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The map label for this gene is pleC [H]

Identifier: 197118913

GI number: 197118913

Start: 2936286

End: 2938775

Strand: Reverse

Name: pleC [H]

Synonym: Gbem_2536

Alternate gene names: 197118913

Gene position: 2938775-2936286 (Counterclockwise)

Preceding gene: 197118914

Following gene: 197118912

Centisome position: 63.68

GC content: 57.11

Gene sequence:

>2490_bases
ATGGATCTCACCTCAGGACAACATACGGATCCGGAAATACCCGGAAGGCGCGGGCGGACAGTGTATTCCTCCTTGCGGCA
GTCATTGACGGCACTGCTCTTCCTGCTGGTCCTGGCCGTGATAGGTTGCCTTGTCGCTAACCGGATATATGAGGGATATC
TGGCCGGCAAAGAACGCGGATCTGCCGCAATCCTCCTCGGCACCAAGGGATATGCGTTGTCGGCCGGCATCACCAGGAGG
GTCGCACTCCTGGAAGGGCTTTATGCCTTTACCGAGGCGAATACTTCTGAGTCGGATTTCGGGAGACGGTTCGACGTTTA
TGCCGCTGGGCTCCATGCGGGGGCCAAGGACGTTCGCCTTTTTGCCATAACCAGGGAAGGCGTCATCCGTTACCTTTACC
CGGTCAAAGGAAACGAGCGGGCGATGGAACTTGATCTGTTTCTCGCTCCACTAACGCGGGAAGATGCCTTAAGGACTTTG
AACAGCCGGGGCACCACTCTGAGCAACCCCTATGAATTGCGTCAAGGAGGCCTCGGAGTGGTGGCGCGCAAAGCGGTCTT
CGCCAAGGGGGAGTTCTGGGGGTTCGCGACCTTGGTCATCGATATCCCGTCAGTTCTCGCAGAGGCGGGACTGGATCGTC
AAGATCGCCTTGACATGACGGTGCGGGATCGAGCCGGGAAGGTTTTTTACGGTGACGCCGGGATATTCGCCAAGTCGCCG
GTCATGCTGCACATCGGGCTTCCTGAAGGCTACTGGGAACTTGCAGCCGTTCCAAAAGGCGGATGGGAGGCTCCCGTCCG
CAGAGATCTCCTGATCTTCAGGCTGGGGACCTTTTTTACTGCGTCCTGTCTCGCTTTCATTGTCTTCCAGATTTACGATC
GGCAACGGCGCCTCCGCAATGCGGTTCAAGAGCGGACGGCGGCGCTGAAGGAGATCGAAAATTATAACCGTACCTTGTTC
GAACTCTCTCCTATCGGCCTTGCCCTATGCAGCATGGACGGTGTGCTCGTGGACGTGAACACTGCTTATGCCGACATTTT
GGGGAGAACAGTCGCAGAGACGCTGGGACTTAGCTATTGGGAGATAACTCCTGAGAAATACGAGGACCAGGAAAGAATGC
GACTTGAACGGCTCGAAACGGTGGGCTTTTATGGTCCGTACGAGAAGGAGTACTGCCGCAGGGACGGCCGCTTGGTCCCG
GTCCGGCTCCATGGTCGCATCATTGAACGTAACAAAGCCCGTTTCATCTGGTCCAGCGTCGAGGATATCACCGATCGCAA
ACATGCCGAGGCCGAGATTAAACGCGAGCACGCCTTCTCGGAAGCTCTTATCGACAGCCTTCCCGGTGTCGTCTATCTAT
ACGACCAGGAGATGAACTTCCTCAGGTGGAACAAAAACTTCGAGCGGGTTACCGGTTATGCGCCGGAAGAGATCTTGCGT
CTGCAGCCGCTGGACTTTTTCGTAGAAAAGGATAAGGCGCTGCTCCAGAGCAGGATACAAGAGGTCTTCGTCAAAGGGGC
GTCGAATGTGGAGGCCGGGTTCGTGGCCAAAGACGGCAGCAGCGCCCCATACTTCTTCACCGGTTTGAGAACCGAGATCG
ATGGCAAGACCTGTTTGATAGGGATAGGGATCGACATCTCCGACCGCAAACGTTTAGAGGAAGAACTGACCGCCCTGAAC
CTCAATCTTGAGACCCGCGTAGCGGAGCGGACCCAGGAACTGAACGAGAAGAGCGCCCAGCTCGCAGCCGCCAACGAGAA
GCTCAAGGAAGTCGACCGCCTGAAGTCGATGTTCATCGCGTCCATGAGCCACGAGCTGCGCACCCCGCTGAATTCGGTGA
TAGGGTATTCGAGCATCATCCTCAATGAGTGGCTCGGACCTCTGCAGCCGACCCAGAAGGAGAATCTGGCCATCGTACTG
CGCGCCGGCAAGCACCTCCTTTCCCTGATAAACGACGTCATCGACGTTTCCAAGATCGAAGCGGGTCAAATCGAGGTACA
TAATGAGGAGTTCGACCTCTTCGATCTGGTGCAGGAGGCGGCCCAGCAGCTGGAGCCCGAAATCAGGGGTAAGGGGTTGG
CCTTTCCCGTCACCAATATCCACCTGCAACTGCTGGCCGACCGGCGCCGGCTGCTGCAGGCTGTGTTGAACCTGCTCAGT
AATGCCATGAAGTACACGGTAGAAGGATCGATTCAGCTCGCAGTAAATTTCGATGGGACCTGGGCCGAAATCTCCGTGGC
CGACTCCGGGATAGGCATCAGCGAGCAGGATGCCAAGCTGGTGTTTCAGCCCTTCCGACGGCTTGACTCTTCGCTCAGGG
GAACGGTTTCCGGAACCGGGCTTGGCCTCTACCTTACCAACAAGCTGGTGAGGGAGGTGCTGGGGGGGACGATAACTTTT
GTCAGCGCCGTCGGACAAGGTTCGACCTTTACCATCCGGATTCCGGTCACGGTCGGCGCCGATGCAGAGGCGAAGGAACG
CGTGTCCTGA

Upstream 100 bases:

>100_bases
AACGGATGAACGGGAGGTTCACCTTTCGTGACATAGTTGACGGTGCAGAGTTCAGGATCGAGATTGACAGCAAACCCGCT
GCCTGAAGGAGAAGACCAAG

Downstream 100 bases:

>100_bases
TCGTCTAAGGCTGGCAGCCTTTTATCGGGTGGACTGGAACATCAGGGAGTATGAAGTTATGAAGCAGGTACTGGTTATCG
AAGACAATCGGGACAACCTT

Product: sensor histidine kinase lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 829; Mature: 829

Protein sequence:

>829_residues
MDLTSGQHTDPEIPGRRGRTVYSSLRQSLTALLFLLVLAVIGCLVANRIYEGYLAGKERGSAAILLGTKGYALSAGITRR
VALLEGLYAFTEANTSESDFGRRFDVYAAGLHAGAKDVRLFAITREGVIRYLYPVKGNERAMELDLFLAPLTREDALRTL
NSRGTTLSNPYELRQGGLGVVARKAVFAKGEFWGFATLVIDIPSVLAEAGLDRQDRLDMTVRDRAGKVFYGDAGIFAKSP
VMLHIGLPEGYWELAAVPKGGWEAPVRRDLLIFRLGTFFTASCLAFIVFQIYDRQRRLRNAVQERTAALKEIENYNRTLF
ELSPIGLALCSMDGVLVDVNTAYADILGRTVAETLGLSYWEITPEKYEDQERMRLERLETVGFYGPYEKEYCRRDGRLVP
VRLHGRIIERNKARFIWSSVEDITDRKHAEAEIKREHAFSEALIDSLPGVVYLYDQEMNFLRWNKNFERVTGYAPEEILR
LQPLDFFVEKDKALLQSRIQEVFVKGASNVEAGFVAKDGSSAPYFFTGLRTEIDGKTCLIGIGIDISDRKRLEEELTALN
LNLETRVAERTQELNEKSAQLAAANEKLKEVDRLKSMFIASMSHELRTPLNSVIGYSSIILNEWLGPLQPTQKENLAIVL
RAGKHLLSLINDVIDVSKIEAGQIEVHNEEFDLFDLVQEAAQQLEPEIRGKGLAFPVTNIHLQLLADRRRLLQAVLNLLS
NAMKYTVEGSIQLAVNFDGTWAEISVADSGIGISEQDAKLVFQPFRRLDSSLRGTVSGTGLGLYLTNKLVREVLGGTITF
VSAVGQGSTFTIRIPVTVGADAEAKERVS

Sequences:

>Translated_829_residues
MDLTSGQHTDPEIPGRRGRTVYSSLRQSLTALLFLLVLAVIGCLVANRIYEGYLAGKERGSAAILLGTKGYALSAGITRR
VALLEGLYAFTEANTSESDFGRRFDVYAAGLHAGAKDVRLFAITREGVIRYLYPVKGNERAMELDLFLAPLTREDALRTL
NSRGTTLSNPYELRQGGLGVVARKAVFAKGEFWGFATLVIDIPSVLAEAGLDRQDRLDMTVRDRAGKVFYGDAGIFAKSP
VMLHIGLPEGYWELAAVPKGGWEAPVRRDLLIFRLGTFFTASCLAFIVFQIYDRQRRLRNAVQERTAALKEIENYNRTLF
ELSPIGLALCSMDGVLVDVNTAYADILGRTVAETLGLSYWEITPEKYEDQERMRLERLETVGFYGPYEKEYCRRDGRLVP
VRLHGRIIERNKARFIWSSVEDITDRKHAEAEIKREHAFSEALIDSLPGVVYLYDQEMNFLRWNKNFERVTGYAPEEILR
LQPLDFFVEKDKALLQSRIQEVFVKGASNVEAGFVAKDGSSAPYFFTGLRTEIDGKTCLIGIGIDISDRKRLEEELTALN
LNLETRVAERTQELNEKSAQLAAANEKLKEVDRLKSMFIASMSHELRTPLNSVIGYSSIILNEWLGPLQPTQKENLAIVL
RAGKHLLSLINDVIDVSKIEAGQIEVHNEEFDLFDLVQEAAQQLEPEIRGKGLAFPVTNIHLQLLADRRRLLQAVLNLLS
NAMKYTVEGSIQLAVNFDGTWAEISVADSGIGISEQDAKLVFQPFRRLDSSLRGTVSGTGLGLYLTNKLVREVLGGTITF
VSAVGQGSTFTIRIPVTVGADAEAKERVS
>Mature_829_residues
MDLTSGQHTDPEIPGRRGRTVYSSLRQSLTALLFLLVLAVIGCLVANRIYEGYLAGKERGSAAILLGTKGYALSAGITRR
VALLEGLYAFTEANTSESDFGRRFDVYAAGLHAGAKDVRLFAITREGVIRYLYPVKGNERAMELDLFLAPLTREDALRTL
NSRGTTLSNPYELRQGGLGVVARKAVFAKGEFWGFATLVIDIPSVLAEAGLDRQDRLDMTVRDRAGKVFYGDAGIFAKSP
VMLHIGLPEGYWELAAVPKGGWEAPVRRDLLIFRLGTFFTASCLAFIVFQIYDRQRRLRNAVQERTAALKEIENYNRTLF
ELSPIGLALCSMDGVLVDVNTAYADILGRTVAETLGLSYWEITPEKYEDQERMRLERLETVGFYGPYEKEYCRRDGRLVP
VRLHGRIIERNKARFIWSSVEDITDRKHAEAEIKREHAFSEALIDSLPGVVYLYDQEMNFLRWNKNFERVTGYAPEEILR
LQPLDFFVEKDKALLQSRIQEVFVKGASNVEAGFVAKDGSSAPYFFTGLRTEIDGKTCLIGIGIDISDRKRLEEELTALN
LNLETRVAERTQELNEKSAQLAAANEKLKEVDRLKSMFIASMSHELRTPLNSVIGYSSIILNEWLGPLQPTQKENLAIVL
RAGKHLLSLINDVIDVSKIEAGQIEVHNEEFDLFDLVQEAAQQLEPEIRGKGLAFPVTNIHLQLLADRRRLLQAVLNLLS
NAMKYTVEGSIQLAVNFDGTWAEISVADSGIGISEQDAKLVFQPFRRLDSSLRGTVSGTGLGLYLTNKLVREVLGGTITF
VSAVGQGSTFTIRIPVTVGADAEAKERVS

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=254, Percent_Identity=37.7952755905512, Blast_Score=160, Evalue=4e-40,
Organism=Escherichia coli, GI48994928, Length=406, Percent_Identity=27.3399014778325, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI87081816, Length=263, Percent_Identity=32.6996197718631, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI145693157, Length=293, Percent_Identity=32.4232081911263, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788713, Length=418, Percent_Identity=27.7511961722488, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=29.3103448275862, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786912, Length=285, Percent_Identity=27.719298245614, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786600, Length=260, Percent_Identity=28.4615384615385, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=28.6290322580645, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=27.0042194092827, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=25.6302521008403, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=28.7610619469027, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=232, Percent_Identity=28.0172413793103, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=26.5560165975104, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92455; Mature: 92455

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50839 CHASE ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTSGQHTDPEIPGRRGRTVYSSLRQSLTALLFLLVLAVIGCLVANRIYEGYLAGKERG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SAAILLGTKGYALSAGITRRVALLEGLYAFTEANTSESDFGRRFDVYAAGLHAGAKDVRL
CEEEEEECCCCEECCCHHHHHHHHHHHHHHHCCCCCCHHCCCEEEEEEHHHCCCCCCEEE
FAITREGVIRYLYPVKGNERAMELDLFLAPLTREDALRTLNSRGTTLSNPYELRQGGLGV
EEEECCCEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHCCCCCH
VARKAVFAKGEFWGFATLVIDIPSVLAEAGLDRQDRLDMTVRDRAGKVFYGDAGIFAKSP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEECCCCCEECCC
VMLHIGLPEGYWELAAVPKGGWEAPVRRDLLIFRLGTFFTASCLAFIVFQIYDRQRRLRN
EEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVQERTAALKEIENYNRTLFELSPIGLALCSMDGVLVDVNTAYADILGRTVAETLGLSYW
HHHHHHHHHHHHHHCCCEEEEECCHHEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCEE
EITPEKYEDQERMRLERLETVGFYGPYEKEYCRRDGRLVPVRLHGRIIERNKARFIWSSV
EECCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCEEEECCCCHHHHHHH
EDITDRKHAEAEIKREHAFSEALIDSLPGVVYLYDQEMNFLRWNKNFERVTGYAPEEILR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHHCCCHHHHCCCCHHHHHH
LQPLDFFVEKDKALLQSRIQEVFVKGASNVEAGFVAKDGSSAPYFFTGLRTEIDGKTCLI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEECCEEECCCCEEEE
GIGIDISDRKRLEEELTALNLNLETRVAERTQELNEKSAQLAAANEKLKEVDRLKSMFIA
EECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMSHELRTPLNSVIGYSSIILNEWLGPLQPTQKENLAIVLRAGKHLLSLINDVIDVSKIE
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCC
AGQIEVHNEEFDLFDLVQEAAQQLEPEIRGKGLAFPVTNIHLQLLADRRRLLQAVLNLLS
CCEEEEECCCCCHHHHHHHHHHHCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
NAMKYTVEGSIQLAVNFDGTWAEISVADSGIGISEQDAKLVFQPFRRLDSSLRGTVSGTG
HHHEEEEECEEEEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
LGLYLTNKLVREVLGGTITFVSAVGQGSTFTIRIPVTVGADAEAKERVS
EEHHHHHHHHHHHHCCCEEEHHHCCCCCEEEEEEEEEECCCCCHHHCCC
>Mature Secondary Structure
MDLTSGQHTDPEIPGRRGRTVYSSLRQSLTALLFLLVLAVIGCLVANRIYEGYLAGKERG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SAAILLGTKGYALSAGITRRVALLEGLYAFTEANTSESDFGRRFDVYAAGLHAGAKDVRL
CEEEEEECCCCEECCCHHHHHHHHHHHHHHHCCCCCCHHCCCEEEEEEHHHCCCCCCEEE
FAITREGVIRYLYPVKGNERAMELDLFLAPLTREDALRTLNSRGTTLSNPYELRQGGLGV
EEEECCCEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHCCCCCH
VARKAVFAKGEFWGFATLVIDIPSVLAEAGLDRQDRLDMTVRDRAGKVFYGDAGIFAKSP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEECCCCCEECCC
VMLHIGLPEGYWELAAVPKGGWEAPVRRDLLIFRLGTFFTASCLAFIVFQIYDRQRRLRN
EEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVQERTAALKEIENYNRTLFELSPIGLALCSMDGVLVDVNTAYADILGRTVAETLGLSYW
HHHHHHHHHHHHHHCCCEEEEECCHHEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCEE
EITPEKYEDQERMRLERLETVGFYGPYEKEYCRRDGRLVPVRLHGRIIERNKARFIWSSV
EECCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCEEEECCCCHHHHHHH
EDITDRKHAEAEIKREHAFSEALIDSLPGVVYLYDQEMNFLRWNKNFERVTGYAPEEILR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHHCCCHHHHCCCCHHHHHH
LQPLDFFVEKDKALLQSRIQEVFVKGASNVEAGFVAKDGSSAPYFFTGLRTEIDGKTCLI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEECCEEECCCCEEEE
GIGIDISDRKRLEEELTALNLNLETRVAERTQELNEKSAQLAAANEKLKEVDRLKSMFIA
EECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMSHELRTPLNSVIGYSSIILNEWLGPLQPTQKENLAIVLRAGKHLLSLINDVIDVSKIE
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCC
AGQIEVHNEEFDLFDLVQEAAQQLEPEIRGKGLAFPVTNIHLQLLADRRRLLQAVLNLLS
CCEEEEECCCCCHHHHHHHHHHHCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
NAMKYTVEGSIQLAVNFDGTWAEISVADSGIGISEQDAKLVFQPFRRLDSSLRGTVSGTG
HHHEEEEECEEEEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
LGLYLTNKLVREVLGGTITFVSAVGQGSTFTIRIPVTVGADAEAKERVS
EEHHHHHHHHHHHHCCCEEEHHHCCCCCEEEEEEEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]