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The map label for this gene is hinT [C]

Identifier: 197119030

GI number: 197119030

Start: 3071340

End: 3071684

Strand: Reverse

Name: hinT [C]

Synonym: Gbem_2653

Alternate gene names: 197119030

Gene position: 3071684-3071340 (Counterclockwise)

Preceding gene: 197119031

Following gene: 197119029

Centisome position: 66.56

GC content: 62.9

Gene sequence:

>345_bases
ATGAACGACTGCCTGTTCTGCAAGATGGCCAGCGGCGCGATCCCCGTCAAGAAGGTCTACGAGGACGACGAACTCTTCGC
CATCGAGGACATCAACCCCGTGGCGCCCTTGCACATGCTTATCATCCCCAAGAAGCACCTCGCGAACGCGCTGGCGCTTG
CTCCTGAGGACGACCGGATCATCGGTGCGATCCACCGGGTGGCTGCCAAGCTCGCCCGGGAGCGCGGCATGGACGAGGAA
GGGTTCCGCCTGGTGAACAATACCAACGCCGGCGCCGGCCAGTCCGTTTTCCATATCCATTTCCACCTGCTTGCCGGACG
CAACCTCGGGTGGCCTCCAGGGTAG

Upstream 100 bases:

>100_bases
AAACGCGGAAATGTTTGAAACCAACCCGGAGCTCTCTTCCTCTCTCAGATTCTCTCTCTGGCTAAAGGTTTTGGAGTTTG
ACTTTTAAAGGAGGTGTTAC

Downstream 100 bases:

>100_bases
TCCCTAACCGTAATCCATACAGGATCTGCACAAGGAGACTGACATGAAGAAGCTGCTTTTGCTTTTGCTCTTGCTATACC
CGCTGTCCGCTTTGGCTGAG

Product: purine nucleoside phosphoramidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MNDCLFCKMASGAIPVKKVYEDDELFAIEDINPVAPLHMLIIPKKHLANALALAPEDDRIIGAIHRVAAKLARERGMDEE
GFRLVNNTNAGAGQSVFHIHFHLLAGRNLGWPPG

Sequences:

>Translated_114_residues
MNDCLFCKMASGAIPVKKVYEDDELFAIEDINPVAPLHMLIIPKKHLANALALAPEDDRIIGAIHRVAAKLARERGMDEE
GFRLVNNTNAGAGQSVFHIHFHLLAGRNLGWPPG
>Mature_114_residues
MNDCLFCKMASGAIPVKKVYEDDELFAIEDINPVAPLHMLIIPKKHLANALALAPEDDRIIGAIHRVAAKLARERGMDEE
GFRLVNNTNAGAGQSVFHIHFHLLAGRNLGWPPG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=113, Percent_Identity=40.7079646017699, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI14211923, Length=111, Percent_Identity=36.9369369369369, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787346, Length=109, Percent_Identity=43.1192660550459, Blast_Score=87, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17506713, Length=113, Percent_Identity=43.3628318584071, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320078, Length=115, Percent_Identity=34.7826086956522, Blast_Score=64, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574010, Length=114, Percent_Identity=41.2280701754386, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24581222, Length=114, Percent_Identity=41.2280701754386, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12506; Mature: 12506

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDCLFCKMASGAIPVKKVYEDDELFAIEDINPVAPLHMLIIPKKHLANALALAPEDDRI
CCCEEEEEECCCCCCHHHHCCCCCEEEECCCCCCCCEEEEEECHHHHHHHEECCCCCCHH
IGAIHRVAAKLARERGMDEEGFRLVNNTNAGAGQSVFHIHFHLLAGRNLGWPPG
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MNDCLFCKMASGAIPVKKVYEDDELFAIEDINPVAPLHMLIIPKKHLANALALAPEDDRI
CCCEEEEEECCCCCCHHHHCCCCCEEEECCCCCCCCEEEEEECHHHHHHHEECCCCCCHH
IGAIHRVAAKLARERGMDEEGFRLVNNTNAGAGQSVFHIHFHLLAGRNLGWPPG
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]