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The map label for this gene is moaA [C]

Identifier: 197118992

GI number: 197118992

Start: 3032566

End: 3033981

Strand: Reverse

Name: moaA [C]

Synonym: Gbem_2615

Alternate gene names: 197118992

Gene position: 3033981-3032566 (Counterclockwise)

Preceding gene: 197118993

Following gene: 197118990

Centisome position: 65.74

GC content: 61.65

Gene sequence:

>1416_bases
ATGAAAACTACCGGTCCCGATGCAACCGAAAGCGTCTGCCCCGTTTGCCTCAAAAGAATCCCGGCCGAACGATTATTGGT
GGCCGACGAGGTGTTCCAGGTCAAACGGTGCGCAGAACACGGCGCCTTCAAGACCCTCATCTGGCGCGGAGAGCCTTCGC
TGGCAAAATGGCGCAGGCCTAAGGCACCTGTCCATCCCGAACTTTGCTATGGAACCCTCGACAAGGGGTGCCCTTTCGAT
TGCGGCCTCTGCAGCGACCATCGGCAGCTCCCTTGTTCCGTCCTGCTCGAAGTGACGGACCGCTGCAACCTGCAATGCGC
GTTCTGCTTTGCCGATGCCGGCCCTAAGGGTACAGAGGATCCTTCCCTTGAGCGGATCTCCTGGTTGTTGGAACGGGCCA
TGGCGGCGGCGGGGGCGTGCAGCCTGCAGCTGTCGGGGGGCGAGCCGACCCTGCGGGACGACCTTCCGGAGATCGTGGAA
GCAGCGCGGCGGATCGGCTTCTCCTTCATCCAGGTGAATACCAATGGCCTGCGCCTTGCCAGTGACAGAGCGTACGCGCA
GCGGCTGCAGGCTGCGGGGCTTTCGTCGGTCTTCCTCCAGTTCGACGGTGTTGACGACGAAATTTACCGTACCTTGAGGG
GAAGAGCGCTTTTGGAGCAGAAACTTTTGGCCGTCAGAAATGCCGGAGAGGCCGGCCTCGGGGTGGTCTTCGTCCCTACG
CTGGTCAGAGGGGTCAACACCGATGCTGTCGGAGCCATAGTGCGGCAAGCCCTGCAGCTTGCCCCGGTCGTGCGGGGCAT
CCATTTCCAGCCGGTCAGCTATTTCGGCCGCTTCCCCGAGGAAGAGTGTGGCGCGGACCGGTTCACCCTTCCCGAACTGA
TGAGGTGCCTTGAAGAACAGACCGGGAAACTGCTCAAGGTGGAGGATTTTTCTCCCCCCGGCGGGGAACATGCTCACTGC
TCCATGCACGCCACGTACCTCTACTCGGCAAACGGCGGACTCCGCCCGTTGGGGGCTGTGGGCGGCGACTCCTGCTGTAC
GACGGATTGCGGCAGCGGGGGGATCCGGCAAACCGTCGATACGGTGTCGCGTCGCTGGAAACTGCCGCCTGGAGTTCAAT
TTCCCAACGCCACTTCGACTTCTGGATCGTGCTGCTGCGGCGGGAGCGCGCCTGAGACCACCCGGGTCGAGGGCCCGGTC
GACTTGGACGTATTTCTCAAGGAGGTCTCCACCAGGAGCTTCACCATATCCGCCATGGCCTTTCAGGATGCCGAGAACCT
TGATCTGGAGCGGCTTAAGGGATGCTGCATTTCGGTGATATCCCCCGACGGAAAGCTGGTCCCCTTCTGCGCCTACAACC
TCACCAGCCGAGAGGGGAAAAGCCTCTACAGAAAGCAGCCAGGAGACGGATTATGA

Upstream 100 bases:

>100_bases
GCAAATGCGGCCAGATTGTGGCGGAAACCTATGACAAATGCATGGAAATACTGGCAAGCCACGGGTTCGAACCCGCAGCT
GGCAGGAAAGGATAAAGGTC

Downstream 100 bases:

>100_bases
AAATGACCCCGCTTGAGGGATGGCTTCGGGGAAAGGTGAGTGGTCACCGTGACGGAACCCTGGATGAGCAGATCGCCCGG
TACCAATTACGGAAACTGAG

Product: radical SAM protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKTTGPDATESVCPVCLKRIPAERLLVADEVFQVKRCAEHGAFKTLIWRGEPSLAKWRRPKAPVHPELCYGTLDKGCPFD
CGLCSDHRQLPCSVLLEVTDRCNLQCAFCFADAGPKGTEDPSLERISWLLERAMAAAGACSLQLSGGEPTLRDDLPEIVE
AARRIGFSFIQVNTNGLRLASDRAYAQRLQAAGLSSVFLQFDGVDDEIYRTLRGRALLEQKLLAVRNAGEAGLGVVFVPT
LVRGVNTDAVGAIVRQALQLAPVVRGIHFQPVSYFGRFPEEECGADRFTLPELMRCLEEQTGKLLKVEDFSPPGGEHAHC
SMHATYLYSANGGLRPLGAVGGDSCCTTDCGSGGIRQTVDTVSRRWKLPPGVQFPNATSTSGSCCCGGSAPETTRVEGPV
DLDVFLKEVSTRSFTISAMAFQDAENLDLERLKGCCISVISPDGKLVPFCAYNLTSREGKSLYRKQPGDGL

