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The map label for this gene is ccdB [C]

Identifier: 197118865

GI number: 197118865

Start: 2880925

End: 2881239

Strand: Direct

Name: ccdB [C]

Synonym: Gbem_2488

Alternate gene names: 197118865

Gene position: 2880925-2881239 (Clockwise)

Preceding gene: 197118864

Following gene: 197118866

Centisome position: 62.42

GC content: 56.51

Gene sequence:

>315_bases
ATGGCTCAATTCGAAGTTTACCGGAACGGGAATCCCAGGACCAGGGATGAGATCCCCTATCTGCTGGACGTGCAGGCGGA
GCTCTTGGCTTCCCTCGCCACACGGGTCGTCGTTCCTCTATTCACCGTCTCGGCAATGGGGAAGCCGGTCAGGCACCTAA
CGCCGAGGTTCAGCATCGAGAACAGAGATGTGGTCATGGTCACAGCGCAATTAGCCGGCATCGACCAGCAGGTCCTGGGA
GAAAAGGTGGGCTCCCTCGCGGAACGAAGAGAAGAAATAATCGCAGCACTCGATTTCCTTTTCACCGGATTCTAG

Upstream 100 bases:

>100_bases
CCAGCCGCAGCTGGCAGGAAGAAAACCGTGAAGCTATCGAAGAGTACAACAGCCGCGTGCAAAGCGATGGGACCTTCAGT
GACGATTTGAGGCATTTCTG

Downstream 100 bases:

>100_bases
GAAGAGACGTCATTATGACAATGCCTGCAGCCTCCCCCCTCGCCATAAACGAGCAGGTCGCGCGTGAACTGGAGCGGCTG
AAGAAGCGCCTTATCAACGC

Product: DNA gyrase-inactivating toxin CcdB

Products: protein histidine; sugar phosphate [C]

Alternate protein names: CcdB Protein; Cytotoxic Protein CcdB; Xin Of Gyrase Inhibiting Toxin-Antitoxin System; DNA Gyrase Inhibitor; DNA Gyrase-Inactivating xin CcdB; CcdB-Like Protein

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MAQFEVYRNGNPRTRDEIPYLLDVQAELLASLATRVVVPLFTVSAMGKPVRHLTPRFSIENRDVVMVTAQLAGIDQQVLG
EKVGSLAERREEIIAALDFLFTGF

Sequences:

>Translated_104_residues
MAQFEVYRNGNPRTRDEIPYLLDVQAELLASLATRVVVPLFTVSAMGKPVRHLTPRFSIENRDVVMVTAQLAGIDQQVLG
EKVGSLAERREEIIAALDFLFTGF
>Mature_103_residues
AQFEVYRNGNPRTRDEIPYLLDVQAELLASLATRVVVPLFTVSAMGKPVRHLTPRFSIENRDVVMVTAQLAGIDQQVLGE
KVGSLAERREEIIAALDFLFTGF

Specific function: Killing Of Plasmid-Free Segregants. Interferes With The Activity Of DNA Gyrase. Acts To Inhibit Partitioning Of The Chromosomal DNA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 11619; Mature: 11487

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFEVYRNGNPRTRDEIPYLLDVQAELLASLATRVVVPLFTVSAMGKPVRHLTPRFSIE
CCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
NRDVVMVTAQLAGIDQQVLGEKVGSLAERREEIIAALDFLFTGF
CCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQFEVYRNGNPRTRDEIPYLLDVQAELLASLATRVVVPLFTVSAMGKPVRHLTPRFSIE
CCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
NRDVVMVTAQLAGIDQQVLGEKVGSLAERREEIIAALDFLFTGF
CCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-phosphohistidine; sugar [C]

Specific reaction: Protein N-phosphohistidine + sugar = protein histidine + sugar phosphate [C]

General reaction: Acts to inhibit partitioning of the chromosomal DNA [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA