNYMADELDLRKQSILSTL
DELRKSRLEILDERNFKESVLESISSGIVTFSPQGRLTSINRTGRLFLGEGLAAETHYTEVFKGWGVLNERISQVLSKQS
GYGRETFRFDHGPGKTHFDVGFFPIGADAEQGLTVTLRNETQRENLQEEMMRLDRLASLGKLSAGIAHEVRNPLTGISLL
LDDLHDQASSGPEDRDLIKKALAEIERVEKLINALLNYSSPVRADFRECDLNRLVCDTVLLMRRQCERQKVQLNLTEGEV
PPLRLDPEKIKQAVLNIIKNAQEALPEGGRIEVVTSVQDGYAVIGIGDDGPGIASHDLPLIFEPFFTRKGAGTGLGLSIT
QRIVEEHHGKVRVETAPGGGTRFTIELPL

Sequences:

>Translated_829_residues
MPRFTLFKKILVITLLLSLLPLFVSSAILLMNLQSISTKLTDEISRSDDRQATQSLQMKARDLAENIRDFLHQCESDLLF
LSRSRLDRSTLLDFYQTRLSEVWQRGASATATQGTHEFRPIYRSIAIIDRNGMEQSAIRNGQLVPKEQLRNVADPANTEF
KSEEYFRRVRALKPGEIYVSHLTGFHVSKQEQLAGAKDPESAYDGKGYQGGIRFGSPIYDSKGKFSGMVLLTLDHQHLME
FTQHIDPGKGFGTLFPSYQSGNYAFLFDDEGWIITHPKYWDIRGVDQTGRLVPPYTADSKQDDVDSGRIPFNLDHAGFIH
KSYPTVSAAVRNRQEGFVDITNVGGAKKIMAYAPIFYDTGDYARHGVFGGVTIGFQVDQFHEASHKGSRLIDRQLGEHRR
TSALIILATALVSALSAWLLSRGISIPLRQLTESAGKLAAGDSHVRVAVNSSDEIGVLANTFNYMADELDLRKQSILSTL
DELRKSRLEILDERNFKESVLESISSGIVTFSPQGRLTSINRTGRLFLGEGLAAETHYTEVFKGWGVLNERISQVLSKQS
GYGRETFRFDHGPGKTHFDVGFFPIGADAEQGLTVTLRNETQRENLQEEMMRLDRLASLGKLSAGIAHEVRNPLTGISLL
LDDLHDQASSGPEDRDLIKKALAEIERVEKLINALLNYSSPVRADFRECDLNRLVCDTVLLMRRQCERQKVQLNLTEGEV
PPLRLDPEKIKQAVLNIIKNAQEALPEGGRIEVVTSVQDGYAVIGIGDDGPGIASHDLPLIFEPFFTRKGAGTGLGLSIT
QRIVEEHHGKVRVETAPGGGTRFTIELPL
>Mature_828_residues
PRFTLFKKILVITLLLSLLPLFVSSAILLMNLQSISTKLTDEISRSDDRQATQSLQMKARDLAENIRDFLHQCESDLLFL
SRSRLDRSTLLDFYQTRLSEVWQRGASATATQGTHEFRPIYRSIAIIDRNGMEQSAIRNGQLVPKEQLRNVADPANTEFK
SEEYFRRVRALKPGEIYVSHLTGFHVSKQEQLAGAKDPESAYDGKGYQGGIRFGSPIYDSKGKFSGMVLLTLDHQHLMEF
TQHIDPGKGFGTLFPSYQSGNYAFLFDDEGWIITHPKYWDIRGVDQTGRLVPPYTADSKQDDVDSGRIPFNLDHAGFIHK
SYPTVSAAVRNRQEGFVDITNVGGAKKIMAYAPIFYDTGDYARHGVFGGVTIGFQVDQFHEASHKGSRLIDRQLGEHRRT
SALIILATALVSALSAWLLSRGISIPLRQLTESAGKLAAGDSHVRVAVNSSDEIGVLANTFNYMADELDLRKQSILSTLD
ELRKSRLEILDERNFKESVLESISSGIVTFSPQGRLTSINRTGRLFLGEGLAAETHYTEVFKGWGVLNERISQVLSKQSG
YGRETFRFDHGPGKTHFDVGFFPIGADAEQGLTVTLRNETQRENLQEEMMRLDRLASLGKLSAGIAHEVRNPLTGISLLL
DDLHDQASSGPEDRDLIKKALAEIERVEKLINALLNYSSPVRADFRECDLNRLVCDTVLLMRRQCERQKVQLNLTEGEVP
PLRLDPEKIKQAVLNIIKNAQEALPEGGRIEVVTSVQDGYAVIGIGDDGPGIASHDLPLIFEPFFTRKGAGTGLGLSITQ
RIVEEHHGKVRVETAPGGGTRFTIELPL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=360, Percent_Identity=31.3888888888889, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=35.9649122807018, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=31.1688311688312, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=29.8755186721992, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=31.4553990610329, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=29.0748898678414, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=26.9058295964126, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=280, Percent_Identity=26.4285714285714, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790567, Length=350, Percent_Identity=26.8571428571429, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=218, Percent_Identity=28.8990825688073, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=221, Percent_Identity=26.6968325791855, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788393, Length=220, Percent_Identity=25.4545454545455, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=29.5154185022026, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=214, Percent_Identity=26.6355140186916, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92325; Mature: 92194

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFTLFKKILVITLLLSLLPLFVSSAILLMNLQSISTKLTDEISRSDDRQATQSLQMKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RDLAENIRDFLHQCESDLLFLSRSRLDRSTLLDFYQTRLSEVWQRGASATATQGTHEFRP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IYRSIAIIDRNGMEQSAIRNGQLVPKEQLRNVADPANTEFKSEEYFRRVRALKPGEIYVS
HHHHEEEEECCCCHHHHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEE
HLTGFHVSKQEQLAGAKDPESAYDGKGYQGGIRFGSPIYDSKGKFSGMVLLTLDHQHLME
ECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHH
FTQHIDPGKGFGTLFPSYQSGNYAFLFDDEGWIITHPKYWDIRGVDQTGRLVPPYTADSK
HHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCEEECCCCCCCCCCCCCCCCCCC
QDDVDSGRIPFNLDHAGFIHKSYPTVSAAVRNRQEGFVDITNVGGAKKIMAYAPIFYDTG
CCCCCCCCCCEECCCCCCEECCCCHHHHHHHCCCCCCEEEECCCCHHHHHEECCEEECCC
DYARHGVFGGVTIGFQVDQFHEASHKGSRLIDRQLGEHRRTSALIILATALVSALSAWLL
CHHHCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRGISIPLRQLTESAGKLAAGDSHVRVAVNSSDEIGVLANTFNYMADELDLRKQSILSTL
HCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DELRKSRLEILDERNFKESVLESISSGIVTFSPQGRLTSINRTGRLFLGEGLAAETHYTE
HHHHHHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCEEECCCCCCEEECCCCCCCHHHHH
VFKGWGVLNERISQVLSKQSGYGRETFRFDHGPGKTHFDVGFFPIGADAEQGLTVTLRNE
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCEEEECCC
TQRENLQEEMMRLDRLASLGKLSAGIAHEVRNPLTGISLLLDDLHDQASSGPEDRDLIKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ALAEIERVEKLINALLNYSSPVRADFRECDLNRLVCDTVLLMRRQCERQKVQLNLTEGEV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
PPLRLDPEKIKQAVLNIIKNAQEALPEGGRIEVVTSVQDGYAVIGIGDDGPGIASHDLPL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCE
IFEPFFTRKGAGTGLGLSITQRIVEEHHGKVRVETAPGGGTRFTIELPL
EECHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEEEECC
>Mature Secondary Structure 
PRFTLFKKILVITLLLSLLPLFVSSAILLMNLQSISTKLTDEISRSDDRQATQSLQMKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RDLAENIRDFLHQCESDLLFLSRSRLDRSTLLDFYQTRLSEVWQRGASATATQGTHEFRP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IYRSIAIIDRNGMEQSAIRNGQLVPKEQLRNVADPANTEFKSEEYFRRVRALKPGEIYVS
HHHHEEEEECCCCHHHHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEE
HLTGFHVSKQEQLAGAKDPESAYDGKGYQGGIRFGSPIYDSKGKFSGMVLLTLDHQHLME
ECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHH
FTQHIDPGKGFGTLFPSYQSGNYAFLFDDEGWIITHPKYWDIRGVDQTGRLVPPYTADSK
HHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCEEECCCCCCCCCCCCCCCCCCC
QDDVDSGRIPFNLDHAGFIHKSYPTVSAAVRNRQEGFVDITNVGGAKKIMAYAPIFYDTG
CCCCCCCCCCEECCCCCCEECCCCHHHHHHHCCCCCCEEEECCCCHHHHHEECCEEECCC
DYARHGVFGGVTIGFQVDQFHEASHKGSRLIDRQLGEHRRTSALIILATALVSALSAWLL
CHHHCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRGISIPLRQLTESAGKLAAGDSHVRVAVNSSDEIGVLANTFNYMADELDLRKQSILSTL
HCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DELRKSRLEILDERNFKESVLESISSGIVTFSPQGRLTSINRTGRLFLGEGLAAETHYTE
HHHHHHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCEEECCCCCCEEECCCCCCCHHHHH
VFKGWGVLNERISQVLSKQSGYGRETFRFDHGPGKTHFDVGFFPIGADAEQGLTVTLRNE
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCEEEECCC
TQRENLQEEMMRLDRLASLGKLSAGIAHEVRNPLTGISLLLDDLHDQASSGPEDRDLIKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ALAEIERVEKLINALLNYSSPVRADFRECDLNRLVCDTVLLMRRQCERQKVQLNLTEGEV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
PPLRLDPEKIKQAVLNIIKNAQEALPEGGRIEVVTSVQDGYAVIGIGDDGPGIASHDLPL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCE
IFEPFFTRKGAGTGLGLSITQRIVEEHHGKVRVETAPGGGTRFTIELPL
EECHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]