Sequences:

>Translated_471_residues
MKTTGPDATESVCPVCLKRIPAERLLVADEVFQVKRCAEHGAFKTLIWRGEPSLAKWRRPKAPVHPELCYGTLDKGCPFD
CGLCSDHRQLPCSVLLEVTDRCNLQCAFCFADAGPKGTEDPSLERISWLLERAMAAAGACSLQLSGGEPTLRDDLPEIVE
AARRIGFSFIQVNTNGLRLASDRAYAQRLQAAGLSSVFLQFDGVDDEIYRTLRGRALLEQKLLAVRNAGEAGLGVVFVPT
LVRGVNTDAVGAIVRQALQLAPVVRGIHFQPVSYFGRFPEEECGADRFTLPELMRCLEEQTGKLLKVEDFSPPGGEHAHC
SMHATYLYSANGGLRPLGAVGGDSCCTTDCGSGGIRQTVDTVSRRWKLPPGVQFPNATSTSGSCCCGGSAPETTRVEGPV
DLDVFLKEVSTRSFTISAMAFQDAENLDLERLKGCCISVISPDGKLVPFCAYNLTSREGKSLYRKQPGDGL
>Mature_471_residues
MKTTGPDATESVCPVCLKRIPAERLLVADEVFQVKRCAEHGAFKTLIWRGEPSLAKWRRPKAPVHPELCYGTLDKGCPFD
CGLCSDHRQLPCSVLLEVTDRCNLQCAFCFADAGPKGTEDPSLERISWLLERAMAAAGACSLQLSGGEPTLRDDLPEIVE
AARRIGFSFIQVNTNGLRLASDRAYAQRLQAAGLSSVFLQFDGVDDEIYRTLRGRALLEQKLLAVRNAGEAGLGVVFVPT
LVRGVNTDAVGAIVRQALQLAPVVRGIHFQPVSYFGRFPEEECGADRFTLPELMRCLEEQTGKLLKVEDFSPPGGEHAHC
SMHATYLYSANGGLRPLGAVGGDSCCTTDCGSGGIRQTVDTVSRRWKLPPGVQFPNATSTSGSCCCGGSAPETTRVEGPV
DLDVFLKEVSTRSFTISAMAFQDAENLDLERLKGCCISVISPDGKLVPFCAYNLTSREGKSLYRKQPGDGL

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG1964

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI22027536, Length=256, Percent_Identity=28.515625, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI116734668, Length=254, Percent_Identity=28.3464566929134, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1786999, Length=190, Percent_Identity=31.0526315789474, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 50972; Mature: 50972

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTGPDATESVCPVCLKRIPAERLLVADEVFQVKRCAEHGAFKTLIWRGEPSLAKWRRP
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCC
KAPVHPELCYGTLDKGCPFDCGLCSDHRQLPCSVLLEVTDRCNLQCAFCFADAGPKGTED
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCC
PSLERISWLLERAMAAAGACSLQLSGGEPTLRDDLPEIVEAARRIGFSFIQVNTNGLRLA
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEE
SDRAYAQRLQAAGLSSVFLQFDGVDDEIYRTLRGRALLEQKLLAVRNAGEAGLGVVFVPT
CHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHH
LVRGVNTDAVGAIVRQALQLAPVVRGIHFQPVSYFGRFPEEECGADRFTLPELMRCLEEQ
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHH
TGKLLKVEDFSPPGGEHAHCSMHATYLYSANGGLRPLGAVGGDSCCTTDCGSGGIRQTVD
CCCEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TVSRRWKLPPGVQFPNATSTSGSCCCGGSAPETTRVEGPVDLDVFLKEVSTRSFTISAMA
HHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEE
FQDAENLDLERLKGCCISVISPDGKLVPFCAYNLTSREGKSLYRKQPGDGL
ECCCCCCCHHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTTGPDATESVCPVCLKRIPAERLLVADEVFQVKRCAEHGAFKTLIWRGEPSLAKWRRP
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCC
KAPVHPELCYGTLDKGCPFDCGLCSDHRQLPCSVLLEVTDRCNLQCAFCFADAGPKGTED
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCC
PSLERISWLLERAMAAAGACSLQLSGGEPTLRDDLPEIVEAARRIGFSFIQVNTNGLRLA
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEE
SDRAYAQRLQAAGLSSVFLQFDGVDDEIYRTLRGRALLEQKLLAVRNAGEAGLGVVFVPT
CHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHH
LVRGVNTDAVGAIVRQALQLAPVVRGIHFQPVSYFGRFPEEECGADRFTLPELMRCLEEQ
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHH
TGKLLKVEDFSPPGGEHAHCSMHATYLYSANGGLRPLGAVGGDSCCTTDCGSGGIRQTVD
CCCEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TVSRRWKLPPGVQFPNATSTSGSCCCGGSAPETTRVEGPVDLDVFLKEVSTRSFTISAMA
HHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEE
FQDAENLDLERLKGCCISVISPDGKLVPFCAYNLTSREGKSLYRKQPGDGL
ECCCCCCCHHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]